ATE393396T1 - Screening-tests für cannabinoid-ligand-artige modulatoren von gpr55 - Google Patents

Screening-tests für cannabinoid-ligand-artige modulatoren von gpr55

Info

Publication number
ATE393396T1
ATE393396T1 AT04710922T AT04710922T ATE393396T1 AT E393396 T1 ATE393396 T1 AT E393396T1 AT 04710922 T AT04710922 T AT 04710922T AT 04710922 T AT04710922 T AT 04710922T AT E393396 T1 ATE393396 T1 AT E393396T1
Authority
AT
Austria
Prior art keywords
gpr55
modulators
screening tests
cannabinoid ligand
cannabinoid
Prior art date
Application number
AT04710922T
Other languages
English (en)
Inventor
Tomas Drmota
Peter Greasley
Thierry Groblewski
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE393396T1 publication Critical patent/ATE393396T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/948Sedatives, e.g. cannabinoids, barbiturates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/02Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Anesthesiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Semiconductor Integrated Circuits (AREA)
  • Ceramic Capacitors (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
AT04710922T 2003-02-18 2004-02-13 Screening-tests für cannabinoid-ligand-artige modulatoren von gpr55 ATE393396T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US44866503P 2003-02-18 2003-02-18

Publications (1)

Publication Number Publication Date
ATE393396T1 true ATE393396T1 (de) 2008-05-15

Family

ID=32908627

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04710922T ATE393396T1 (de) 2003-02-18 2004-02-13 Screening-tests für cannabinoid-ligand-artige modulatoren von gpr55

Country Status (6)

Country Link
US (1) US20060194260A1 (de)
EP (1) EP1595146B1 (de)
AT (1) ATE393396T1 (de)
DE (1) DE602004013280T2 (de)
ES (1) ES2304604T3 (de)
WO (1) WO2004074844A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0808668D0 (en) * 2008-05-13 2008-06-18 Univ Aberdeen Materials and methods relating to a G-protein coupled receptor
AU2013266235B2 (en) 2012-05-25 2017-06-08 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods of regulating cannabinoid receptor activity-related disorders and diseases
EP2722669A1 (de) * 2012-10-22 2014-04-23 Securetec Detektions-Systeme AG Verfahren und Vorrichtung zum Nachweis von illegalen Drogen
US20160025753A1 (en) * 2014-07-25 2016-01-28 Microgenics Corporation Assay for cannabinoids and methods of use thereof
ES2593057B1 (es) * 2015-05-05 2017-09-12 Consejo Superior De Investigaciones Cientificas Moduladores selectivos de la actividad del receptor GPR55: derivados de cromenopirazol
PE20181199A1 (es) * 2015-09-30 2018-07-23 Bird Rock Bio Inc Anticuerpos que se unen al receptor cannabinoide 1 (cb1) humano
CN109420173B (zh) * 2017-08-31 2021-07-13 清华大学 Gpr55及其调节剂在防治免疫系统疾病中的应用
CN109946450B (zh) * 2019-04-16 2022-04-19 浙江诺迦生物科技有限公司 一种基于细胞内游离钙离子浓度变化效应的阿片类活性物质的检测方法及其检测试剂盒
CN110006866B (zh) * 2019-04-16 2022-04-22 杭州迈尔德生物科技有限公司 一种阿片类活性物质的通用检测方法及其检测试剂盒
CN109946451B (zh) * 2019-04-16 2022-05-20 浙江诺迦生物科技有限公司 一种基于细胞内游离钙离子浓度变化效应的大麻素类活性物质的检测方法及其检测试剂盒
CA3160038A1 (en) * 2019-12-02 2021-06-10 Dale Hunt Methods of screening compositions for cannabinoids

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1123397A2 (de) * 1998-10-16 2001-08-16 Millennium Pharmaceuticals, Inc. G-protein gekoppelter rezeptor
GB0010960D0 (en) * 2000-05-05 2000-06-28 Glaxo Group Ltd Assay
WO2002061087A2 (en) * 2000-12-19 2002-08-08 Lifespan Biosciences, Inc. Antigenic peptides, such as for g protein-coupled receptors (gpcrs), antibodies thereto, and systems for identifying such antigenic peptides

Also Published As

Publication number Publication date
EP1595146A1 (de) 2005-11-16
WO2004074844A1 (en) 2004-09-02
US20060194260A1 (en) 2006-08-31
ES2304604T3 (es) 2008-10-16
DE602004013280T2 (de) 2009-02-19
EP1595146B1 (de) 2008-04-23
DE602004013280D1 (de) 2008-06-05

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