ATE361761T1 - Poly(ethylen glykol)-konjugate von insulinähnlichem wachstumfaktor bindenden protein-4 - Google Patents
Poly(ethylen glykol)-konjugate von insulinähnlichem wachstumfaktor bindenden protein-4Info
- Publication number
- ATE361761T1 ATE361761T1 AT03778269T AT03778269T ATE361761T1 AT E361761 T1 ATE361761 T1 AT E361761T1 AT 03778269 T AT03778269 T AT 03778269T AT 03778269 T AT03778269 T AT 03778269T AT E361761 T1 ATE361761 T1 AT E361761T1
- Authority
- AT
- Austria
- Prior art keywords
- insulin
- growth factor
- binding protein
- factor binding
- conjugates
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02021844 | 2002-09-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE361761T1 true ATE361761T1 (de) | 2007-06-15 |
Family
ID=32039114
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03778269T ATE361761T1 (de) | 2002-09-27 | 2003-09-25 | Poly(ethylen glykol)-konjugate von insulinähnlichem wachstumfaktor bindenden protein-4 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20060100144A1 (de) |
| EP (1) | EP1545623B1 (de) |
| JP (1) | JP4237703B2 (de) |
| AT (1) | ATE361761T1 (de) |
| AU (1) | AU2003285286A1 (de) |
| CA (1) | CA2498062C (de) |
| DE (1) | DE60313786T2 (de) |
| ES (1) | ES2285215T3 (de) |
| WO (1) | WO2004028568A1 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006034832A2 (en) * | 2004-09-27 | 2006-04-06 | Univ Muenchen L Maximilians | Use of igfbp-2 in senescence diseases and for the maintenance of organ functions |
| WO2006094530A1 (en) * | 2005-03-11 | 2006-09-14 | Siegfried Ltd. | Di-polymer protein conjugates and processes for their preparation |
| JP2011507801A (ja) | 2007-09-11 | 2011-03-10 | ユニバーシティ オブ マサチューセッツ | 癌の処置のためのインスリン様成長因子結合タンパク質７ |
| CN102481367B (zh) | 2009-07-06 | 2015-04-29 | 弗·哈夫曼-拉罗切有限公司 | 结合地高辛配基的双特异性抗体 |
| US20130041134A1 (en) * | 2009-11-05 | 2013-02-14 | Sangart ,Inc. | Methods for preparing polyethylene glycol maleimide using n-(2-hydroxyethyl) maleimide as a starting material |
| JP2014502607A (ja) | 2011-01-03 | 2014-02-03 | エフ．ホフマン−ラ ロシュ アーゲー | 抗ｄｉｇ抗体およびペプチドと結合体化しているジゴキシゲニンの複合体の薬学的組成物 |
| US9290744B2 (en) | 2011-09-14 | 2016-03-22 | University Of Massachusetts | SRPX for treatment of cancer |
| LT3183264T (lt) * | 2014-08-19 | 2021-01-11 | Biogen Ma Inc. | Pegilinimo būdas |
| US10046058B2 (en) | 2014-12-02 | 2018-08-14 | Rezolute, Inc. | Use of hydrophobic organic acids to increase hydrophobicity of proteins and protein conjugates |
| MX2017014586A (es) | 2015-06-04 | 2018-03-09 | Antriabio Inc | Pegilacion de aminas para la preparacion de conjugados de proteinas especificos de un sitio. |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6004775A (en) * | 1990-08-03 | 1999-12-21 | The Salk Institute For Biological Studies | DNA encoding IGFBP-4 |
| US5212074A (en) * | 1990-08-28 | 1993-05-18 | Chiron Corporation | Genetic material encoding new insulin-like growth factor binding protein igfbp-6 |
| US5382657A (en) * | 1992-08-26 | 1995-01-17 | Hoffmann-La Roche Inc. | Peg-interferon conjugates |
| US6207640B1 (en) * | 1994-04-07 | 2001-03-27 | Genentech, Inc. | Treatment of partial growth hormone insensitivity syndrome |
| US5932462A (en) * | 1995-01-10 | 1999-08-03 | Shearwater Polymers, Inc. | Multiarmed, monofunctional, polymer for coupling to molecules and surfaces |
| US5672662A (en) * | 1995-07-07 | 1997-09-30 | Shearwater Polymers, Inc. | Poly(ethylene glycol) and related polymers monosubstituted with propionic or butanoic acids and functional derivatives thereof for biotechnical applications |
| US6841386B2 (en) * | 2001-04-10 | 2005-01-11 | Viacell, Inc. | Modulation of primary stem cell differentiation using an insulin-like growth factor binding protein |
| EP1399475A2 (de) * | 2001-06-07 | 2004-03-24 | F. Hoffmann-La Roche Ag | Mutanten igf-bindender proteine und verfahren zur produktion deren antagonisten |
-
2003
- 2003-09-25 AT AT03778269T patent/ATE361761T1/de not_active IP Right Cessation
- 2003-09-25 ES ES03778269T patent/ES2285215T3/es not_active Expired - Lifetime
- 2003-09-25 AU AU2003285286A patent/AU2003285286A1/en not_active Abandoned
- 2003-09-25 CA CA2498062A patent/CA2498062C/en not_active Expired - Fee Related
- 2003-09-25 WO PCT/EP2003/010658 patent/WO2004028568A1/en active IP Right Grant
- 2003-09-25 EP EP03778269A patent/EP1545623B1/de not_active Expired - Lifetime
- 2003-09-25 JP JP2004539015A patent/JP4237703B2/ja not_active Expired - Fee Related
- 2003-09-25 DE DE60313786T patent/DE60313786T2/de not_active Expired - Lifetime
- 2003-09-26 US US10/529,090 patent/US20060100144A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2006503843A (ja) | 2006-02-02 |
| EP1545623B1 (de) | 2007-05-09 |
| US20060100144A1 (en) | 2006-05-11 |
| WO2004028568A1 (en) | 2004-04-08 |
| ES2285215T3 (es) | 2007-11-16 |
| CA2498062C (en) | 2010-05-25 |
| JP4237703B2 (ja) | 2009-03-11 |
| DE60313786D1 (de) | 2007-06-21 |
| CA2498062A1 (en) | 2004-04-08 |
| DE60313786T2 (de) | 2008-01-24 |
| EP1545623A1 (de) | 2005-06-29 |
| AU2003285286A1 (en) | 2004-04-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |