ATE338571T1 - Verfahren zur oberflächenmodifizierung - Google Patents
Verfahren zur oberflächenmodifizierungInfo
- Publication number
- ATE338571T1 ATE338571T1 AT02704264T AT02704264T ATE338571T1 AT E338571 T1 ATE338571 T1 AT E338571T1 AT 02704264 T AT02704264 T AT 02704264T AT 02704264 T AT02704264 T AT 02704264T AT E338571 T1 ATE338571 T1 AT E338571T1
- Authority
- AT
- Austria
- Prior art keywords
- reactive gas
- surface modification
- modifying
- plasma
- quenching
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 238000012986 modification Methods 0.000 title 1
- 230000004048 modification Effects 0.000 title 1
- 238000010791 quenching Methods 0.000 abstract 1
- 230000000171 quenching effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
- A61L33/0094—Physical treatment, e.g. plasma treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
- A61L33/0005—Use of materials characterised by their function or physical properties
- A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
- A61L33/0029—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate using an intermediate layer of polymer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
- A61L33/0076—Chemical modification of the substrate
- A61L33/0088—Chemical modification of the substrate by grafting of a monomer onto the substrate
-
- C—CHEMISTRY; METALLURGY
- C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
- C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
- C23C16/00—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes
- C23C16/02—Pretreatment of the material to be coated
- C23C16/0227—Pretreatment of the material to be coated by cleaning or etching
- C23C16/0245—Pretreatment of the material to be coated by cleaning or etching by etching with a plasma
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Surgery (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Physics & Mathematics (AREA)
- Materials Engineering (AREA)
- Plasma & Fusion (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mechanical Engineering (AREA)
- Metallurgy (AREA)
- Organic Chemistry (AREA)
- Materials For Medical Uses (AREA)
- Treatments Of Macromolecular Shaped Articles (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Polishing Bodies And Polishing Tools (AREA)
- Superconductors And Manufacturing Methods Therefor (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/772,908 US6632470B2 (en) | 2001-01-31 | 2001-01-31 | Methods for surface modification |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE338571T1 true ATE338571T1 (de) | 2006-09-15 |
Family
ID=25096592
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02704264T ATE338571T1 (de) | 2001-01-31 | 2002-01-30 | Verfahren zur oberflächenmodifizierung |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US6632470B2 (de) |
| EP (1) | EP1355686B1 (de) |
| JP (1) | JP2004524081A (de) |
| AT (1) | ATE338571T1 (de) |
| AU (1) | AU2002237956B2 (de) |
| CA (1) | CA2435962A1 (de) |
| DE (1) | DE60214513T2 (de) |
| WO (1) | WO2002060509A1 (de) |
Families Citing this family (76)
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|---|---|---|---|---|
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| US6196230B1 (en) * | 1998-09-10 | 2001-03-06 | Percardia, Inc. | Stent delivery system and method of use |
| EP1669042A3 (de) * | 1998-09-10 | 2006-06-28 | Percardia, Inc. | TMR Vorrichtung |
| US6290728B1 (en) | 1998-09-10 | 2001-09-18 | Percardia, Inc. | Designs for left ventricular conduit |
| EP1112041A1 (de) | 1998-09-10 | 2001-07-04 | Percardia, Inc. | Tmr vorrichtung |
| US6254564B1 (en) | 1998-09-10 | 2001-07-03 | Percardia, Inc. | Left ventricular conduit with blood vessel graft |
| US7033372B1 (en) | 1999-08-04 | 2006-04-25 | Percardia, Inc. | Corkscrew reinforced left ventricle to coronary artery channel |
| US6302892B1 (en) * | 1999-08-04 | 2001-10-16 | Percardia, Inc. | Blood flow conduit delivery system and method of use |
| US6854467B2 (en) | 2000-05-04 | 2005-02-15 | Percardia, Inc. | Methods and devices for delivering a ventricular stent |
| US6855370B2 (en) * | 2001-05-04 | 2005-02-15 | E. I. Du Pont De Nemours And Company | Fluoropolymer interlayer dielectric by chemical vapor deposition |
| US20030036698A1 (en) * | 2001-08-16 | 2003-02-20 | Robert Kohler | Interventional diagnostic catheter and a method for using a catheter to access artificial cardiac shunts |
| US8470019B1 (en) * | 2001-11-30 | 2013-06-25 | Advanced Cardiovascular Systems, Inc. | TiNxOy modified surface for an implantable device and a method of producing the same |
| US6949118B2 (en) | 2002-01-16 | 2005-09-27 | Percardia, Inc. | Encased implant and methods |
| US7008397B2 (en) * | 2002-02-13 | 2006-03-07 | Percardia, Inc. | Cardiac implant and methods |
| US20030211371A1 (en) * | 2002-05-09 | 2003-11-13 | Pan Alfred I-Tsung | Fuel delivery system and method of use thereof |
| US20030216801A1 (en) * | 2002-05-17 | 2003-11-20 | Heartstent Corporation | Transmyocardial implant with natural vessel graft and method |
| US20030220661A1 (en) * | 2002-05-21 | 2003-11-27 | Heartstent Corporation | Transmyocardial implant delivery system |
| US7326219B2 (en) | 2002-09-09 | 2008-02-05 | Wilk Patent Development | Device for placing transmyocardial implant |
| GB0225197D0 (en) * | 2002-10-30 | 2002-12-11 | Univ Sheffield | Surface |
| US7024921B2 (en) * | 2002-11-06 | 2006-04-11 | Sutton Stephen P | Capillary devices for determination of surface characteristics and contact angles and methods for using same |
| JP2006517789A (ja) * | 2003-01-10 | 2006-08-03 | アブリンクス エン.ヴェー. | 治療用ポリペプチド、その相同物、その断片、および血小板媒介凝集の調節での使用 |
| US20040147868A1 (en) * | 2003-01-27 | 2004-07-29 | Earl Bardsley | Myocardial implant with collar |
| DE10351813B4 (de) * | 2003-10-30 | 2006-04-13 | Leibniz-Institut Für Polymerforschung Dresden E.V. | Radikalisch gekoppelte PTFE-Polymer-Pulver und Verfahren zu ihrer Herstellung |
| DE102004011293A1 (de) * | 2004-03-09 | 2005-09-22 | Aesculap Ag & Co. Kg | Antimikrobielles medizintechnisches Produkt |
| US7276283B2 (en) | 2004-03-24 | 2007-10-02 | Wisconsin Alumni Research Foundation | Plasma-enhanced functionalization of carbon-containing substrates |
| US7723126B2 (en) * | 2004-03-24 | 2010-05-25 | Wisconsin Alumni Research Foundation | Plasma-enhanced functionalization of inorganic oxide surfaces |
| US20060122694A1 (en) * | 2004-12-03 | 2006-06-08 | Stinson Jonathan S | Medical devices and methods of making the same |
| DE102005003632A1 (de) | 2005-01-20 | 2006-08-17 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Katheter für die transvaskuläre Implantation von Herzklappenprothesen |
| US8071155B2 (en) * | 2005-05-05 | 2011-12-06 | Boston Scientific Scimed, Inc. | Medical devices and methods of making the same |
| US20060285997A1 (en) * | 2005-06-17 | 2006-12-21 | Veeco Instruments, Inc. | Plasma-modified surfaces for atomic force microscopy |
| US20070038292A1 (en) * | 2005-08-09 | 2007-02-15 | Moise Danielpour | Bio-absorbable stent |
| US7597924B2 (en) * | 2005-08-18 | 2009-10-06 | Boston Scientific Scimed, Inc. | Surface modification of ePTFE and implants using the same |
| US7845351B2 (en) * | 2005-08-31 | 2010-12-07 | Kimberly-Clark Worldwide Inc. | Germicidal face mask |
| WO2007031101A1 (de) * | 2005-09-15 | 2007-03-22 | Aesculap Ag & Co. Kg | Bioverträgliches antimikrobielles filamentmaterial |
| US20100062035A1 (en) * | 2005-09-15 | 2010-03-11 | Aesculap Ag & Co. Kg | Biocompatible Antimicrobial Filament Material |
| US20070193205A1 (en) * | 2006-01-31 | 2007-08-23 | Nathanael Hill | Method of modifying the surface of a fenestration member |
| US20080138374A1 (en) * | 2006-02-27 | 2008-06-12 | Storey Daniel M | Molecular Plasma Deposition of Bioactive Small Molecules |
| US7250195B1 (en) | 2006-02-27 | 2007-07-31 | Ionic Fusion Corporation | Molecular plasma deposition of colloidal materials |
| US8029902B2 (en) * | 2006-12-11 | 2011-10-04 | Wisconsin Alumni Research Foundation | Plasma-enhanced functionalization of substrate surfaces with quaternary ammonium and quaternary phosphonium groups |
| US20080179286A1 (en) | 2007-01-29 | 2008-07-31 | Igor Murokh | Dielectric plasma chamber apparatus and method with exterior electrodes |
| US9693841B2 (en) | 2007-04-02 | 2017-07-04 | Ension, Inc. | Surface treated staples, sutures and dental floss and methods of manufacturing the same |
| US8114465B2 (en) * | 2007-04-02 | 2012-02-14 | Ension, Inc. | Process for preparing a substrate coated with a biomolecule |
| US7896915B2 (en) | 2007-04-13 | 2011-03-01 | Jenavalve Technology, Inc. | Medical device for treating a heart valve insufficiency |
| US20090048652A1 (en) * | 2007-08-13 | 2009-02-19 | Cardiac Pacemakers, Inc | Medical device having plasma polymerized coating and method therefor |
| TWI391485B (zh) * | 2007-10-31 | 2013-04-01 | Forward Electronics Co Ltd | 生物分子固定化之方法 |
| WO2011104269A1 (en) | 2008-02-26 | 2011-09-01 | Jenavalve Technology Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
| US9044318B2 (en) | 2008-02-26 | 2015-06-02 | Jenavalve Technology Gmbh | Stent for the positioning and anchoring of a valvular prosthesis |
| US9217066B2 (en) * | 2008-03-31 | 2015-12-22 | Ford Global Technologies, Llc | Structural polymer insert and method of making the same |
| TW201229236A (en) * | 2011-01-13 | 2012-07-16 | Forward Electronics Co Ltd | Surface-modified sensor device and method for surface-modifying the same |
| EP2294118B1 (de) | 2008-05-30 | 2012-07-04 | 3M Innovative Properties Company | Verfahren zur herstellung von ligandenfunktionalisierten substraten |
| CN102186908B (zh) * | 2008-09-19 | 2013-10-16 | 3M创新有限公司 | 配体接枝官能化基材 |
| US20100174245A1 (en) * | 2009-01-08 | 2010-07-08 | Ward Dean Halverson | System for pretreating the lumen of a catheter |
| US8969473B2 (en) * | 2009-02-21 | 2015-03-03 | Sofradim Production | Compounds and medical devices activated with solvophobic linkers |
| EP2446077B1 (de) | 2009-06-23 | 2016-05-18 | 3M Innovative Properties Company | Funktionalisierter vliesartikel |
| US8377672B2 (en) | 2010-02-18 | 2013-02-19 | 3M Innovative Properties Company | Ligand functionalized polymers |
| GB201003275D0 (en) | 2010-02-26 | 2010-04-14 | Portal Medical Ltd | Method of manufacturing a medicament dispenser device |
| EP2542889B1 (de) | 2010-03-03 | 2015-03-25 | 3M Innovative Properties Company | Ligandenfunktionalisierte guanidinyl-polymere |
| US10856978B2 (en) | 2010-05-20 | 2020-12-08 | Jenavalve Technology, Inc. | Catheter system |
| WO2011147849A1 (en) | 2010-05-25 | 2011-12-01 | Jenavalve Technology Inc. | Prosthetic heart valve and transcatheter delivered endoprosthesis comprising a prosthetic heart valve and a stent |
| US8545951B2 (en) | 2012-02-29 | 2013-10-01 | Kimberly-Clark Worldwide, Inc. | Endotracheal tubes and other polymer substrates including an anti-fouling treatment |
| EP4098226A1 (de) | 2013-08-30 | 2022-12-07 | JenaValve Technology, Inc. | Endoprothese mit einem radial zusammenklappbaren rahmen und einer klappenprothese |
| ES2734581T3 (es) | 2013-12-10 | 2019-12-10 | Nova Plasma Ltd | Recipiente, aparato y método para manipular un implante |
| EP3270825B1 (de) | 2015-03-20 | 2020-04-22 | JenaValve Technology, Inc. | Herzklappenprothesenzuführsystem |
| WO2016177562A1 (en) | 2015-05-01 | 2016-11-10 | Jenavalve Technology, Inc. | Device and method with reduced pacemaker rate in heart valve replacement |
| EP3294351B1 (de) * | 2015-05-11 | 2022-03-23 | Nova Plasma Ltd | Verfahren zur vorbereitung eines silikonimplantats mittels plasmaverarbeitung |
| GB2546319B (en) | 2016-01-15 | 2019-07-03 | Cook Medical Technologies Llc | Coated medical device and method of coating such a device |
| EP4183371A1 (de) | 2016-05-13 | 2023-05-24 | JenaValve Technology, Inc. | Herzklappenprotheseneinführungssystem und verfahren zur einführung einer herzklappenprothese mit einführschleuse und ladesystem |
| JP7094965B2 (ja) | 2017-01-27 | 2022-07-04 | イエナバルブ テクノロジー インク | 心臓弁模倣 |
| GB2564667B (en) * | 2017-07-18 | 2019-12-04 | Cook Medical Technologies Llc | Functionalised coated medical device and method of coating such a device |
| IL272671B2 (en) | 2017-08-16 | 2024-01-01 | Nova Plasma Ltd | Plasma treating an implant |
| GB2568745B (en) | 2017-11-27 | 2022-07-27 | Cook Medical Technologies Llc | Medical device with plasma modified oxide layer and method of forming such a device |
| EP3781222A4 (de) * | 2018-04-20 | 2022-01-26 | Ension, Inc. | Manipulierte bioaktive heparinmatrix für die klinische anwendung einer blutkontaktoberfläche und verfahren zu ihrer herstellung |
| GB2579369B (en) | 2018-11-29 | 2023-08-30 | Cook Medical Technologies Llc | Bioactive agent coated medical device and method of coating such a device |
| EP3659634B1 (de) | 2018-11-29 | 2023-02-22 | Cook Medical Technologies LLC | Mit einem bioaktiven mittel beschichtete medizinische vorrichtung und verfahren zur beschichtung solch einer vorrichtung |
| WO2024102411A1 (en) | 2022-11-09 | 2024-05-16 | Jenavalve Technology, Inc. | Catheter system for sequential deployment of an expandable implant |
| WO2025065051A1 (en) * | 2023-09-25 | 2025-04-03 | The University Of Sydney | Plasma-mediated polymer grafting methodology |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54160474A (en) | 1978-06-09 | 1979-12-19 | Kansai Paint Co Ltd | Modification of surface of high polymer base |
| JPS5980442A (ja) | 1982-09-24 | 1984-05-09 | ベクトン・デイツキンソン・アンド・カンパニ− | 大分子結合用の化学的変成表面 |
| US4508606A (en) | 1983-02-27 | 1985-04-02 | Andrade Joseph D | Process for treating polymer surfaces to reduce their friction resistance characteristics when in contact with non-polar liquid, and resulting products |
| CA1215676A (en) | 1983-04-27 | 1986-12-23 | Terry S. Dunn | Heparinization of plasma treated substrates |
| US5034265A (en) * | 1983-08-01 | 1991-07-23 | Washington Research Foundation | Plasma gas discharge treatment for improving the compatibility of biomaterials |
| US4786556A (en) | 1986-03-24 | 1988-11-22 | Becton, Dickinson And Company | Polymeric articles having enhanced antithrombogenic activity |
| US5169675A (en) | 1987-07-02 | 1992-12-08 | The Standard Oil Company | Bonding of high nitrile resins onto surface plasma treated plastics |
| US5229163A (en) | 1989-12-21 | 1993-07-20 | Hoffmann-La Roche Inc. | Process for preparing a microtiter tray for immunometric determinations |
| US5455040A (en) | 1990-07-26 | 1995-10-03 | Case Western Reserve University | Anticoagulant plasma polymer-modified substrate |
| US5132108A (en) | 1990-11-08 | 1992-07-21 | Cordis Corporation | Radiofrequency plasma treated polymeric surfaces having immobilized anti-thrombogenic agents |
| US5244654A (en) | 1990-11-08 | 1993-09-14 | Cordis Corporation | Radiofrequency plasma biocompatibility treatment of inside surfaces of medical tubing and the like |
| JPH0549689A (ja) | 1991-08-20 | 1993-03-02 | Sony Corp | 細胞接着性材料およびその製造方法 |
| US5336518A (en) | 1992-12-11 | 1994-08-09 | Cordis Corporation | Treatment of metallic surfaces using radiofrequency plasma deposition and chemical attachment of bioactive agents |
| US5229172A (en) * | 1993-01-19 | 1993-07-20 | Medtronic, Inc. | Modification of polymeric surface by graft polymerization |
| JP2803017B2 (ja) | 1993-06-07 | 1998-09-24 | 工業技術院長 | 抗血栓性医用材料及び医療用具並びにこれらの製造方法、製造装置及びプラズマ処理装置 |
| GB9322132D0 (en) * | 1993-10-27 | 1993-12-15 | Zeneca Ltd | Antimicrobial treatment of textile materials |
| US5643580A (en) | 1994-10-17 | 1997-07-01 | Surface Genesis, Inc. | Biocompatible coating, medical device using the same and methods |
| US5607475A (en) | 1995-08-22 | 1997-03-04 | Medtronic, Inc. | Biocompatible medical article and method |
| US5723219A (en) | 1995-12-19 | 1998-03-03 | Talison Research | Plasma deposited film networks |
| AUPN960696A0 (en) * | 1996-05-02 | 1996-05-23 | Commonwealth Scientific And Industrial Research Organisation | Surface modification of polymers |
| US6013855A (en) | 1996-08-06 | 2000-01-11 | United States Surgical | Grafting of biocompatible hydrophilic polymers onto inorganic and metal surfaces |
| WO1998010116A1 (en) | 1996-09-05 | 1998-03-12 | Talison Research | Ultrasonic nozzle feed for plasma deposited film networks |
| US6199787B1 (en) * | 1998-03-02 | 2001-03-13 | Asif Jaffar | Method of transferring individual ends of yarns from a beam to individual cones |
| US6024918A (en) | 1998-03-13 | 2000-02-15 | Medtronic, Inc. | Method for attachment of biomolecules to surfaces of medical devices |
| WO2000048530A1 (en) | 1999-02-16 | 2000-08-24 | Talison Research, Inc. | Multilayer and multifunction vascular graft |
| US6159531A (en) * | 1999-08-30 | 2000-12-12 | Cardiovasc, Inc. | Coating having biological activity and medical implant having surface carrying the same and method |
| EP1088564A1 (de) | 1999-09-30 | 2001-04-04 | Orbus Medical Technologies, Inc. | Intraluminale Vorrichtung, Beschichtung für eine solche Vorrichtung und Verfahren zu deren Herstellung |
-
2001
- 2001-01-31 US US09/772,908 patent/US6632470B2/en not_active Expired - Fee Related
-
2002
- 2002-01-30 AT AT02704264T patent/ATE338571T1/de not_active IP Right Cessation
- 2002-01-30 WO PCT/US2002/002430 patent/WO2002060509A1/en not_active Ceased
- 2002-01-30 EP EP02704264A patent/EP1355686B1/de not_active Expired - Lifetime
- 2002-01-30 DE DE60214513T patent/DE60214513T2/de not_active Expired - Fee Related
- 2002-01-30 JP JP2002560700A patent/JP2004524081A/ja not_active Withdrawn
- 2002-01-30 AU AU2002237956A patent/AU2002237956B2/en not_active Ceased
- 2002-01-30 CA CA002435962A patent/CA2435962A1/en not_active Abandoned
-
2003
- 2003-08-22 US US10/645,704 patent/US20040037946A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002060509A9 (en) | 2004-01-29 |
| JP2004524081A (ja) | 2004-08-12 |
| AU2002237956B2 (en) | 2006-04-13 |
| US20030163198A1 (en) | 2003-08-28 |
| CA2435962A1 (en) | 2002-08-08 |
| DE60214513D1 (de) | 2006-10-19 |
| US20040037946A1 (en) | 2004-02-26 |
| EP1355686A1 (de) | 2003-10-29 |
| WO2002060509A1 (en) | 2002-08-08 |
| EP1355686B1 (de) | 2006-09-06 |
| US6632470B2 (en) | 2003-10-14 |
| DE60214513T2 (de) | 2007-05-10 |
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