ATE374259T1 - Herstellung von matrizen aus polynukleotiden - Google Patents
Herstellung von matrizen aus polynukleotidenInfo
- Publication number
- ATE374259T1 ATE374259T1 AT02712025T AT02712025T ATE374259T1 AT E374259 T1 ATE374259 T1 AT E374259T1 AT 02712025 T AT02712025 T AT 02712025T AT 02712025 T AT02712025 T AT 02712025T AT E374259 T1 ATE374259 T1 AT E374259T1
- Authority
- AT
- Austria
- Prior art keywords
- polynucleotides
- matrices
- production
- array
- polynucelotides
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/00527—Sheets
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/00527—Sheets
- B01J2219/00529—DNA chips
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00585—Parallel processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00596—Solid-phase processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00608—DNA chips
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00612—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports the surface being inorganic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00623—Immobilisation or binding
- B01J2219/00626—Covalent
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00659—Two-dimensional arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00702—Processes involving means for analysing and characterising the products
- B01J2219/00707—Processes involving means for analysing and characterising the products separated from the reactor apparatus
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00722—Nucleotides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/30—Oligonucleotides characterised by their secondary structure
- C12Q2525/301—Hairpin oligonucleotides
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/771,708 US6787308B2 (en) | 1998-07-30 | 2001-01-30 | Arrayed biomolecules and their use in sequencing |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE374259T1 true ATE374259T1 (de) | 2007-10-15 |
Family
ID=25092716
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02712025T ATE374259T1 (de) | 2001-01-30 | 2002-01-30 | Herstellung von matrizen aus polynukleotiden |
Country Status (7)
Country | Link |
---|---|
EP (3) | EP1356120A2 (de) |
JP (1) | JP2004524525A (de) |
AT (1) | ATE374259T1 (de) |
AU (2) | AU2002231933A1 (de) |
DE (1) | DE60222628T2 (de) |
GB (1) | GB2389904A (de) |
WO (2) | WO2002061126A2 (de) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6780591B2 (en) | 1998-05-01 | 2004-08-24 | Arizona Board Of Regents | Method of determining the nucleotide sequence of oligonucleotides and DNA molecules |
US7875440B2 (en) | 1998-05-01 | 2011-01-25 | Arizona Board Of Regents | Method of determining the nucleotide sequence of oligonucleotides and DNA molecules |
US7056661B2 (en) | 1999-05-19 | 2006-06-06 | Cornell Research Foundation, Inc. | Method for sequencing nucleic acid molecules |
US6818395B1 (en) | 1999-06-28 | 2004-11-16 | California Institute Of Technology | Methods and apparatus for analyzing polynucleotide sequences |
US7211414B2 (en) | 2000-12-01 | 2007-05-01 | Visigen Biotechnologies, Inc. | Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity |
AU2002337030A1 (en) * | 2001-08-29 | 2003-03-18 | Genovoxx Gmbh | Method for analyzing nucleic acid sequences and gene expression |
EP1556506A1 (de) * | 2002-09-19 | 2005-07-27 | The Chancellor, Masters And Scholars Of The University Of Oxford | Molekulare arrays und einzelmolekülnachweis |
GB0304371D0 (en) | 2003-02-26 | 2003-04-02 | Solexa Ltd | DNA Sequence analysis |
