ATE368024T1 - Stereoselektive synthese einer 4,4- disubstituierten cyclohexanpropansäure - Google Patents

Stereoselektive synthese einer 4,4- disubstituierten cyclohexanpropansäure

Info

Publication number
ATE368024T1
ATE368024T1 AT05708359T AT05708359T ATE368024T1 AT E368024 T1 ATE368024 T1 AT E368024T1 AT 05708359 T AT05708359 T AT 05708359T AT 05708359 T AT05708359 T AT 05708359T AT E368024 T1 ATE368024 T1 AT E368024T1
Authority
AT
Austria
Prior art keywords
cyclohexanepropane
disubstituted
acid
stereoselective synthesis
stereoselective
Prior art date
Application number
AT05708359T
Other languages
English (en)
Inventor
Karel Marie Joseph Brands
Sarah Elizabeth Brewer
Antony John Davies
Ulf H Dolling
Deborah Camille Hammond
David Ross Lieberman
Jeremy Peter Scott
Original Assignee
Merck Sharp & Dohme
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp & Dohme, Merck & Co Inc filed Critical Merck Sharp & Dohme
Application granted granted Critical
Publication of ATE368024T1 publication Critical patent/ATE368024T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/62—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings and other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/02—Preparation of sulfones; Preparation of sulfoxides by formation of sulfone or sulfoxide groups by oxidation of sulfides, or by formation of sulfone groups by oxidation of sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C07C319/16—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by addition of hydrogen sulfide or its salts to unsaturated compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/58—Preparation of carboxylic acid halides
    • C07C51/60—Preparation of carboxylic acid halides by conversion of carboxylic acids or their anhydrides or esters, lactones, salts into halides with the same carboxylic acid part
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/56—Unsaturated compounds containing hydroxy or O-metal groups containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09—Geometrical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT05708359T 2004-02-20 2005-02-16 Stereoselektive synthese einer 4,4- disubstituierten cyclohexanpropansäure ATE368024T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US54634304P 2004-02-20 2004-02-20

Publications (1)

Publication Number Publication Date
ATE368024T1 true ATE368024T1 (de) 2007-08-15

Family

ID=34886259

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05708359T ATE368024T1 (de) 2004-02-20 2005-02-16 Stereoselektive synthese einer 4,4- disubstituierten cyclohexanpropansäure

Country Status (17)

Country Link
US (1) US7411088B2 (de)
EP (1) EP1718593B1 (de)
JP (1) JP4719162B2 (de)
CN (1) CN100443458C (de)
AR (1) AR047666A1 (de)
AT (1) ATE368024T1 (de)
AU (1) AU2005214131B2 (de)
CA (1) CA2556348C (de)
CY (1) CY1108519T1 (de)
DE (1) DE602005001766T2 (de)
DK (1) DK1718593T3 (de)
ES (1) ES2290887T3 (de)
PL (1) PL1718593T3 (de)
PT (1) PT1718593E (de)
SI (1) SI1718593T1 (de)
TW (1) TWI352075B (de)
WO (1) WO2005080309A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0120347D0 (en) * 2001-08-21 2001-10-17 Merck Sharp & Dohme Therapeutic agents
CN111393253B (zh) * 2019-01-02 2022-11-29 江苏广域化学有限公司 一种含有反式取代环己基的化合物的合成方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3601197A (en) * 1970-04-29 1971-08-24 Exxon Production Research Co Treatment of formations with aryl sulfonic acid
US4612254A (en) * 1985-03-07 1986-09-16 Occidental Chemical Corporation Aromatic carboxylic acid and metal-modified phenolic resins and methods of preparation
US6214331B1 (en) * 1995-06-06 2001-04-10 C. R. Bard, Inc. Process for the preparation of aqueous dispersions of particles of water-soluble polymers and the particles obtained
GB0108591D0 (en) 2001-04-05 2001-05-23 Merck Sharp & Dohme Therapeutic agents
GB0108592D0 (en) * 2001-04-05 2001-05-23 Merck Sharp & Dohme Therapeutic agents
GB0120347D0 (en) * 2001-08-21 2001-10-17 Merck Sharp & Dohme Therapeutic agents
HRP20040075B1 (en) 2001-08-21 2012-03-31 Merck Sharp & Dohme Limited Novel cyclohexyl sulphones
GB0218041D0 (en) * 2002-08-02 2002-09-11 Merck Sharp & Dohme Chemical process
GB0223039D0 (en) * 2002-10-04 2002-11-13 Merck Sharp & Dohme Therapeutic compounds
GB0318447D0 (en) * 2003-08-05 2003-09-10 Merck Sharp & Dohme Therapeutic agents

Also Published As

Publication number Publication date
AU2005214131B2 (en) 2010-12-16
DK1718593T3 (da) 2007-10-22
DE602005001766T2 (de) 2008-04-30
CA2556348A1 (en) 2005-09-01
ES2290887T3 (es) 2008-02-16
EP1718593B1 (de) 2007-07-25
CA2556348C (en) 2013-01-08
JP4719162B2 (ja) 2011-07-06
WO2005080309A1 (en) 2005-09-01
SI1718593T1 (sl) 2007-12-31
PL1718593T3 (pl) 2007-12-31
DE602005001766D1 (de) 2007-09-06
CN100443458C (zh) 2008-12-17
TW200602309A (en) 2006-01-16
WO2005080309A8 (en) 2005-11-03
AR047666A1 (es) 2006-02-01
US7411088B2 (en) 2008-08-12
PT1718593E (pt) 2007-10-17
JP2007523141A (ja) 2007-08-16
EP1718593A1 (de) 2006-11-08
CN1918106A (zh) 2007-02-21
AU2005214131A1 (en) 2005-09-01
TWI352075B (en) 2011-11-11
CY1108519T1 (el) 2012-05-23
US20070225520A1 (en) 2007-09-27

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