ATE348168T1 - Mutierte formen des meningococcen-adp- ribosylierenden toxins - Google Patents
Mutierte formen des meningococcen-adp- ribosylierenden toxinsInfo
- Publication number
- ATE348168T1 ATE348168T1 AT03748401T AT03748401T ATE348168T1 AT E348168 T1 ATE348168 T1 AT E348168T1 AT 03748401 T AT03748401 T AT 03748401T AT 03748401 T AT03748401 T AT 03748401T AT E348168 T1 ATE348168 T1 AT E348168T1
- Authority
- AT
- Austria
- Prior art keywords
- adp
- glu
- meningococc
- mutated forms
- ribosylating toxin
- Prior art date
Links
- 239000003053 toxin Substances 0.000 title abstract 3
- 231100000765 toxin Toxicity 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108700012359 toxins Proteins 0.000 abstract 2
- 102000009062 ADP Ribose Transferases Human genes 0.000 abstract 1
- 108010049290 ADP Ribose Transferases Proteins 0.000 abstract 1
- 102000002250 NAD+ Nucleosidase Human genes 0.000 abstract 1
- 108010000193 NAD+ Nucleosidase Proteins 0.000 abstract 1
- 241000588650 Neisseria meningitidis Species 0.000 abstract 1
- 230000035772 mutation Effects 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1077—Pentosyltransferases (2.4.2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2497—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing N- glycosyl compounds (3.2.2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/02—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2) hydrolysing N-glycosyl compounds (3.2.2)
- C12Y302/02005—NAD+ nucleosidase (3.2.2.5)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55544—Bacterial toxins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Mycology (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0220205.9A GB0220205D0 (en) | 2002-08-30 | 2002-08-30 | Neisseria toxin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE348168T1 true ATE348168T1 (de) | 2007-01-15 |
Family
ID=9943245
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03748401T ATE348168T1 (de) | 2002-08-30 | 2003-09-01 | Mutierte formen des meningococcen-adp- ribosylierenden toxins |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7858096B2 (de) |
| EP (1) | EP1534836B1 (de) |
| AT (1) | ATE348168T1 (de) |
| AU (1) | AU2003268624A1 (de) |
| CA (1) | CA2497279C (de) |
| CY (1) | CY1107573T1 (de) |
| DE (1) | DE60310416T2 (de) |
| GB (1) | GB0220205D0 (de) |
| WO (1) | WO2004020634A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10212721A1 (de) * | 2001-03-24 | 2002-09-26 | Marquardt Gmbh | Ansteuereinrichtung für einen Elektromotor |
| GB0108024D0 (en) | 2001-03-30 | 2001-05-23 | Chiron Spa | Bacterial toxins |
| JP7179464B2 (ja) | 2015-01-20 | 2022-11-29 | アイジーエム バイオサイエンシズ インコーポレイテッド | 腫瘍壊死因子 （ｔｎｆ） スーパーファミリー受容体結合分子およびその使用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9326174D0 (en) | 1993-12-22 | 1994-02-23 | Biocine Sclavo | Mucosal adjuvant |
| MXPA01003557A (es) | 1998-10-09 | 2004-04-05 | Chiron Corp | Secuencias genomicas de neisseria y metodos para su uso. |
| US7115730B1 (en) | 1999-04-27 | 2006-10-03 | Chiron Srl | Immunogenic detoxified mutant E. coli LT-A-toxin |
| GB0108024D0 (en) * | 2001-03-30 | 2001-05-23 | Chiron Spa | Bacterial toxins |
-
2002
- 2002-08-30 GB GBGB0220205.9A patent/GB0220205D0/en not_active Ceased
-
2003
- 2003-09-01 US US10/526,125 patent/US7858096B2/en not_active Expired - Fee Related
- 2003-09-01 EP EP03748401A patent/EP1534836B1/de not_active Expired - Lifetime
- 2003-09-01 AU AU2003268624A patent/AU2003268624A1/en not_active Abandoned
- 2003-09-01 WO PCT/IB2003/004295 patent/WO2004020634A1/en not_active Ceased
- 2003-09-01 DE DE60310416T patent/DE60310416T2/de not_active Expired - Lifetime
- 2003-09-01 AT AT03748401T patent/ATE348168T1/de active
- 2003-09-01 CA CA2497279A patent/CA2497279C/en not_active Expired - Fee Related
-
2007
- 2007-03-01 CY CY20071100287T patent/CY1107573T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CY1107573T1 (el) | 2013-03-13 |
| EP1534836B1 (de) | 2006-12-13 |
| DE60310416D1 (de) | 2007-01-25 |
| US20060269563A1 (en) | 2006-11-30 |
| GB0220205D0 (en) | 2002-10-09 |
| US7858096B2 (en) | 2010-12-28 |
| AU2003268624A1 (en) | 2004-03-19 |
| CA2497279A1 (en) | 2004-03-11 |
| DE60310416T2 (de) | 2007-09-27 |
| EP1534836A1 (de) | 2005-06-01 |
| CA2497279C (en) | 2013-02-19 |
| WO2004020634A1 (en) | 2004-03-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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