AT501110A1 (de) * | 2003-09-16 | 2006-06-15 | Upper Austrian Res Gmbh | Arrays zur bindung von molekülen |
GB0324456D0 (en) | 2003-10-20 | 2003-11-19 | Isis Innovation | Parallel DNA sequencing methods |
GB0326073D0 (en) | 2003-11-07 | 2003-12-10 | Solexa Ltd | Improvements in or relating to polynucleotide arrays |
US7169560B2 (en) | 2003-11-12 | 2007-01-30 | Helicos Biosciences Corporation | Short cycle methods for sequencing polynucleotides |
US20050181383A1 (en) * | 2004-02-18 | 2005-08-18 | Xing Su | Isolating, positioning, and sequencing single molecules |
DE602005020421D1 (de) | 2004-02-19 | 2010-05-20 | Helicos Biosciences Corp | Verfahren zur analyse von polynukleotidsequenzen |
JP2005257275A (ja) * | 2004-03-09 | 2005-09-22 | National Institute Of Advanced Industrial & Technology | バイオチップおよびその製造方法、ならびに該チップを用いた化学物質の相互作用検出方法 |
US7170050B2 (en) | 2004-09-17 | 2007-01-30 | Pacific Biosciences Of California, Inc. | Apparatus and methods for optical analysis of molecules |
EP2463386B1 (de) | 2005-06-15 | 2017-04-12 | Complete Genomics Inc. | Nukleinsäureanalyse durch zufällige Mischungen von sich überlappenden Fragmenten |
GB0514935D0 (en) | 2005-07-20 | 2005-08-24 | Solexa Ltd | Methods for sequencing a polynucleotide template |
US7666593B2 (en) | 2005-08-26 | 2010-02-23 | Helicos Biosciences Corporation | Single molecule sequencing of captured nucleic acids |
EP2002017B1 (de) | 2006-04-04 | 2015-06-10 | Keygene N.V. | Nachweis von molekularmarkern mit hohem durchsatz auf der basis von restriktionsfragmenten |
PL2038425T3 (pl) | 2006-07-12 | 2011-03-31 | Keygene Nv | Wysokowydajne mapowanie fizyczne z zastosowaniem techniki AFLP |
BRPI0908734A2 (pt) | 2008-03-17 | 2015-07-28 | Expressive Res Bv | Métodos para a identificação de dna genômico em uma amostra e para a indentificação de polimorfismos, e, kit |
CN104862383B (zh) | 2008-03-28 | 2019-05-28 | 加利福尼亚太平洋生物科学股份有限公司 | 用于核酸测序的组合物和方法 |
JP2012514977A (ja) | 2009-01-13 | 2012-07-05 | キージーン・エン・フェー | 新規ゲノム配列決定戦略 |
US20120070829A1 (en) | 2010-09-10 | 2012-03-22 | Bio-Rad Laboratories, Inc. | Size selection of dna for chromatin analysis |
EP2980226A1 (de) | 2011-07-08 | 2016-02-03 | Keygene N.V. | Sequenzbasierte genotypisierung auf grundlage von oligonukleotid-verknüpfungsassays |
EP2964781B1 (de) | 2013-03-08 | 2018-01-10 | Roche Diagnostics GmbH | Bluttest auf egfr-mutationen |
GB201308259D0 (en) | 2013-05-08 | 2013-06-12 | Iles Raymond K | Cancer diagnosis and monitoring |
US10465232B1 (en) | 2015-10-08 | 2019-11-05 | Trace Genomics, Inc. | Methods for quantifying efficiency of nucleic acid extraction and detection |
WO2017087823A1 (en) | 2015-11-18 | 2017-05-26 | Mir Kalim U | Super-resolution sequencing |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5302509A (en) * | 1989-08-14 | 1994-04-12 | Beckman Instruments, Inc. | Method for sequencing polynucleotides |
WO1993005183A1 (en) * | 1991-09-09 | 1993-03-18 | Baylor College Of Medicine | Method and device for rapid dna or rna sequencing determination by a base addition sequencing scheme |
GB9208733D0 (en) * | 1992-04-22 | 1992-06-10 | Medical Res Council | Dna sequencing method |
US5314829A (en) * | 1992-12-18 | 1994-05-24 | California Institute Of Technology | Method for imaging informational biological molecules on a semiconductor substrate |
FR2716263B1 (fr) † | 1994-02-11 | 1997-01-17 | Pasteur Institut | Procédé d'alignement de macromolécules par passage d'un ménisque et applications dans un procédé de mise en évidence, séparation et/ou dosage d'une macromolécule dans un échantillon. |
US5604097A (en) * | 1994-10-13 | 1997-02-18 | Spectragen, Inc. | Methods for sorting polynucleotides using oligonucleotide tags |
SE9500589L (sv) * | 1995-02-17 | 1996-08-18 | Rudolf Rigler | Nukleinsyremolekyl detektion på fasta substrat vid enmolekyl DNA sekvensering |
WO1996027025A1 (en) * | 1995-02-27 | 1996-09-06 | Ely Michael Rabani | Device, compounds, algorithms, and methods of molecular characterization and manipulation with molecular parallelism |
ES2563643T3 (es) * | 1997-04-01 | 2016-03-15 | Illumina Cambridge Limited | Método de secuenciación de ácido nucleico |
US5919626A (en) * | 1997-06-06 | 1999-07-06 | Orchid Bio Computer, Inc. | Attachment of unmodified nucleic acids to silanized solid phase surfaces |
CN1152140C (zh) * | 1997-07-28 | 2004-06-02 | 医疗生物系统有限公司 | 核酸序列分析 |
US6169194B1 (en) † | 1997-10-16 | 2001-01-02 | Michael Thompson | High surface density covalent immobilization of oligonucleotide monolayers using a 1-(thiotrifluoroacetato)-11-(trichlorososilyl)-undecane linker |
GB0002310D0 (en) * | 2000-02-01 | 2000-03-22 | Solexa Ltd | Polynucleotide sequencing |
WO2000006770A1 (en) * | 1998-07-30 | 2000-02-10 | Solexa Ltd. | Arrayed biomolecules and their use in sequencing |
WO2000036152A1 (en) * | 1998-12-14 | 2000-06-22 | Li-Cor, Inc. | A system and methods for nucleic acid sequencing of single molecules by polymerase synthesis |
AU3567900A (en) * | 1999-03-30 | 2000-10-16 | Solexa Ltd. | Polynucleotide sequencing |
EP1077264B1 (de) * | 1999-06-07 | 2005-04-20 | Fuji Photo Film Co., Ltd. | DNA Chip, PNA Chip, sowie Herstellungsverfahren |
AU7537200A (en) * | 1999-09-29 | 2001-04-30 | Solexa Ltd. | Polynucleotide sequencing |
GB0002389D0 (en) * | 2000-02-02 | 2000-03-22 | Solexa Ltd | Molecular arrays |
GB0016473D0 (en) * | 2000-07-05 | 2000-08-23 | Amersham Pharm Biotech Uk Ltd | Sequencing method |
US7297518B2 (en) * | 2001-03-12 | 2007-11-20 | California Institute Of Technology | Methods and apparatus for analyzing polynucleotide sequences by asynchronous base extension |
-
2002
- 2002-01-30 AT AT02712025T patent/ATE374259T1/de not_active IP Right Cessation
- 2002-01-30 JP JP2002561061A patent/JP2004524525A/ja not_active Withdrawn
- 2002-01-30 AU AU2002231933A patent/AU2002231933A1/en not_active Abandoned
- 2002-01-30 WO PCT/GB2002/000438 patent/WO2002061126A2/en active IP Right Grant
- 2002-01-30 AU AU2002231934A patent/AU2002231934A1/en not_active Abandoned
- 2002-01-30 DE DE60222628T patent/DE60222628T2/de not_active Expired - Lifetime
- 2002-01-30 WO PCT/GB2002/000439 patent/WO2002061127A2/en not_active Application Discontinuation
- 2002-01-30 EP EP02712026A patent/EP1356120A2/de not_active Withdrawn
- 2002-01-30 GB GB0317837A patent/GB2389904A/en not_active Withdrawn
- 2002-01-30 EP EP02712025A patent/EP1356119B1/de not_active Expired - Lifetime
- 2002-01-30 EP EP07008271.4A patent/EP1808496B2/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU2002231933A1 (en) | 2002-08-12 |
WO2002061127A3 (en) | 2003-07-24 |
WO2002061126A3 (en) | 2003-02-06 |
WO2002061127A2 (en) | 2002-08-08 |
WO2002061126A2 (en) | 2002-08-08 |
EP1808496A1 (de) | 2007-07-18 |
DE60222628T2 (de) | 2008-07-17 |
EP1808496B2 (de) | 2021-12-22 |
EP1356119B1 (de) | 2007-09-26 |
DE60222628D1 (de) | 2007-11-08 |
JP2004524525A (ja) | 2004-08-12 |
EP1356119A2 (de) | 2003-10-29 |
GB2389904A (en) | 2003-12-24 |
GB0317837D0 (en) | 2003-09-03 |
EP1356120A2 (de) | 2003-10-29 |
EP1808496B1 (de) | 2012-08-08 |
AU2002231934A1 (en) | 2002-08-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |