ATE369419T1 - Deoxyribonuklease, dafür kodierendes gen und verfahren - Google Patents

Deoxyribonuklease, dafür kodierendes gen und verfahren

Info

Publication number
ATE369419T1
ATE369419T1 AT00922949T AT00922949T ATE369419T1 AT E369419 T1 ATE369419 T1 AT E369419T1 AT 00922949 T AT00922949 T AT 00922949T AT 00922949 T AT00922949 T AT 00922949T AT E369419 T1 ATE369419 T1 AT E369419T1
Authority
AT
Austria
Prior art keywords
expression vector
dlad
dna
pharmaceutical composition
host cell
Prior art date
Application number
AT00922949T
Other languages
English (en)
Inventor
Sei-Ichi Tanuma
Daisuke Shiokawa
Original Assignee
Sei-Ichi Tanuma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sei-Ichi Tanuma filed Critical Sei-Ichi Tanuma
Application granted granted Critical
Publication of ATE369419T1 publication Critical patent/ATE369419T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22Ribonucleases RNAses, DNAses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT00922949T 1999-08-17 2000-05-01 Deoxyribonuklease, dafür kodierendes gen und verfahren ATE369419T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP23087099 1999-08-17

Publications (1)

Publication Number Publication Date
ATE369419T1 true ATE369419T1 (de) 2007-08-15

Family

ID=16914608

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00922949T ATE369419T1 (de) 1999-08-17 2000-05-01 Deoxyribonuklease, dafür kodierendes gen und verfahren

Country Status (8)

Country Link
US (3) US6653118B1 (de)
EP (1) EP1122306B1 (de)
JP (1) JP4522632B2 (de)
AT (1) ATE369419T1 (de)
AU (1) AU4317200A (de)
CA (1) CA2346127A1 (de)
DE (1) DE60035851D1 (de)
WO (1) WO2001012793A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1433842B1 (de) 2002-12-18 2011-01-05 Roche Diagnostics GmbH Rekombinante Desoxyribonuclease I aus Rinder-Pankreas mit hoher spezifischer Aktivität
DE60335602D1 (de) 2002-12-18 2011-02-17 Roche Diagnostics Gmbh Rekombinante Desoxyribonuclease I aus Rinder-Pankreas mit hoher spezifischer Aktivität
WO2006130034A1 (fr) * 2005-04-25 2006-12-07 Dmitry Dmitrievich Genkin Procede pour prolonger la duree de vie d'animaux ou de l'humain
US8710012B2 (en) * 2003-07-14 2014-04-29 Cls Therapeutics Limited Method for treating oncological diseases
US8388951B2 (en) 2003-07-14 2013-03-05 Cls Therapeutics Limited Method for treating systemic DNA mutation disease
US8431123B2 (en) * 2003-07-14 2013-04-30 Cls Therapeutics Limited Method for treating systemic bacterial, fungal and protozoan infection
PL2095825T3 (pl) * 2006-11-28 2011-12-30 Cls Therapeutics Ltd Sposób leczenia ludzkich chorób związanych ze zwiększoną zawartością kwasu deoksyrybonukleinowego w przestrzeniach pozakomórkowych i tkankach i preparat leczniczy do przeprowadzenia tego sposobu
US10617743B2 (en) 2014-06-19 2020-04-14 Cls Therapeutics Limited Method to improve safety and efficacy of anti-cancer therapy
JP6745873B2 (ja) 2015-05-22 2020-08-26 ドミトリエヴィッチ ゲンキン,ドミトリー 神経変性における治療標的としての細胞外dna
EP3351263A1 (de) * 2017-01-20 2018-07-25 Universitätsklinikum Hamburg-Eppendorf Pharmazeutische zusammensetzung zur behandlung oder prävention von gewebeadhäsion
KR20200122320A (ko) 2018-01-16 2020-10-27 씨엘에스 테라퓨틱스 리미티드 데옥시리보뉴클레아제 (dnase) 활성을 갖는 효소의 간 발현에 의한 질환의 치료

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0449968B1 (de) * 1988-12-23 1999-02-24 Genentech, Inc. Verfahren zur herstellung von menschlicher dnase
JP3378706B2 (ja) * 1994-09-06 2003-02-17 靖一 田沼 新規デオキシリボヌクレアーゼ
EP0754751B1 (de) * 1994-09-06 2001-09-19 Seiichi Tanuma Neuartige desoxyribonuklease
DE69736276T2 (de) * 1996-02-05 2007-08-30 Genentech Inc., San Francisco Menschliche dnase resistent gegen actininhibitoren
US6265195B1 (en) * 1996-04-25 2001-07-24 Genentech, Inc. Human DNase II
US6358723B1 (en) * 2000-04-03 2002-03-19 Trustees Of Dartmouth College Deoxyribonuclease IIβ proteins and cDNAs

Also Published As

Publication number Publication date
EP1122306A4 (de) 2003-06-11
CA2346127A1 (en) 2001-02-22
US7402310B2 (en) 2008-07-22
EP1122306A1 (de) 2001-08-08
JP4522632B2 (ja) 2010-08-11
US6653118B1 (en) 2003-11-25
EP1122306B1 (de) 2007-08-08
US7049123B2 (en) 2006-05-23
AU4317200A (en) 2001-03-13
US20060110770A1 (en) 2006-05-25
WO2001012793A1 (fr) 2001-02-22
US20040157239A1 (en) 2004-08-12
DE60035851D1 (de) 2007-09-20

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties