ATE336579T1 - Isolierte mhc-klasse ii-bindende peptide, und deren verwendung - Google Patents
Isolierte mhc-klasse ii-bindende peptide, und deren verwendungInfo
- Publication number
- ATE336579T1 ATE336579T1 AT00965439T AT00965439T ATE336579T1 AT E336579 T1 ATE336579 T1 AT E336579T1 AT 00965439 T AT00965439 T AT 00965439T AT 00965439 T AT00965439 T AT 00965439T AT E336579 T1 ATE336579 T1 AT E336579T1
- Authority
- AT
- Austria
- Prior art keywords
- mhc class
- binding peptides
- isolated mhc
- peptides
- molecules
- Prior art date
Links
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 102100025570 Cancer/testis antigen 1 Human genes 0.000 abstract 1
- 102000006354 HLA-DR Antigens Human genes 0.000 abstract 1
- 108010058597 HLA-DR Antigens Proteins 0.000 abstract 1
- 102000018713 Histocompatibility Antigens Class II Human genes 0.000 abstract 1
- 101000856237 Homo sapiens Cancer/testis antigen 1 Proteins 0.000 abstract 1
- 108091054438 MHC class II family Proteins 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/408,036 US6800730B1 (en) | 1998-10-02 | 1999-09-29 | Isolated peptides which bind to MHC class II molecules, and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE336579T1 true ATE336579T1 (de) | 2006-09-15 |
Family
ID=23614589
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00965439T ATE336579T1 (de) | 1999-09-29 | 2000-09-26 | Isolierte mhc-klasse ii-bindende peptide, und deren verwendung |
Country Status (6)
Country | Link |
---|---|
US (2) | US6800730B1 (de) |
EP (1) | EP1220908B1 (de) |
AT (1) | ATE336579T1 (de) |
AU (1) | AU7615900A (de) |
DE (1) | DE60030141T2 (de) |
WO (1) | WO2001023560A2 (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7619057B2 (en) | 2000-01-28 | 2009-11-17 | The United States Of America As Represented By The Secretary, Department Of Health And Human Services | MHC class II restricted T cell epitopes from the cancer antigen, NY ESO-1 |
US8637305B2 (en) * | 2001-11-07 | 2014-01-28 | Mannkind Corporation | Expression vectors encoding epitopes of target-associated antigens and methods for their design |
US20080139464A1 (en) * | 2003-05-30 | 2008-06-12 | Ludwig Institute Of Cancer Research | Isolated Ny-Eso-1 Peptides Which Bind To Hla Class II Molecules And Uses Thereof |
EP1644501B1 (de) | 2003-07-22 | 2011-01-19 | Ludwig Institute For Cancer Research | Von hla-klasse-ii-molekülen präsentierte ssx-2-peptide |
US7632506B2 (en) * | 2004-09-09 | 2009-12-15 | Ludwig Institute For Cancer Research | Identification of new NY-ESO-1 epitopes recognized by CD4+ T-cells |
US20070232558A1 (en) * | 2006-03-31 | 2007-10-04 | Mcneel Douglas G | Methods and compositions for treating prostate cancer using dna vaccines directed to cancer testis antigen |
US7910565B2 (en) | 2006-09-01 | 2011-03-22 | Wisconsin Alumni Research Foundation | Prostate cancer vaccine |
US8309096B2 (en) * | 2007-01-15 | 2012-11-13 | Glaxosmithkline Biologicals S.A. | Fusion protein |
WO2008121836A1 (en) * | 2007-03-30 | 2008-10-09 | Brigham And Women's Hospital, Inc. | Compounds and methods for enhancing mhc class ii therapies |
CN102575284A (zh) | 2009-03-17 | 2012-07-11 | MDx健康公司 | 改进的基因表达检测 |
BR122020026648B1 (pt) | 2010-09-20 | 2021-12-07 | Biontech Cell & Gene Therapies Gmbh | Receptor de células t com especificidade para ny-eso-1, composição farmacêutica compreendendo o mesmo e uso do mesmo |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6723832B1 (en) * | 1996-10-03 | 2004-04-20 | Ludwig Institute For Cancer Research | Isolated peptides corresponding to amino acid sequences of NY-ESO-1, which bind to MHC Class I and MHC Class II molecules, and uses thereof |
US5804381A (en) * | 1996-10-03 | 1998-09-08 | Cornell Research Foundation | Isolated nucleic acid molecule encoding an esophageal cancer associated antigen, the antigen itself, and uses thereof |
DE69334076D1 (de) * | 1992-08-07 | 2006-11-30 | Pharmexa Inc | Hla bindepeptide und ihre verwendungen |
DE69435171D1 (de) * | 1993-09-14 | 2009-01-08 | Pharmexa Inc | Pan dr-bindeproteinen zur erhöhung der immunantwort |
US5824315A (en) * | 1993-10-25 | 1998-10-20 | Anergen, Inc. | Binding affinity of antigenic peptides for MHC molecules |
GB9414580D0 (en) * | 1994-07-19 | 1994-09-07 | Cancer Res Campaign Tech | Materials and methods relating to the diagnosis of synovial sarcomas |
US6251603B1 (en) * | 1996-10-03 | 2001-06-26 | Ludwig Institute For Cancer Research | Method for determining status of a cancerous condition by determining antibodies to NY-ESO-1 in a patient sample |
US6413517B1 (en) * | 1997-01-23 | 2002-07-02 | Epimmune, Inc. | Identification of broadly reactive DR restricted epitopes |
US6287756B1 (en) * | 1997-05-05 | 2001-09-11 | Ludwig Institute For Cancer Research | Methods for determining presence of cancer in a sample by determining expression of an SSX gene |
US5965535A (en) * | 1997-09-12 | 1999-10-12 | Ludwig Institute For Cancer Research | Mage-3 peptides presented by HLA class II molecules |
ES2281935T3 (es) * | 1997-10-08 | 2007-10-01 | The Government Of The Usa, As Represented By The Secretary, Department Of Health And Human Services | Antigeno cancerigeno humano ny eso-1/ca6 y gen que codifica para el mismo. |
JP2002506633A (ja) * | 1998-03-20 | 2002-03-05 | ジェンザイム・コーポレーション | T細胞応答を誘発するための遺伝子に基づくワクチンの組成物および使用法 |
-
1999
- 1999-09-29 US US09/408,036 patent/US6800730B1/en not_active Expired - Lifetime
-
2000
- 2000-09-26 WO PCT/US2000/026411 patent/WO2001023560A2/en active IP Right Grant
- 2000-09-26 EP EP00965439A patent/EP1220908B1/de not_active Expired - Lifetime
- 2000-09-26 AT AT00965439T patent/ATE336579T1/de active
- 2000-09-26 DE DE60030141T patent/DE60030141T2/de not_active Expired - Lifetime
- 2000-09-26 AU AU76159/00A patent/AU7615900A/en not_active Abandoned
-
2004
- 2004-05-21 US US10/851,884 patent/US7385044B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1220908A2 (de) | 2002-07-10 |
WO2001023560A2 (en) | 2001-04-05 |
US20040214284A1 (en) | 2004-10-28 |
US6800730B1 (en) | 2004-10-05 |
US7385044B2 (en) | 2008-06-10 |
DE60030141T2 (de) | 2007-08-09 |
WO2001023560A3 (en) | 2001-11-29 |
AU7615900A (en) | 2001-04-30 |
EP1220908B1 (de) | 2006-08-16 |
DE60030141D1 (de) | 2006-09-28 |
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Legal Events
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UEP | Publication of translation of european patent specification |
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