ATE347355T1 - Polycyclische dianthrachinone als antikrebsmittel und antiangiogenesemittel - Google Patents

Polycyclische dianthrachinone als antikrebsmittel und antiangiogenesemittel

Info

Publication number
ATE347355T1
ATE347355T1 AT01902613T AT01902613T ATE347355T1 AT E347355 T1 ATE347355 T1 AT E347355T1 AT 01902613 T AT01902613 T AT 01902613T AT 01902613 T AT01902613 T AT 01902613T AT E347355 T1 ATE347355 T1 AT E347355T1
Authority
AT
Austria
Prior art keywords
hydroxy
alkyl
alkoxy
hydrogen
independently selected
Prior art date
Application number
AT01902613T
Other languages
English (en)
Inventor
Yehuda Mazur
Gad Lavie
Original Assignee
Yeda Res & Dev
Univ New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/494,296 external-priority patent/US6229048B1/en
Application filed by Yeda Res & Dev, Univ New York filed Critical Yeda Res & Dev
Application granted granted Critical
Publication of ATE347355T1 publication Critical patent/ATE347355T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT01902613T 2000-01-31 2001-01-31 Polycyclische dianthrachinone als antikrebsmittel und antiangiogenesemittel ATE347355T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/494,296 US6229048B1 (en) 1997-07-31 2000-01-31 Helianthrone derivatives as anti-cancer agents

Publications (1)

Publication Number Publication Date
ATE347355T1 true ATE347355T1 (de) 2006-12-15

Family

ID=23963894

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01902613T ATE347355T1 (de) 2000-01-31 2001-01-31 Polycyclische dianthrachinone als antikrebsmittel und antiangiogenesemittel

Country Status (9)

Country Link
US (2) US6867235B2 (de)
EP (1) EP1313459B1 (de)
AT (1) ATE347355T1 (de)
AU (1) AU3047001A (de)
CA (1) CA2396704A1 (de)
DE (1) DE60125048T2 (de)
ES (1) ES2275647T3 (de)
IL (1) IL150457A0 (de)
WO (1) WO2001056558A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001056558A1 (en) * 2000-01-31 2001-08-09 Yeda Research And Development Co. Ltd. Polycyclic dianthraquinones as anti-cancer and anti-angiogenic agents
DE10261825A1 (de) * 2002-12-20 2004-07-01 Charité - Universitätsmedizin Berlin (Charité) Verwendung von Hypericin und/oder dessen Derivaten zur Tumorprävention
US7553326B2 (en) * 2003-11-24 2009-06-30 Sweet Richard M Method and apparatus for preventing dialysis graft intimal hyperplasia
EP2571507B1 (de) 2010-05-04 2017-01-04 Soligenix, Inc. Formulierungen und verfahren zur behandlung von hauterkrankungen
JP6890616B2 (ja) 2016-03-01 2021-06-18 ソリジェニックス インコーポレーテッド 合成ハイペリシンを製造するためのシステムおよび方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL93682A (en) * 1989-03-16 1996-06-18 Yeda Res & Dev Polycyclic compounds with antigypical activity are used in the manufacture of medicines and pharmaceutical preparations containing them
DE4239959A1 (de) * 1992-11-27 1994-06-01 Schwabe Willmar Gmbh & Co Johanniskraut-Trockenextrakt, Verfahren zu seiner Herstellung und seine Verwendung
US5824654A (en) * 1994-09-02 1998-10-20 New York University Method for delivery of nucleic acids to cells using hypericin polyamine complexes
WO1997004761A1 (en) * 1995-07-28 1997-02-13 Trustees Of Boston University Methods and compositions for treating cell proliferative disorders
IL121440A0 (en) * 1997-07-31 1998-01-04 Yeda Res & Dev The use of 1,3,4,6-tetrahydroxy-helianthrone and its derivatives in photodynamic therapy and certain such novel derivatives
WO2001056558A1 (en) * 2000-01-31 2001-08-09 Yeda Research And Development Co. Ltd. Polycyclic dianthraquinones as anti-cancer and anti-angiogenic agents

Also Published As

Publication number Publication date
ES2275647T3 (es) 2007-06-16
DE60125048T2 (de) 2007-07-12
EP1313459A1 (de) 2003-05-28
AU3047001A (en) 2001-08-14
US6867235B2 (en) 2005-03-15
IL150457A0 (en) 2002-12-01
US20030105357A1 (en) 2003-06-05
CA2396704A1 (en) 2001-08-09
DE60125048D1 (de) 2007-01-18
EP1313459B1 (de) 2006-12-06
US20050038115A1 (en) 2005-02-17
WO2001056558A1 (en) 2001-08-09

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties