ATE374761T1 - Syntheseverfahren und benzoxathiepinzwischenprodukte - Google Patents

Syntheseverfahren und benzoxathiepinzwischenprodukte

Info

Publication number
ATE374761T1
ATE374761T1 AT05753693T AT05753693T ATE374761T1 AT E374761 T1 ATE374761 T1 AT E374761T1 AT 05753693 T AT05753693 T AT 05753693T AT 05753693 T AT05753693 T AT 05753693T AT E374761 T1 ATE374761 T1 AT E374761T1
Authority
AT
Austria
Prior art keywords
benzoxathie
synthesis process
intermediate products
products
synthesis
Prior art date
Application number
AT05753693T
Other languages
English (en)
Inventor
Bernard Vacher
Yves Brunel
Florence Castan-Cuisiat
Original Assignee
Pf Medicament
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pf Medicament filed Critical Pf Medicament
Application granted granted Critical
Publication of ATE374761T1 publication Critical patent/ATE374761T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT05753693T 2004-04-09 2005-04-08 Syntheseverfahren und benzoxathiepinzwischenprodukte ATE374761T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0403760A FR2868779B1 (fr) 2004-04-09 2004-04-09 Procede de synthese et intermediaires de benzoxathiepines

Publications (1)

Publication Number Publication Date
ATE374761T1 true ATE374761T1 (de) 2007-10-15

Family

ID=34946092

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05753693T ATE374761T1 (de) 2004-04-09 2005-04-08 Syntheseverfahren und benzoxathiepinzwischenprodukte

Country Status (20)

Country Link
US (1) US7902381B2 (de)
EP (1) EP1735297B1 (de)
JP (1) JP4922157B2 (de)
CN (1) CN1946708B (de)
AR (1) AR048865A1 (de)
AT (1) ATE374761T1 (de)
AU (1) AU2005235760B2 (de)
BR (1) BRPI0509383B1 (de)
CA (1) CA2562354C (de)
CY (1) CY1107109T1 (de)
DE (1) DE602005002738T2 (de)
DK (1) DK1735297T3 (de)
ES (1) ES2293587T3 (de)
FR (1) FR2868779B1 (de)
HK (1) HK1099931A1 (de)
MX (1) MXPA06011712A (de)
PL (1) PL1735297T3 (de)
PT (1) PT1735297E (de)
WO (1) WO2005103027A1 (de)
ZA (1) ZA200608385B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2908132B1 (fr) * 2006-11-08 2008-12-19 Pierre Fabre Medicament Sa Procede de synthese du n-[3-[(2-methoxyphenyl)sulfanyl]-2- methylpropyl]-3,4-dihydro-2h-1,5-benzoxathiepin-3-amine
JP5687704B2 (ja) * 2009-10-07 2015-03-18 カロ バイオ アクチェブラーグ 新規エストロゲン受容体リガンド

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3636074A (en) * 1968-08-05 1972-01-18 Hooker Chemical Corp Novel mercaptophenol derivatives
DE19501948A1 (de) * 1995-01-24 1996-07-25 Hoechst Ag Verfahren zur Herstellung von 2-Fluorphenylhydrazin
FR2787787B1 (fr) * 1998-12-23 2004-12-17 Rhodia Chimie Sa Procede de preparation de thioethers aromatiques de type diphenyle
FR2822467B1 (fr) * 2001-03-22 2003-12-12 Pf Medicament Derives benzoxathiepines et leur utilisation comme medicaments

Also Published As

Publication number Publication date
JP2007532520A (ja) 2007-11-15
JP4922157B2 (ja) 2012-04-25
BRPI0509383B1 (pt) 2018-07-10
US20080234499A1 (en) 2008-09-25
EP1735297A1 (de) 2006-12-27
EP1735297B1 (de) 2007-10-03
CA2562354C (fr) 2013-04-02
ZA200608385B (en) 2008-04-30
CA2562354A1 (fr) 2005-11-03
PL1735297T3 (pl) 2008-03-31
DK1735297T3 (da) 2008-02-11
BRPI0509383A (pt) 2007-09-18
AU2005235760A1 (en) 2005-11-03
CY1107109T1 (el) 2012-10-24
US7902381B2 (en) 2011-03-08
CN1946708B (zh) 2011-11-16
DE602005002738T2 (de) 2008-07-17
CN1946708A (zh) 2007-04-11
ES2293587T3 (es) 2008-03-16
MXPA06011712A (es) 2007-01-25
AU2005235760B2 (en) 2011-02-03
DE602005002738D1 (de) 2007-11-15
FR2868779B1 (fr) 2008-08-22
AR048865A1 (es) 2006-06-07
FR2868779A1 (fr) 2005-10-14
PT1735297E (pt) 2007-11-26
WO2005103027A1 (fr) 2005-11-03
HK1099931A1 (en) 2007-08-31

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