ATE374818T1 - Identifizierung und molekulare charakterisierung von protein, die in den speicheldrüsen von zecken exprimiert werden - Google Patents
Identifizierung und molekulare charakterisierung von protein, die in den speicheldrüsen von zecken exprimiert werdenInfo
- Publication number
- ATE374818T1 ATE374818T1 AT00934824T AT00934824T ATE374818T1 AT E374818 T1 ATE374818 T1 AT E374818T1 AT 00934824 T AT00934824 T AT 00934824T AT 00934824 T AT00934824 T AT 00934824T AT E374818 T1 ATE374818 T1 AT E374818T1
- Authority
- AT
- Austria
- Prior art keywords
- ticks
- salivary glands
- cdna library
- identification
- synthesised
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 4
- 241000238876 Acari Species 0.000 title abstract 3
- 238000012512 characterization method Methods 0.000 title abstract 2
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 210000004907 gland Anatomy 0.000 title 1
- 210000003079 salivary gland Anatomy 0.000 abstract 4
- 239000002299 complementary DNA Substances 0.000 abstract 3
- 108020004635 Complementary DNA Proteins 0.000 abstract 2
- 241001480843 Ixodes ricinus Species 0.000 abstract 2
- 108020004999 messenger RNA Proteins 0.000 abstract 2
- 239000005996 Blood meal Substances 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 238000010367 cloning Methods 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
- C07K14/43527—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from ticks
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Insects & Arthropods (AREA)
- Tropical Medicine & Parasitology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Virology (AREA)
- Anesthesiology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9913425.6A GB9913425D0 (en) | 1999-06-09 | 1999-06-09 | Identification and molecular characterisation of proteins expressed in the tick salivary glands |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE374818T1 true ATE374818T1 (de) | 2007-10-15 |
Family
ID=10855024
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00934824T ATE374818T1 (de) | 1999-06-09 | 2000-06-06 | Identifizierung und molekulare charakterisierung von protein, die in den speicheldrüsen von zecken exprimiert werden |
| AT07109568T ATE524548T1 (de) | 1999-06-09 | 2000-06-06 | Identifizierung und molekulare charakterisierung von in den speicheldrüsen von zecken exprimierten proteinen |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07109568T ATE524548T1 (de) | 1999-06-09 | 2000-06-06 | Identifizierung und molekulare charakterisierung von in den speicheldrüsen von zecken exprimierten proteinen |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6794166B2 (de) |
| EP (2) | EP1187916B1 (de) |
| JP (1) | JP2003502039A (de) |
| AT (2) | ATE374818T1 (de) |
| AU (1) | AU5055800A (de) |
| CA (1) | CA2376421A1 (de) |
| DE (1) | DE60036619T2 (de) |
| ES (1) | ES2293900T3 (de) |
| GB (1) | GB9913425D0 (de) |
| WO (1) | WO2000077198A2 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6835550B1 (en) * | 1998-04-15 | 2004-12-28 | Genencor International, Inc. | Mutant proteins having lower allergenic response in humans and methods for constructing, identifying and producing such proteins |
| US8277813B2 (en) | 1999-06-09 | 2012-10-02 | Edmond Godfroid | Identification and molecular characterisation of proteins, expressed in the Ixodes ricinus salivary glands |
| US20010046499A1 (en) * | 1999-12-03 | 2001-11-29 | Kantor Fred S. | Tick antigens and compositions and methods comprising them |
| EP1270723A1 (de) * | 2001-06-27 | 2003-01-02 | Henogen S.A. | Antikomplement-Polypeptide aus den Speicheldrüsen der Zecken Ixodes Ricinus |
| DE60230617D1 (de) * | 2001-06-27 | 2009-02-12 | Henogen S A | Antikomplement-polypeptide aus den speicheldrüsen der zecken ixodes ricinus |
| EP2045263A1 (de) * | 2007-10-02 | 2009-04-08 | Universite Libre De Bruxelles | Identifizierung und molekulare Charakterisierung von in den Speicheldrüsen von Zecken exprimierten Speichel-Metalloproteasen |
| EP2055715A1 (de) * | 2007-11-02 | 2009-05-06 | Universite Libre De Bruxelles | Antikomplement-Polypeptide von Ixodes ricinus |
| EP2123670B1 (de) * | 2008-05-22 | 2017-08-23 | Bioxodes SA | Koagulationshemmendes Polypeptid |
| US9670537B2 (en) | 2014-06-06 | 2017-06-06 | Titan Collaborative Kithe, Llc | Borrelia Provocation Procedure kit |
| DK3746469T3 (da) * | 2018-02-01 | 2024-08-19 | Bioxodes | Antikoagulerende proteiner og deres anvendelse til behandling af sygdomme associeret med aktiveringen af neutrofiler |
| EP3774877A1 (de) | 2018-03-28 | 2021-02-17 | Bioxodes | Antikoagulierende fusionsproteine und verwendungen davon |
| CA3092992A1 (en) * | 2018-04-17 | 2019-10-24 | Technische Universitat Braunschweig | Tick vaccine |
| WO2023023589A2 (en) * | 2021-08-18 | 2023-02-23 | The Trustees Of The University Of Pennsylvania | Mrna vaccines against tick salivary proteins, and methods of using same |
| WO2023222871A1 (en) | 2022-05-20 | 2023-11-23 | Bioxodes | Ixodes ricinus salivary gland polypeptide for preventing and treating brain inflammation |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995004750A1 (en) | 1993-08-09 | 1995-02-16 | Athena Neurosciences, Inc. | Tick derived protease inhibitor |
| JP2000083677A (ja) * | 1998-09-17 | 2000-03-28 | Bayer Ltd | ダニワクチン |
| EP2123670B1 (de) * | 2008-05-22 | 2017-08-23 | Bioxodes SA | Koagulationshemmendes Polypeptid |
-
1999
- 1999-06-09 GB GBGB9913425.6A patent/GB9913425D0/en not_active Ceased
-
2000
- 2000-06-06 WO PCT/BE2000/000061 patent/WO2000077198A2/en not_active Ceased
- 2000-06-06 ES ES00934824T patent/ES2293900T3/es not_active Expired - Lifetime
- 2000-06-06 DE DE60036619T patent/DE60036619T2/de not_active Expired - Lifetime
- 2000-06-06 AU AU50558/00A patent/AU5055800A/en not_active Abandoned
- 2000-06-06 JP JP2001503642A patent/JP2003502039A/ja active Pending
- 2000-06-06 AT AT00934824T patent/ATE374818T1/de not_active IP Right Cessation
- 2000-06-06 AT AT07109568T patent/ATE524548T1/de not_active IP Right Cessation
- 2000-06-06 EP EP00934824A patent/EP1187916B1/de not_active Expired - Lifetime
- 2000-06-06 EP EP07109568A patent/EP1892297B1/de not_active Expired - Lifetime
- 2000-06-06 CA CA002376421A patent/CA2376421A1/en not_active Abandoned
-
2001
- 2001-07-19 US US09/910,430 patent/US6794166B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE60036619D1 (de) | 2007-11-15 |
| EP1187916B1 (de) | 2007-10-03 |
| JP2003502039A (ja) | 2003-01-21 |
| ES2293900T3 (es) | 2008-04-01 |
| EP1892297B1 (de) | 2011-09-14 |
| GB9913425D0 (en) | 1999-08-11 |
| EP1892297A3 (de) | 2009-06-10 |
| DE60036619T2 (de) | 2008-08-07 |
| EP1892297A2 (de) | 2008-02-27 |
| AU5055800A (en) | 2001-01-02 |
| CA2376421A1 (en) | 2000-12-21 |
| WO2000077198A2 (en) | 2000-12-21 |
| US6794166B2 (en) | 2004-09-21 |
| EP1187916A2 (de) | 2002-03-20 |
| WO2000077198A3 (en) | 2001-03-15 |
| US20020127235A1 (en) | 2002-09-12 |
| ATE524548T1 (de) | 2011-09-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |