ATE356157T1 - Perfluoroalkylpolyetherpolymere für ophthalmische anwendungen - Google Patents

Perfluoroalkylpolyetherpolymere für ophthalmische anwendungen

Info

Publication number
ATE356157T1
ATE356157T1 AT99948749T AT99948749T ATE356157T1 AT E356157 T1 ATE356157 T1 AT E356157T1 AT 99948749 T AT99948749 T AT 99948749T AT 99948749 T AT99948749 T AT 99948749T AT E356157 T1 ATE356157 T1 AT E356157T1
Authority
AT
Austria
Prior art keywords
polymers
ophthalmic applications
polyether polymers
perfluoroalkyl polyether
porous
Prior art date
Application number
AT99948749T
Other languages
German (de)
English (en)
Inventor
Hassan Chaouk
Timothy Charles Hughes
John Stuart Wilkie
Gordon Francis Meijs
Original Assignee
Commw Scient Ind Res Org
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commw Scient Ind Res Org filed Critical Commw Scient Ind Res Org
Application granted granted Critical
Publication of ATE356157T1 publication Critical patent/ATE356157T1/de

Links

Classifications

    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/04Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
    • G02B1/041Lenses
    • G02B1/043Contact lenses
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40High-molecular-weight compounds
    • C08G18/48Polyethers
    • C08G18/50Polyethers having heteroatoms other than oxygen
    • C08G18/5003Polyethers having heteroatoms other than oxygen having halogens
    • C08G18/5015Polyethers having heteroatoms other than oxygen having halogens having fluorine atoms
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/70Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
    • C08G18/81Unsaturated isocyanates or isothiocyanates
    • C08G18/8108Unsaturated isocyanates or isothiocyanates having only one isocyanate or isothiocyanate group
    • C08G18/8116Unsaturated isocyanates or isothiocyanates having only one isocyanate or isothiocyanate group esters of acrylic or alkylacrylic acid having only one isocyanate or isothiocyanate group
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/002Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from unsaturated compounds
    • C08G65/005Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from unsaturated compounds containing halogens
    • C08G65/007Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from unsaturated compounds containing halogens containing fluorine
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02Polyalkylene oxides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • General Physics & Mathematics (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
  • Polyethers (AREA)
  • Graft Or Block Polymers (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Materials For Medical Uses (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
AT99948749T 1998-09-15 1999-09-13 Perfluoroalkylpolyetherpolymere für ophthalmische anwendungen ATE356157T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98117421 1998-09-15

Publications (1)

Publication Number Publication Date
ATE356157T1 true ATE356157T1 (de) 2007-03-15

Family

ID=8232633

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99948749T ATE356157T1 (de) 1998-09-15 1999-09-13 Perfluoroalkylpolyetherpolymere für ophthalmische anwendungen

Country Status (14)

Country Link
US (1) US6225367B1 (https=)
EP (1) EP1161476B1 (https=)
JP (1) JP2002524628A (https=)
CN (1) CN1318076A (https=)
AT (1) ATE356157T1 (https=)
AU (1) AU754125C (https=)
BR (1) BR9913694A (https=)
CA (1) CA2343159C (https=)
DE (1) DE69935457T2 (https=)
ES (1) ES2284268T3 (https=)
NO (1) NO20011292L (https=)
TW (1) TWI230712B (https=)
WO (1) WO2000015686A1 (https=)
ZA (1) ZA200102072B (https=)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6451287B1 (en) * 2000-05-26 2002-09-17 Smithkline Beecham Corporation Fluorinated copolymer surfactants and use thereof in aerosol compositions
US6544286B1 (en) * 2000-07-18 2003-04-08 Tissue Engineering Refraction, Inc. Pre-fabricated corneal tissue lens method of corneal overlay to correct vision
US6660828B2 (en) 2001-05-14 2003-12-09 Omnova Solutions Inc. Fluorinated short carbon atom side chain and polar group containing polymer, and flow, or leveling, or wetting agents thereof
CA2447132C (en) * 2001-05-14 2008-10-07 Omnova Solutions Inc. Polymeric surfactants derived from cyclic monomers having pendant fluorinated carbon groups
US20030060878A1 (en) 2001-08-31 2003-03-27 Shadduck John H. Intraocular lens system and method for power adjustment
CA2473703A1 (en) 2002-01-17 2003-07-31 Edward Perez Methods for producing epithelial flaps on the cornea and for placement of ocular devices and lenses beneath an epithelial flap or membrane, epithelial delaminating devices, and structures of epithelium and ocular devices and lenses
US7261737B2 (en) * 2002-12-12 2007-08-28 Powervision, Inc. Accommodating intraocular lens system and method
US8048155B2 (en) 2002-02-02 2011-11-01 Powervision, Inc. Intraocular implant devices
US7122053B2 (en) * 2002-12-12 2006-10-17 Powervision, Inc. Accommodating intraocular lens system and method
US6935743B2 (en) * 2002-02-06 2005-08-30 John H. Shadduck Adaptive optic lens and method of making
AU2002309806A1 (en) * 2002-04-10 2003-10-27 Honeywell International, Inc. New porogens for porous silica dielectric for integral circuit applications
JP4662718B2 (ja) * 2002-04-10 2011-03-30 ハネウェル・インターナショナル・インコーポレーテッド 集積回路用途用の低金属多孔質シリカ誘電体
EP1364663A1 (en) * 2002-05-21 2003-11-26 Commonwealth Scientific And Industrial Research Organisation Ocular devices with functionalized surface with adhesive properties
US20060034807A1 (en) * 2002-08-09 2006-02-16 Ottawa Health Research Institute Innervated artificial tissues and uses thereof
US8361145B2 (en) * 2002-12-12 2013-01-29 Powervision, Inc. Accommodating intraocular lens system having circumferential haptic support and method
US7438723B2 (en) * 2002-12-12 2008-10-21 Powervision, Inc. Lens system and method for power adjustment using externally actuated micropumps
US7247168B2 (en) * 2002-12-12 2007-07-24 Powervision, Inc. Accommodating intraocular lens system and method
US7637947B2 (en) * 2002-12-12 2009-12-29 Powervision, Inc. Accommodating intraocular lens system having spherical aberration compensation and method
US8328869B2 (en) 2002-12-12 2012-12-11 Powervision, Inc. Accommodating intraocular lenses and methods of use
US10835373B2 (en) 2002-12-12 2020-11-17 Alcon Inc. Accommodating intraocular lenses and methods of use
US7217288B2 (en) * 2002-12-12 2007-05-15 Powervision, Inc. Accommodating intraocular lens having peripherally actuated deflectable surface and method
US7425601B2 (en) * 2002-12-20 2008-09-16 Exxonmobil Chemical Patents Inc. Polymers with new sequence distributions
AU2003297458A1 (en) * 2002-12-20 2004-07-22 Exxonmobil Chemical Patents Inc. Polymerization processes
DE60332866D1 (de) * 2002-12-20 2010-07-15 Exxonmobil Chem Patents Inc Polymere mit neuen sequenzverteilungen
WO2004058827A1 (en) * 2002-12-20 2004-07-15 Exxonmobil Chemical Patents Inc. Polymerization processes
US7307118B2 (en) * 2004-11-24 2007-12-11 Molecular Imprints, Inc. Composition to reduce adhesion between a conformable region and a mold
US20050271794A1 (en) * 2003-12-24 2005-12-08 Synecor, Llc Liquid perfluoropolymers and medical and cosmetic applications incorporating same
US20050142315A1 (en) * 2003-12-24 2005-06-30 Desimone Joseph M. Liquid perfluoropolymers and medical applications incorporating same
US20050273146A1 (en) * 2003-12-24 2005-12-08 Synecor, Llc Liquid perfluoropolymers and medical applications incorporating same
US8076386B2 (en) * 2004-02-23 2011-12-13 Molecular Imprints, Inc. Materials for imprint lithography
US7662892B2 (en) 2004-06-21 2010-02-16 Exxonmobil Chemical Patents Inc. Impact copolymers
WO2006009942A1 (en) * 2004-06-21 2006-01-26 Exxonmobil Chemical Patents Inc. Polymerization process
EP1765885A1 (en) * 2004-06-21 2007-03-28 Exxonmobil Chemical Patents Inc. Polymer recovery method
US7981984B2 (en) * 2004-06-21 2011-07-19 Exxonmobil Chemical Patents Inc. Polymerization process
US9872763B2 (en) 2004-10-22 2018-01-23 Powervision, Inc. Accommodating intraocular lenses
US7799882B2 (en) * 2005-06-20 2010-09-21 Exxonmobil Chemical Patents Inc. Polymerization process
US8808808B2 (en) 2005-07-22 2014-08-19 Molecular Imprints, Inc. Method for imprint lithography utilizing an adhesion primer layer
US7759407B2 (en) * 2005-07-22 2010-07-20 Molecular Imprints, Inc. Composition for adhering materials together
US8557351B2 (en) 2005-07-22 2013-10-15 Molecular Imprints, Inc. Method for adhering materials together
US20070088433A1 (en) * 2005-10-17 2007-04-19 Powervision Accommodating intraocular lens system utilizing direct force transfer from zonules and method of use
EP1801140A1 (en) * 2005-12-22 2007-06-27 Mnemoscience GmbH Macro-diacrylate
MX2008013847A (es) * 2006-05-11 2009-03-04 Air Prod & Chem Composiciones para el cuidado personal que contienen polimeros funcionalizados.
US20080110557A1 (en) * 2006-11-15 2008-05-15 Molecular Imprints, Inc. Methods and Compositions for Providing Preferential Adhesion and Release of Adjacent Surfaces
JP4912140B2 (ja) * 2006-12-26 2012-04-11 株式会社イノアックコーポレーション 紫外線硬化発泡体
US8158712B2 (en) 2007-02-21 2012-04-17 Powervision, Inc. Polymeric materials suitable for ophthalmic devices and methods of manufacture
ATE552280T1 (de) * 2007-07-19 2012-04-15 Novartis Ag Linsen und materialien mit hohem ionen- und metabolitfluss
US8968396B2 (en) 2007-07-23 2015-03-03 Powervision, Inc. Intraocular lens delivery systems and methods of use
US8314927B2 (en) 2007-07-23 2012-11-20 Powervision, Inc. Systems and methods for testing intraocular lenses
JP5426547B2 (ja) 2007-07-23 2014-02-26 パワーヴィジョン・インコーポレーテッド レンズ送出システム
EP2178463B1 (en) 2007-07-23 2013-09-04 PowerVision, Inc. Accommodating intraocular lenses
EP2178462B1 (en) 2007-07-23 2014-04-02 PowerVision, Inc. Post-implant lens power modification
US20090026924A1 (en) * 2007-07-23 2009-01-29 Leung Roger Y Methods of making low-refractive index and/or low-k organosilicate coatings
US20090098359A1 (en) * 2007-10-11 2009-04-16 Waller Jr Clinton P Hydrophilic porous substrates
MY154718A (en) * 2007-12-10 2015-07-15 Novartis Ag Method for making silicone hydrogel contact lenses
JP2009168875A (ja) * 2008-01-11 2009-07-30 Mo-Wei Hung シリコンコンタクトレンズの成型方法とその構造
CN102112524B (zh) * 2008-08-08 2013-02-27 Dic株式会社 含氟化合物以及使用其的活性能量射线固化型树脂组合物
US10299913B2 (en) 2009-01-09 2019-05-28 Powervision, Inc. Accommodating intraocular lenses and methods of use
EP2435506B1 (en) * 2009-05-25 2014-04-02 Solvay Specialty Polymers Italy S.p.A. Protective film for a solar cell module
US8394870B2 (en) * 2009-07-16 2013-03-12 E.I. Du Pont De Nemours And Company Crosslinked fluoropolymer networks
WO2011026068A2 (en) 2009-08-31 2011-03-03 Powervision, Inc. Lens capsule size estimation
US9233063B2 (en) * 2009-12-17 2016-01-12 Air Products And Chemicals, Inc. Polymeric compositions for personal care products
US9138308B2 (en) 2010-02-03 2015-09-22 Apollo Endosurgery, Inc. Mucosal tissue adhesion via textured surface
US8900298B2 (en) 2010-02-23 2014-12-02 Powervision, Inc. Fluid for accommodating intraocular lenses
JP5852640B2 (ja) 2010-05-11 2016-02-03 アラーガン、インコーポレイテッドAllergan,Incorporated ポロゲン組成物、製造方法、および使用
WO2012006616A2 (en) 2010-07-09 2012-01-12 Powervision, Inc. Intraocular lens delivery devices and methods of use
JP6071995B2 (ja) 2011-03-24 2017-02-01 パワーヴィジョン・インコーポレーテッド 眼内レンズ装填システムおよび使用方法
WO2013017470A1 (en) 2011-08-04 2013-02-07 Solvay Specialty Polymers Italy S.P.A. Compositions of ionisable fluoropolymers
US10433949B2 (en) 2011-11-08 2019-10-08 Powervision, Inc. Accommodating intraocular lenses
WO2014022657A1 (en) 2012-08-02 2014-02-06 Allergan, Inc. Mucosal tissue adhesion via textured surface
EP2900289A1 (en) 2012-09-28 2015-08-05 Allergan, Inc. Porogen compositions, methods of making and uses
ES2834479T3 (es) 2013-03-15 2021-06-17 Alcon Inc Método para reconfigurar una lente intraocular para su entrega a un dispositivo de entrega
EP3221382B1 (en) 2014-11-19 2020-05-06 Solvay Specialty Polymers Italy S.p.A. Zwitterionic derivatives of (per)fluoropolyethers
CN108348328B (zh) 2015-11-06 2020-04-10 力景公司 可调节人工晶状体和制造方法
JP7319349B2 (ja) * 2018-08-16 2023-08-01 テルモ株式会社 細胞培養基材
JP7315652B2 (ja) * 2018-08-16 2023-07-26 テルモ株式会社 細胞培養基材
US12404485B2 (en) 2018-12-20 2025-09-02 Terumo Kabushiki Kaisha Cell culture substrate
CN114650789B (zh) 2019-10-04 2025-09-26 爱尔康公司 可调节眼内透镜及术后调节眼内透镜的方法
BR112023018612A2 (pt) 2021-04-06 2023-10-24 Alcon Inc Aparelho, sistemas e métodos para avaliar objetivamente a acomodação em um olho
US12245930B2 (en) 2023-06-30 2025-03-11 Alcon Inc. System and methods for compensating for intraocular lens tilt

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE392582B (sv) * 1970-05-21 1977-04-04 Gore & Ass Forfarande vid framstellning av ett porost material, genom expandering och streckning av en tetrafluoretenpolymer framstelld i ett pastabildande strengsprutningsforfarande
US4818801A (en) * 1982-01-18 1989-04-04 Minnesota Mining And Manufacturing Company Ophthalmic device comprising a polymer of a telechelic perfluoropolyether
US4440918A (en) * 1982-01-18 1984-04-03 Minnesota Mining And Manufacturing Company Contact lens containing a fluorinated telechelic polyether
US4799931A (en) * 1986-05-14 1989-01-24 Lindstrom Richard L Intracorneal lens
JP2550036B2 (ja) * 1986-11-21 1996-10-30 株式会社メニコン コンタクトレンズ用液剤組成物
US5244799A (en) * 1987-05-20 1993-09-14 Anderson David M Preparation of a polymeric hydrogel containing micropores and macropores for use as a cell culture substrate
US5238613A (en) * 1987-05-20 1993-08-24 Anderson David M Microporous materials
JPH04239504A (ja) * 1991-01-22 1992-08-27 Yokohama Rubber Co Ltd:The 光硬化型ゲル基材
ES2150723T3 (es) * 1991-07-05 2000-12-01 Biocompatibles Ltd Recubrimientos de superficie polimericos.
ES2144419T3 (es) * 1991-07-05 2000-06-16 Biocompatibles Ltd Revestimientos polimericos de superficies.
IT1251487B (it) * 1991-09-17 1995-05-15 Syremont Spa Dispersioni acquose di poliuretani fluorurati
JP3165992B2 (ja) * 1995-03-14 2001-05-14 東レ株式会社 抗菌性樹脂とその製造方法及び抗菌性繊維構造物
KR19980703533A (ko) * 1995-04-04 1998-11-05 발덱베르너 세포 성장 기질 중합체
AUPN215995A0 (en) * 1995-04-04 1995-04-27 Ciba-Geigy Ag Novel materials
AUPN354595A0 (en) 1995-06-14 1995-07-06 Ciba-Geigy Ag Novel materials
CN1214055A (zh) 1996-03-04 1999-04-14 埃克森化学专利公司 稳定的金属茂催化剂体系
ATE254641T1 (de) * 1996-03-27 2003-12-15 Commw Scient Ind Res Org Poröses polymer mit hohem wassergehalt
US6060530A (en) 1996-04-04 2000-05-09 Novartis Ag Process for manufacture of a porous polymer by use of a porogen

Also Published As

Publication number Publication date
BR9913694A (pt) 2001-06-05
NO20011292D0 (no) 2001-03-14
AU754125B2 (en) 2002-11-07
CA2343159A1 (en) 2000-03-23
AU754125C (en) 2006-08-31
CN1318076A (zh) 2001-10-17
ES2284268T3 (es) 2007-11-01
WO2000015686A1 (en) 2000-03-23
EP1161476B1 (en) 2007-03-07
JP2002524628A (ja) 2002-08-06
NO20011292L (no) 2001-05-14
DE69935457T2 (de) 2007-11-15
ZA200102072B (en) 2001-10-30
US6225367B1 (en) 2001-05-01
AU6190699A (en) 2000-04-03
EP1161476A1 (en) 2001-12-12
CA2343159C (en) 2010-06-22
TWI230712B (en) 2005-04-11
DE69935457D1 (de) 2007-04-19

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