ATE366740T1 - Auswahlverfahren zur erzeugung effizienter pack- zellen für lentivirale vektoren - Google Patents

Auswahlverfahren zur erzeugung effizienter pack- zellen für lentivirale vektoren

Info

Publication number
ATE366740T1
ATE366740T1 AT99962651T AT99962651T ATE366740T1 AT E366740 T1 ATE366740 T1 AT E366740T1 AT 99962651 T AT99962651 T AT 99962651T AT 99962651 T AT99962651 T AT 99962651T AT E366740 T1 ATE366740 T1 AT E366740T1
Authority
AT
Austria
Prior art keywords
selection process
lentiviral vectors
efficient packing
generating efficient
packing cells
Prior art date
Application number
AT99962651T
Other languages
English (en)
Inventor
Ryan Mcguinness
Luigi Naldini
Original Assignee
Cell Genesys Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cell Genesys Inc filed Critical Cell Genesys Inc
Application granted granted Critical
Publication of ATE366740T1 publication Critical patent/ATE366740T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16051—Methods of production or purification of viral material
    • C12N2740/16052—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Auxiliary Devices For And Details Of Packaging Control (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
AT99962651T 1998-11-13 1999-11-12 Auswahlverfahren zur erzeugung effizienter pack- zellen für lentivirale vektoren ATE366740T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10816998P 1998-11-13 1998-11-13

Publications (1)

Publication Number Publication Date
ATE366740T1 true ATE366740T1 (de) 2007-08-15

Family

ID=22320695

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99962651T ATE366740T1 (de) 1998-11-13 1999-11-12 Auswahlverfahren zur erzeugung effizienter pack- zellen für lentivirale vektoren

Country Status (7)

Country Link
EP (1) EP1129100B1 (de)
JP (1) JP4482639B2 (de)
AT (1) ATE366740T1 (de)
AU (1) AU1905300A (de)
CA (2) CA2803417A1 (de)
DE (1) DE69936531T2 (de)
WO (1) WO2000029421A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3526844B2 (ja) 1999-06-22 2004-05-17 株式会社ディナベック研究所 ２つの外来遺伝子を発現させるためのベクター
ATE381620T1 (de) 2003-04-24 2008-01-15 San Raffaele Centro Fond Synthetische bidirektionale promotoren und deren verwendungen

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5716826A (en) * 1988-03-21 1998-02-10 Chiron Viagene, Inc. Recombinant retroviruses
ES2187504T3 (es) * 1992-02-28 2003-06-16 Syngenix Ltd Vectores no oncovirales, basados en el vmmp, con encapsidacion defectuosa.
US5739118A (en) * 1994-04-01 1998-04-14 Apollon, Inc. Compositions and methods for delivery of genetic material
US5693508A (en) * 1994-11-08 1997-12-02 Chang; Lung-Ji Retroviral expression vectors containing MoMLV/CMV-IE/HIV-TAR chimeric long terminal repeats
WO1998039463A2 (en) * 1997-03-06 1998-09-11 Ueberla Klaus Lentivirus based vector and vector system

Also Published As

Publication number Publication date
CA2803417A1 (en) 2000-05-25
EP1129100A1 (de) 2001-09-05
WO2000029421A1 (en) 2000-05-25
EP1129100A4 (de) 2003-01-15
EP1129100B1 (de) 2007-07-11
DE69936531T2 (de) 2008-04-03
CA2349617C (en) 2015-04-28
JP4482639B2 (ja) 2010-06-16
JP2002530057A (ja) 2002-09-17
CA2349617A1 (en) 2000-05-25
AU1905300A (en) 2000-06-05
DE69936531D1 (de) 2007-08-23

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties