ATE344089T1 - 2-amino-6-(2,4,5-substituierte-phenyl)-pyridine zur verwendung als stickoxid-synthase-hemmer - Google Patents
2-amino-6-(2,4,5-substituierte-phenyl)-pyridine zur verwendung als stickoxid-synthase-hemmerInfo
- Publication number
- ATE344089T1 ATE344089T1 AT02775016T AT02775016T ATE344089T1 AT E344089 T1 ATE344089 T1 AT E344089T1 AT 02775016 T AT02775016 T AT 02775016T AT 02775016 T AT02775016 T AT 02775016T AT E344089 T1 ATE344089 T1 AT E344089T1
- Authority
- AT
- Austria
- Prior art keywords
- pyridines
- phenyl
- amino
- substituted
- nitrogen oxide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P25/04—Centrally acting analgesics, e.g. opioids
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/36—Opioid-abuse
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P31/04—Antibacterial agents
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Ophthalmology & Optometry (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US32825301P | 2001-10-10 | 2001-10-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE344089T1 true ATE344089T1 (de) | 2006-11-15 |
Family
ID=23280189
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02775016T ATE344089T1 (de) | 2001-10-10 | 2002-09-24 | 2-amino-6-(2,4,5-substituierte-phenyl)-pyridine zur verwendung als stickoxid-synthase-hemmer |
Country Status (36)
Country | Link |
---|---|
EP (1) | EP1434624B1 (de) |
JP (1) | JP2005506337A (de) |
KR (1) | KR20040053157A (de) |
CN (1) | CN1568207A (de) |
AP (1) | AP2004003003A0 (de) |
AR (1) | AR036763A1 (de) |
AT (1) | ATE344089T1 (de) |
BG (1) | BG108669A (de) |
BR (1) | BR0213193A (de) |
CA (1) | CA2463364A1 (de) |
CZ (1) | CZ2004450A3 (de) |
DE (1) | DE60215837T2 (de) |
DO (1) | DOP2002000467A (de) |
EA (1) | EA007074B1 (de) |
EC (1) | ECSP045055A (de) |
EE (1) | EE200400085A (de) |
ES (1) | ES2275917T3 (de) |
GT (1) | GT200200206A (de) |
HN (1) | HN2002000289A (de) |
HR (1) | HRP20040260A2 (de) |
HU (1) | HUP0401678A3 (de) |
IL (1) | IL161089A0 (de) |
IS (1) | IS7171A (de) |
MA (1) | MA27074A1 (de) |
MX (1) | MXPA04002313A (de) |
NO (1) | NO20041411L (de) |
NZ (1) | NZ531591A (de) |
OA (1) | OA12664A (de) |
PA (1) | PA8556101A1 (de) |
PE (1) | PE20030478A1 (de) |
PL (1) | PL369454A1 (de) |
SK (1) | SK1642004A3 (de) |
TN (1) | TNSN04057A1 (de) |
UY (1) | UY27476A1 (de) |
WO (1) | WO2003030993A1 (de) |
ZA (1) | ZA200401747B (de) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030232739A1 (en) * | 2001-08-15 | 2003-12-18 | Pfizer Inc. | Pharmaceutical combinations comprising a NOS inhibitor and an NMDA receptor antagonist |
EP1850838A2 (de) * | 2005-02-21 | 2007-11-07 | Proximagen Ltd. | Hemmung oder behandlung von dyskinesie |
AU2011347718B2 (en) * | 2010-12-24 | 2016-06-23 | Msd Oss B.V. | N-substituted azetidine derivatives |
RU2637503C1 (ru) * | 2016-12-30 | 2017-12-05 | Федеральное государственное автономное образовательное учреждение высшего образования "Национальный исследовательский Томский государственный университет" (ТГУ, НИ ТГУ) | Способ получения n2-метилдезоксигуанозина |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3455229B2 (ja) * | 1996-03-29 | 2003-10-14 | ファイザー インク. | 6―フェニルピリジル―2―アミン誘導体 |
HUP0000762A3 (en) * | 1997-02-10 | 2000-10-30 | Pfizer Prod Inc | 2-amino-6-(2-substituted-4-phenoxy)-substituted-pyridines, and pharmaceutical compositions containing them |
AP2001002326A0 (en) * | 1999-05-21 | 2001-12-31 | Pfizer Prod Inc | New pharmaceuticals combinations for nos inhibitors. |
-
2002
- 2002-09-23 DO DO2002000467A patent/DOP2002000467A/es unknown
- 2002-09-24 CZ CZ2004450A patent/CZ2004450A3/cs unknown
- 2002-09-24 BR BR0213193-5A patent/BR0213193A/pt not_active IP Right Cessation
- 2002-09-24 ES ES02775016T patent/ES2275917T3/es not_active Expired - Lifetime
- 2002-09-24 OA OA1200400093A patent/OA12664A/en unknown
- 2002-09-24 EA EA200400321A patent/EA007074B1/ru not_active IP Right Cessation
- 2002-09-24 PL PL02369454A patent/PL369454A1/xx not_active Application Discontinuation
- 2002-09-24 AT AT02775016T patent/ATE344089T1/de not_active IP Right Cessation
- 2002-09-24 EP EP02775016A patent/EP1434624B1/de not_active Expired - Lifetime
- 2002-09-24 EE EEP200400085A patent/EE200400085A/xx unknown
- 2002-09-24 CA CA002463364A patent/CA2463364A1/en not_active Abandoned
- 2002-09-24 DE DE60215837T patent/DE60215837T2/de not_active Expired - Fee Related
- 2002-09-24 KR KR10-2004-7005248A patent/KR20040053157A/ko not_active Application Discontinuation
- 2002-09-24 JP JP2003534022A patent/JP2005506337A/ja not_active Withdrawn
- 2002-09-24 AP APAP/P/2004/003003A patent/AP2004003003A0/en unknown
- 2002-09-24 HU HU0401678A patent/HUP0401678A3/hu unknown
- 2002-09-24 IL IL16108902A patent/IL161089A0/xx unknown
- 2002-09-24 CN CNA028200675A patent/CN1568207A/zh active Pending
- 2002-09-24 NZ NZ531591A patent/NZ531591A/en unknown
- 2002-09-24 SK SK164-2004A patent/SK1642004A3/sk not_active Application Discontinuation
- 2002-09-24 WO PCT/IB2002/003939 patent/WO2003030993A1/en active IP Right Grant
- 2002-09-24 MX MXPA04002313A patent/MXPA04002313A/es active IP Right Grant
- 2002-10-04 PE PE2002000987A patent/PE20030478A1/es not_active Application Discontinuation
- 2002-10-08 UY UY27476A patent/UY27476A1/es not_active Application Discontinuation
- 2002-10-08 AR ARP020103790A patent/AR036763A1/es unknown
- 2002-10-09 HN HN2002000289A patent/HN2002000289A/es unknown
- 2002-10-10 GT GT200200206A patent/GT200200206A/es unknown
- 2002-10-10 PA PA20028556101A patent/PA8556101A1/es unknown
-
2004
- 2004-03-03 ZA ZA200401747A patent/ZA200401747B/en unknown
- 2004-03-04 IS IS7171A patent/IS7171A/is unknown
- 2004-03-17 HR HRP20040260 patent/HRP20040260A2/hr not_active Application Discontinuation
- 2004-04-02 NO NO20041411A patent/NO20041411L/no unknown
- 2004-04-06 BG BG108669A patent/BG108669A/xx unknown
- 2004-04-07 TN TNP2004000057A patent/TNSN04057A1/fr unknown
- 2004-04-08 EC EC2004005055A patent/ECSP045055A/es unknown
- 2004-04-08 MA MA27619A patent/MA27074A1/fr unknown
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