ATE369419T1 - Deoxyribonuklease, dafür kodierendes gen und verfahren - Google Patents
Deoxyribonuklease, dafür kodierendes gen und verfahrenInfo
- Publication number
- ATE369419T1 ATE369419T1 AT00922949T AT00922949T ATE369419T1 AT E369419 T1 ATE369419 T1 AT E369419T1 AT 00922949 T AT00922949 T AT 00922949T AT 00922949 T AT00922949 T AT 00922949T AT E369419 T1 ATE369419 T1 AT E369419T1
- Authority
- AT
- Austria
- Prior art keywords
- expression vector
- dlad
- dna
- pharmaceutical composition
- host cell
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/22—Ribonucleases RNAses, DNAses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP23087099 | 1999-08-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE369419T1 true ATE369419T1 (de) | 2007-08-15 |
Family
ID=16914608
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00922949T ATE369419T1 (de) | 1999-08-17 | 2000-05-01 | Deoxyribonuklease, dafür kodierendes gen und verfahren |
Country Status (8)
Country | Link |
---|---|
US (3) | US6653118B1 (de) |
EP (1) | EP1122306B1 (de) |
JP (1) | JP4522632B2 (de) |
AT (1) | ATE369419T1 (de) |
AU (1) | AU4317200A (de) |
CA (1) | CA2346127A1 (de) |
DE (1) | DE60035851D1 (de) |
WO (1) | WO2001012793A1 (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1433842B1 (de) | 2002-12-18 | 2011-01-05 | Roche Diagnostics GmbH | Rekombinante Desoxyribonuclease I aus Rinder-Pankreas mit hoher spezifischer Aktivität |
DE60335602D1 (de) | 2002-12-18 | 2011-02-17 | Roche Diagnostics Gmbh | Rekombinante Desoxyribonuclease I aus Rinder-Pankreas mit hoher spezifischer Aktivität |
WO2006130034A1 (fr) * | 2005-04-25 | 2006-12-07 | Dmitry Dmitrievich Genkin | Procede pour prolonger la duree de vie d'animaux ou de l'humain |
US8710012B2 (en) * | 2003-07-14 | 2014-04-29 | Cls Therapeutics Limited | Method for treating oncological diseases |
US8388951B2 (en) | 2003-07-14 | 2013-03-05 | Cls Therapeutics Limited | Method for treating systemic DNA mutation disease |
US8431123B2 (en) * | 2003-07-14 | 2013-04-30 | Cls Therapeutics Limited | Method for treating systemic bacterial, fungal and protozoan infection |
PL2095825T3 (pl) * | 2006-11-28 | 2011-12-30 | Cls Therapeutics Ltd | Sposób leczenia ludzkich chorób związanych ze zwiększoną zawartością kwasu deoksyrybonukleinowego w przestrzeniach pozakomórkowych i tkankach i preparat leczniczy do przeprowadzenia tego sposobu |
US10617743B2 (en) | 2014-06-19 | 2020-04-14 | Cls Therapeutics Limited | Method to improve safety and efficacy of anti-cancer therapy |
JP6745873B2 (ja) | 2015-05-22 | 2020-08-26 | ドミトリエヴィッチ ゲンキン,ドミトリー | 神経変性における治療標的としての細胞外dna |
EP3351263A1 (de) * | 2017-01-20 | 2018-07-25 | Universitätsklinikum Hamburg-Eppendorf | Pharmazeutische zusammensetzung zur behandlung oder prävention von gewebeadhäsion |
KR20200122320A (ko) | 2018-01-16 | 2020-10-27 | 씨엘에스 테라퓨틱스 리미티드 | 데옥시리보뉴클레아제 (dnase) 활성을 갖는 효소의 간 발현에 의한 질환의 치료 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0449968B1 (de) * | 1988-12-23 | 1999-02-24 | Genentech, Inc. | Verfahren zur herstellung von menschlicher dnase |
JP3378706B2 (ja) * | 1994-09-06 | 2003-02-17 | 靖一 田沼 | 新規デオキシリボヌクレアーゼ |
EP0754751B1 (de) * | 1994-09-06 | 2001-09-19 | Seiichi Tanuma | Neuartige desoxyribonuklease |
DE69736276T2 (de) * | 1996-02-05 | 2007-08-30 | Genentech Inc., San Francisco | Menschliche dnase resistent gegen actininhibitoren |
US6265195B1 (en) * | 1996-04-25 | 2001-07-24 | Genentech, Inc. | Human DNase II |
US6358723B1 (en) * | 2000-04-03 | 2002-03-19 | Trustees Of Dartmouth College | Deoxyribonuclease IIβ proteins and cDNAs |
-
2000
- 2000-05-01 EP EP00922949A patent/EP1122306B1/de not_active Expired - Lifetime
- 2000-05-01 AU AU43172/00A patent/AU4317200A/en not_active Abandoned
- 2000-05-01 WO PCT/JP2000/002893 patent/WO2001012793A1/ja active IP Right Grant
- 2000-05-01 DE DE60035851T patent/DE60035851D1/de not_active Expired - Lifetime
- 2000-05-01 CA CA002346127A patent/CA2346127A1/en not_active Abandoned
- 2000-05-01 JP JP2001517678A patent/JP4522632B2/ja not_active Expired - Fee Related
- 2000-05-01 AT AT00922949T patent/ATE369419T1/de not_active IP Right Cessation
- 2000-05-01 US US09/807,784 patent/US6653118B1/en not_active Expired - Fee Related
-
2003
- 2003-09-25 US US10/670,863 patent/US7049123B2/en not_active Expired - Fee Related
-
2006
- 2006-01-19 US US11/335,754 patent/US7402310B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1122306A4 (de) | 2003-06-11 |
CA2346127A1 (en) | 2001-02-22 |
US7402310B2 (en) | 2008-07-22 |
EP1122306A1 (de) | 2001-08-08 |
JP4522632B2 (ja) | 2010-08-11 |
US6653118B1 (en) | 2003-11-25 |
EP1122306B1 (de) | 2007-08-08 |
US7049123B2 (en) | 2006-05-23 |
AU4317200A (en) | 2001-03-13 |
US20060110770A1 (en) | 2006-05-25 |
WO2001012793A1 (fr) | 2001-02-22 |
US20040157239A1 (en) | 2004-08-12 |
DE60035851D1 (de) | 2007-09-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |