ATE37365T1 - (3-aryl-2,3-dihydrobenzofuran-3-yl)alkylamine, ein verfahren zu ihrer herstellung und ihre verwendung als arzneimittel. - Google Patents
(3-aryl-2,3-dihydrobenzofuran-3-yl)alkylamine, ein verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.Info
- Publication number
- ATE37365T1 ATE37365T1 AT84114464T AT84114464T ATE37365T1 AT E37365 T1 ATE37365 T1 AT E37365T1 AT 84114464 T AT84114464 T AT 84114464T AT 84114464 T AT84114464 T AT 84114464T AT E37365 T1 ATE37365 T1 AT E37365T1
- Authority
- AT
- Austria
- Prior art keywords
- compounds
- dihydrobenzofuran
- alkylamines
- medicines
- aryl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/56—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups
- C07C215/58—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups with hydroxy groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
- C07C215/62—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups with hydroxy groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain the chain having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/225—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/559,134 US4602035A (en) | 1983-12-07 | 1983-12-07 | Antidepressant (3-aryl-2,3-dihydrobenzofuran-3-yl)alkylamines |
EP84114464A EP0149077B1 (de) | 1983-12-07 | 1984-11-29 | (3-Aryl-2,3-dihydrobenzofuran-3-yl)alkylamine, ein Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE37365T1 true ATE37365T1 (de) | 1988-10-15 |
Family
ID=24232407
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT84114464T ATE37365T1 (de) | 1983-12-07 | 1984-11-29 | (3-aryl-2,3-dihydrobenzofuran-3-yl)alkylamine, ein verfahren zu ihrer herstellung und ihre verwendung als arzneimittel. |
Country Status (7)
Country | Link |
---|---|
US (1) | US4602035A (de) |
EP (1) | EP0149077B1 (de) |
JP (1) | JPS60139684A (de) |
AT (1) | ATE37365T1 (de) |
DE (1) | DE3474143D1 (de) |
DK (1) | DK583084A (de) |
GR (1) | GR81183B (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2584723B1 (fr) * | 1985-07-09 | 1988-02-12 | Adir | Nouveaux derives du dihydro-2,3 benzofuranne, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
US4873241A (en) * | 1988-10-31 | 1989-10-10 | Fisons Corporation | 2-amino-N-(2-phenylindan-2-yl)acetamides useful as anti-epileptics |
FR2734816B1 (fr) * | 1995-05-31 | 1997-07-04 | Adir | Nouveaux aryl (alkyl) propylamides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
UA110324C2 (en) | 2009-07-02 | 2015-12-25 | Genentech Inc | Jak inhibitory compounds based on pyrazolo pyrimidine |
PT2688403T (pt) | 2011-03-23 | 2017-07-13 | Trevena Inc | Ligandos de recetores opioides e métodos de uso e fabrico dos mesmos |
US11061093B2 (en) | 2015-06-29 | 2021-07-13 | The Research Foundation For The State University Of New York | Dynamic phantom for functional magnetic resonance imaging |
AU2016372028B2 (en) | 2015-12-14 | 2022-02-17 | Trevena, Inc. | Methods of treating hyperalgesia |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3103520A (en) * | 1963-09-10 | Aminobenzoxacycloalkanes | ||
GB627839A (en) * | 1945-03-09 | 1949-08-17 | Abbott Lab | Improvements in the production of benzofuranone derivatives |
US2513698A (en) * | 1945-03-09 | 1950-07-04 | Abbott Lab | 2 (3) benxofuranone derivatives and methods of making them |
US3122551A (en) * | 1962-11-05 | 1964-02-25 | Abbott Lab | N-alkyl and n-aralkyl benzoxacycloalkaneamides |
US3156688A (en) * | 1962-11-05 | 1964-11-10 | Abbott Lab | Nu-alkyl and nu-aralkyl benzoxacycloalkanemethylamines |
GB1143703A (de) * | 1965-03-18 | |||
GB1526331A (en) * | 1976-01-14 | 1978-09-27 | Kefalas As | Phthalanes |
-
1983
- 1983-12-07 US US06/559,134 patent/US4602035A/en not_active Expired - Fee Related
-
1984
- 1984-11-29 DE DE8484114464T patent/DE3474143D1/de not_active Expired
- 1984-11-29 AT AT84114464T patent/ATE37365T1/de not_active IP Right Cessation
- 1984-11-29 EP EP84114464A patent/EP0149077B1/de not_active Expired
- 1984-12-05 GR GR81183A patent/GR81183B/el unknown
- 1984-12-06 JP JP59256602A patent/JPS60139684A/ja active Pending
- 1984-12-06 DK DK583084A patent/DK583084A/da not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
GR81183B (en) | 1985-04-08 |
DK583084A (da) | 1985-06-08 |
DK583084D0 (da) | 1984-12-06 |
EP0149077B1 (de) | 1988-09-21 |
EP0149077A1 (de) | 1985-07-24 |
DE3474143D1 (en) | 1988-10-27 |
US4602035A (en) | 1986-07-22 |
JPS60139684A (ja) | 1985-07-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |