ATE381532T1 - Verfahren zur herstellung von gabapentin - Google Patents
Verfahren zur herstellung von gabapentinInfo
- Publication number
- ATE381532T1 ATE381532T1 AT05015675T AT05015675T ATE381532T1 AT E381532 T1 ATE381532 T1 AT E381532T1 AT 05015675 T AT05015675 T AT 05015675T AT 05015675 T AT05015675 T AT 05015675T AT E381532 T1 ATE381532 T1 AT E381532T1
- Authority
- AT
- Austria
- Prior art keywords
- gabapentin
- desilylation
- producing gabapentin
- producing
- silylation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0416228.5A GB0416228D0 (en) | 2004-07-20 | 2004-07-20 | Process for the preparation of gabapentin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE381532T1 true ATE381532T1 (de) | 2008-01-15 |
Family
ID=32922525
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05015675T ATE381532T1 (de) | 2004-07-20 | 2005-07-19 | Verfahren zur herstellung von gabapentin |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7098362B2 (de) |
| EP (1) | EP1619181B1 (de) |
| AT (1) | ATE381532T1 (de) |
| DE (1) | DE602005003878D1 (de) |
| ES (1) | ES2296012T3 (de) |
| GB (1) | GB0416228D0 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010518014A (ja) | 2007-01-31 | 2010-05-27 | バーテックス ファーマシューティカルズ インコーポレイテッド | キナーゼ阻害剤として有用な２−アミノピリジン誘導体 |
| US8569337B2 (en) | 2008-07-23 | 2013-10-29 | Vertex Pharmaceuticals Incorporated | Tri-cyclic pyrazolopyridine kinase inhibitors |
| WO2010017350A1 (en) | 2008-08-06 | 2010-02-11 | Vertex Pharmaceuticals Incorporated | Aminopyridine kinase inhibitors |
| MX2012008643A (es) | 2010-01-27 | 2013-02-26 | Vertex Pharma | Inhibidores de cinasas de pirazolopiridinas. |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2460891C2 (de) | 1974-12-21 | 1982-09-23 | Gödecke AG, 1000 Berlin | 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
| US4894476A (en) | 1988-05-02 | 1990-01-16 | Warner-Lambert Company | Gabapentin monohydrate and a process for producing the same |
| DE3928182A1 (de) | 1989-08-25 | 1991-02-28 | Goedecke Ag | Verfahren zur herstellung von gabapentin |
| US5319135A (en) | 1989-08-25 | 1994-06-07 | Warner-Lambert Company | Process for cyclic amino acid anticonvulsant compounds |
| PH27359A (en) | 1989-08-25 | 1993-06-21 | Warner Lambert Co | Process for cyclic amino acid anticonvulsant compounds |
| FI905584A (fi) | 1989-11-16 | 1991-05-17 | Lonza Ag | Foerfarande foer framstaellning av 1-(aminometyl)cyklohexanaettikssyra. |
| IL119890A (en) | 1996-12-24 | 2002-03-10 | Teva Pharma | Gabapentin form iii and preparation of gabapentin form ii |
| US6294690B1 (en) | 1997-10-07 | 2001-09-25 | Warner-Lambert Company | Process for preparing a cyclic amino acid anticonvulsant compound |
| ITMI981535A1 (it) | 1998-07-03 | 2000-01-03 | Zambon Spa | Processo per la preparazione di gabapentina |
| ES2164527B1 (es) * | 1999-04-26 | 2003-04-01 | Medichen S A | Procedimiento de obtencion de gabapentina de calidad farmaceutica. |
| IT1319234B1 (it) | 2000-10-23 | 2003-09-26 | Zambon Spa | Processo di preparazione di gabapentina. |
| JP2004524339A (ja) | 2001-03-16 | 2004-08-12 | ソルケム イタリアーナ エス．ピー．エイ． | 環状アミノ酸の調製方法 |
| ITMI20011132A1 (it) | 2001-05-29 | 2002-11-29 | Procos Spa | Procedimento per la preparazione dell'acido 1-amminometil-1-cicloesanacetico |
| WO2003070683A1 (en) | 2002-02-22 | 2003-08-28 | Shasun Chemicals And Drugs Limited | Preparation of new mineral acid addition salts of gabapentin |
| WO2003089403A1 (en) | 2002-04-16 | 2003-10-30 | Taro Pharmaceutical Industries Ltd. | Process for preparing gabapentin |
-
2004
- 2004-07-20 GB GBGB0416228.5A patent/GB0416228D0/en not_active Ceased
-
2005
- 2005-07-19 EP EP05015675A patent/EP1619181B1/de not_active Not-in-force
- 2005-07-19 AT AT05015675T patent/ATE381532T1/de not_active IP Right Cessation
- 2005-07-19 DE DE602005003878T patent/DE602005003878D1/de active Active
- 2005-07-19 US US11/184,432 patent/US7098362B2/en not_active Expired - Fee Related
- 2005-07-19 ES ES05015675T patent/ES2296012T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US7098362B2 (en) | 2006-08-29 |
| DE602005003878D1 (de) | 2008-01-31 |
| ES2296012T3 (es) | 2008-04-16 |
| US20060020034A1 (en) | 2006-01-26 |
| GB0416228D0 (en) | 2004-08-25 |
| EP1619181B1 (de) | 2007-12-19 |
| EP1619181A1 (de) | 2006-01-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |