NO20041411L - 2-amino-6-(2,4,5 -substituerte-fenyl)-pyridiner for anvendelse som nitrogenoksyd syntase inhibitorer - Google Patents

2-amino-6-(2,4,5 -substituerte-fenyl)-pyridiner for anvendelse som nitrogenoksyd syntase inhibitorer

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Publication number
NO20041411L
NO20041411L NO20041411A NO20041411A NO20041411L NO 20041411 L NO20041411 L NO 20041411L NO 20041411 A NO20041411 A NO 20041411A NO 20041411 A NO20041411 A NO 20041411A NO 20041411 L NO20041411 L NO 20041411L
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NO
Norway
Prior art keywords
phenyl
pyridin
methoxy
ethyl
nitric oxide
Prior art date
Application number
NO20041411A
Other languages
English (en)
Inventor
Iii John Adams Lowe
Robert Alfred Volkmann
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of NO20041411L publication Critical patent/NO20041411L/no

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    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/73Unsubstituted amino or imino radicals
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

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Abstract

Det er beskrevet forbindelsene 6-[4-(N-metyl-3azetidinoksy)-5-etyl-2-metoksy-fenyl]-pyridin-2-ylamin, 6- [4-(N,N-dimetyIaniinometyl)-5 -etyl-2-metoksy-fenyl] -pyridin-2-ylamin, 6- [4-(N-metyllaminometyi)-5-ety 1-2-metoksy-fenyl]-pyridin-2-ylamin, 6-[4-(3-azetidinoksy)-5-etyl-2-metoksy-fenyl]-pyridin2-ylamin og 6-[4(2-dimetylamino-etoksy)-5-etyl-2-metoksy-fenyl]-pyridin-2-ylaniin, og farmasøytisk akseptable salter derav, farmasøytiske sammensetninger inneholdende slike forbindelser og anvendelser av slike forbindelser som nitrogenoksidsyntaseinhibitorer ved behandling og forebygging av sentralnervesystemet og andre forstyrrelser.
NO20041411A 2001-10-10 2004-04-02 2-amino-6-(2,4,5 -substituerte-fenyl)-pyridiner for anvendelse som nitrogenoksyd syntase inhibitorer NO20041411L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32825301P 2001-10-10 2001-10-10
PCT/IB2002/003939 WO2003030993A1 (en) 2001-10-10 2002-09-24 2-amino-6-(2,4,5-substituted-phenyl)-pyridines for use as nitric oxide synthase inhibitors

Publications (1)

Publication Number Publication Date
NO20041411L true NO20041411L (no) 2004-04-02

Family

ID=23280189

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20041411A NO20041411L (no) 2001-10-10 2004-04-02 2-amino-6-(2,4,5 -substituerte-fenyl)-pyridiner for anvendelse som nitrogenoksyd syntase inhibitorer

Country Status (36)

Country Link
EP (1) EP1434624B1 (no)
JP (1) JP2005506337A (no)
KR (1) KR20040053157A (no)
CN (1) CN1568207A (no)
AP (1) AP2004003003A0 (no)
AR (1) AR036763A1 (no)
AT (1) ATE344089T1 (no)
BG (1) BG108669A (no)
BR (1) BR0213193A (no)
CA (1) CA2463364A1 (no)
CZ (1) CZ2004450A3 (no)
DE (1) DE60215837T2 (no)
DO (1) DOP2002000467A (no)
EA (1) EA007074B1 (no)
EC (1) ECSP045055A (no)
EE (1) EE200400085A (no)
ES (1) ES2275917T3 (no)
GT (1) GT200200206A (no)
HN (1) HN2002000289A (no)
HR (1) HRP20040260A2 (no)
HU (1) HUP0401678A3 (no)
IL (1) IL161089A0 (no)
IS (1) IS7171A (no)
MA (1) MA27074A1 (no)
MX (1) MXPA04002313A (no)
NO (1) NO20041411L (no)
NZ (1) NZ531591A (no)
OA (1) OA12664A (no)
PA (1) PA8556101A1 (no)
PE (1) PE20030478A1 (no)
PL (1) PL369454A1 (no)
SK (1) SK1642004A3 (no)
TN (1) TNSN04057A1 (no)
UY (1) UY27476A1 (no)
WO (1) WO2003030993A1 (no)
ZA (1) ZA200401747B (no)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030232739A1 (en) * 2001-08-15 2003-12-18 Pfizer Inc. Pharmaceutical combinations comprising a NOS inhibitor and an NMDA receptor antagonist
EP1850838A2 (en) * 2005-02-21 2007-11-07 Proximagen Ltd. Inhibition or treatment of dyskinesia
AU2011347718B2 (en) * 2010-12-24 2016-06-23 Msd Oss B.V. N-substituted azetidine derivatives
RU2637503C1 (ru) * 2016-12-30 2017-12-05 Федеральное государственное автономное образовательное учреждение высшего образования "Национальный исследовательский Томский государственный университет" (ТГУ, НИ ТГУ) Способ получения n2-метилдезоксигуанозина

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3455229B2 (ja) * 1996-03-29 2003-10-14 ファイザー インク. 6―フェニルピリジル―2―アミン誘導体
HUP0000762A3 (en) * 1997-02-10 2000-10-30 Pfizer Prod Inc 2-amino-6-(2-substituted-4-phenoxy)-substituted-pyridines, and pharmaceutical compositions containing them
AP2001002326A0 (en) * 1999-05-21 2001-12-31 Pfizer Prod Inc New pharmaceuticals combinations for nos inhibitors.

Also Published As

Publication number Publication date
ECSP045055A (es) 2004-05-28
EP1434624B1 (en) 2006-11-02
EA200400321A1 (ru) 2004-08-26
MXPA04002313A (es) 2005-04-08
PA8556101A1 (es) 2003-07-28
DE60215837T2 (de) 2007-05-16
EE200400085A (et) 2004-08-16
UY27476A1 (es) 2003-05-30
SK1642004A3 (sk) 2005-04-01
CA2463364A1 (en) 2003-04-17
AP2004003003A0 (en) 2004-03-31
EP1434624A1 (en) 2004-07-07
HRP20040260A2 (en) 2004-12-31
HN2002000289A (es) 2002-12-03
TNSN04057A1 (fr) 2006-06-01
ZA200401747B (en) 2005-03-03
GT200200206A (es) 2003-05-23
CZ2004450A3 (cs) 2005-03-16
BR0213193A (pt) 2004-08-31
HUP0401678A3 (en) 2007-05-02
JP2005506337A (ja) 2005-03-03
PL369454A1 (en) 2005-04-18
BG108669A (en) 2005-03-31
PE20030478A1 (es) 2003-06-06
ES2275917T3 (es) 2007-06-16
IS7171A (is) 2004-03-04
ATE344089T1 (de) 2006-11-15
KR20040053157A (ko) 2004-06-23
IL161089A0 (en) 2004-08-31
CN1568207A (zh) 2005-01-19
OA12664A (en) 2006-06-19
NZ531591A (en) 2006-04-28
DE60215837D1 (de) 2006-12-14
EA007074B1 (ru) 2006-06-30
AR036763A1 (es) 2004-09-29
WO2003030993A1 (en) 2003-04-17
DOP2002000467A (es) 2003-04-15
MA27074A1 (fr) 2004-12-20
HUP0401678A2 (hu) 2004-12-28

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NO20041411L (no) 2-amino-6-(2,4,5 -substituerte-fenyl)-pyridiner for anvendelse som nitrogenoksyd syntase inhibitorer