ATE396998T1 - Tetrazyklische imidazobenzodiazepine als gaba- rezeptormodulatoren - Google Patents
Tetrazyklische imidazobenzodiazepine als gaba- rezeptormodulatorenInfo
- Publication number
- ATE396998T1 ATE396998T1 AT05825935T AT05825935T ATE396998T1 AT E396998 T1 ATE396998 T1 AT E396998T1 AT 05825935 T AT05825935 T AT 05825935T AT 05825935 T AT05825935 T AT 05825935T AT E396998 T1 ATE396998 T1 AT E396998T1
- Authority
- AT
- Austria
- Prior art keywords
- imidazobenzodiazepines
- tetracyclic
- receptor modulators
- gaba receptor
- gaba
- Prior art date
Links
- 102000005915 GABA Receptors Human genes 0.000 title 1
- 108010005551 GABA Receptors Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
- A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04106556 | 2004-12-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE396998T1 true ATE396998T1 (de) | 2008-06-15 |
Family
ID=36129290
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05825935T ATE396998T1 (de) | 2004-12-14 | 2005-12-05 | Tetrazyklische imidazobenzodiazepine als gaba- rezeptormodulatoren |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US7432256B2 (de) |
| EP (1) | EP1828194B1 (de) |
| JP (1) | JP4783380B2 (de) |
| KR (1) | KR100923393B1 (de) |
| CN (1) | CN101115756B (de) |
| AR (1) | AR055005A1 (de) |
| AT (1) | ATE396998T1 (de) |
| AU (1) | AU2005315913B2 (de) |
| BR (1) | BRPI0515800A (de) |
| CA (1) | CA2590333C (de) |
| DE (1) | DE602005007265D1 (de) |
| ES (1) | ES2307230T3 (de) |
| MX (1) | MX2007007115A (de) |
| PL (1) | PL1828194T3 (de) |
| RU (1) | RU2393161C2 (de) |
| TW (1) | TW200631953A (de) |
| WO (1) | WO2006063708A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008064318A2 (en) * | 2006-11-22 | 2008-05-29 | University Of Medicine And Dentistry Of New Jersey | Peripheral opioid receptor active compounds |
| US10206921B2 (en) | 2009-06-03 | 2019-02-19 | The Regents Of The University Of California | Methods and compositions for treating a subject for central nervous system (CNS) injury |
| CN101891706B (zh) * | 2010-04-09 | 2013-05-29 | 复旦大学 | 3,4-二氢苯并[f][1,4]噻氮杂*类化合物或其盐及其药物用途 |
| US20130150351A1 (en) * | 2010-06-03 | 2013-06-13 | Stanley T. Carmichael | Methods and compositions for treating a subject for central nervous system (cns) injury |
| US20150374705A1 (en) | 2012-02-14 | 2015-12-31 | Shanghai Institues for Biological Sciences | Substances for treatment or relief of pain |
| CN112409363B (zh) * | 2013-12-20 | 2023-11-14 | 艾吉因生物股份有限公司 | 用于治疗认知损害的苯并二氮杂䓬衍生物、组合物和方法 |
| WO2016205739A1 (en) | 2015-06-19 | 2016-12-22 | Belew Mekonnen | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| US11505555B2 (en) | 2016-12-19 | 2022-11-22 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| US20180170941A1 (en) * | 2016-12-19 | 2018-06-21 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| BR112020026062B1 (pt) | 2018-06-19 | 2023-04-04 | Agenebio, Inc | Compostos derivados de benzodiazepina ou um sal farmaceuticamente aceitavel, isômero ou combinação dos mesmos, composição farmacêutica compreendendo os mesmos e usos dos mesmos para o tratamento de comprometimento cognitivo, câncer cerebral e psicose da doença de parkinson |
| WO2023174374A1 (zh) | 2022-03-16 | 2023-09-21 | 江苏恒瑞医药股份有限公司 | 稠杂环类化合物、其制备方法及其在医药上的应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1143728A (en) | 1979-10-04 | 1983-03-29 | Max Gerecke | Imidazodiazepine derivatives |
| EP0150040B1 (de) | 1984-01-19 | 1994-08-31 | F. Hoffmann-La Roche Ag | Imidazodiazepin-Derivate |
| DK174086D0 (da) | 1986-04-16 | 1986-04-16 | Ferrosan As | Nye benzodiazepinderivater samt fremgangsmaade til fremstilling af samme |
| US4897392A (en) | 1989-07-03 | 1990-01-30 | Hoechst-Roussel Pharmaceuticals, Inc. | 4H-indolo(1,2-d)(1,2,4)triazolo(4,3-A)(1,4)benzodiazepines |
| TW201311B (de) * | 1991-06-17 | 1993-03-01 | Hoffmann La Roche | |
| TWI239333B (en) * | 2000-11-16 | 2005-09-11 | Hoffmann La Roche | Benzodiazepine derivatives as GABA A receptor modulators |
| JP4783375B2 (ja) * | 2004-10-20 | 2011-09-28 | エフ．ホフマン−ラ ロシュ アーゲー | イミダゾベンゾジゼピン誘導体 |
-
2005
- 2005-12-05 ES ES05825935T patent/ES2307230T3/es not_active Expired - Lifetime
- 2005-12-05 DE DE602005007265T patent/DE602005007265D1/de not_active Expired - Lifetime
- 2005-12-05 BR BRPI0515800-1A patent/BRPI0515800A/pt not_active IP Right Cessation
- 2005-12-05 PL PL05825935T patent/PL1828194T3/pl unknown
- 2005-12-05 CA CA2590333A patent/CA2590333C/en not_active Expired - Fee Related
- 2005-12-05 KR KR1020077015973A patent/KR100923393B1/ko not_active Expired - Fee Related
- 2005-12-05 EP EP05825935A patent/EP1828194B1/de not_active Expired - Lifetime
- 2005-12-05 JP JP2007545890A patent/JP4783380B2/ja not_active Expired - Fee Related
- 2005-12-05 RU RU2007121767/04A patent/RU2393161C2/ru not_active IP Right Cessation
- 2005-12-05 MX MX2007007115A patent/MX2007007115A/es active IP Right Grant
- 2005-12-05 WO PCT/EP2005/012993 patent/WO2006063708A1/en not_active Ceased
- 2005-12-05 AT AT05825935T patent/ATE396998T1/de active
- 2005-12-05 AU AU2005315913A patent/AU2005315913B2/en not_active Ceased
- 2005-12-05 CN CN2005800479250A patent/CN101115756B/zh not_active Expired - Fee Related
- 2005-12-08 US US11/297,691 patent/US7432256B2/en not_active Expired - Fee Related
- 2005-12-12 TW TW094143881A patent/TW200631953A/zh unknown
- 2005-12-12 AR ARP050105181A patent/AR055005A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2008523125A (ja) | 2008-07-03 |
| US7432256B2 (en) | 2008-10-07 |
| RU2007121767A (ru) | 2009-01-27 |
| BRPI0515800A (pt) | 2008-08-05 |
| DE602005007265D1 (de) | 2008-07-10 |
| KR20070089227A (ko) | 2007-08-30 |
| RU2393161C2 (ru) | 2010-06-27 |
| CA2590333C (en) | 2013-01-08 |
| EP1828194B1 (de) | 2008-05-28 |
| WO2006063708A1 (en) | 2006-06-22 |
| CN101115756B (zh) | 2010-06-16 |
| AU2005315913A1 (en) | 2006-06-22 |
| CN101115756A (zh) | 2008-01-30 |
| ES2307230T3 (es) | 2008-11-16 |
| JP4783380B2 (ja) | 2011-09-28 |
| AR055005A1 (es) | 2007-08-01 |
| CA2590333A1 (en) | 2006-06-22 |
| EP1828194A1 (de) | 2007-09-05 |
| US20060128691A1 (en) | 2006-06-15 |
| KR100923393B1 (ko) | 2009-10-23 |
| PL1828194T3 (pl) | 2008-11-28 |
| TW200631953A (en) | 2006-09-16 |
| MX2007007115A (es) | 2007-07-11 |
| AU2005315913B2 (en) | 2011-11-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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