ATE336572T1 - Neuen reagenzien in chemilumineszenz- nachweisverfahren - Google Patents

Neuen reagenzien in chemilumineszenz- nachweisverfahren

Info

Publication number
ATE336572T1
ATE336572T1 AT02735389T AT02735389T ATE336572T1 AT E336572 T1 ATE336572 T1 AT E336572T1 AT 02735389 T AT02735389 T AT 02735389T AT 02735389 T AT02735389 T AT 02735389T AT E336572 T1 ATE336572 T1 AT E336572T1
Authority
AT
Austria
Prior art keywords
chemiluminescence detection
detection methods
compounds
precursor
leaving group
Prior art date
Application number
AT02735389T
Other languages
German (de)
English (en)
Inventor
Dieter Heindl
Rupert Herrmann
Hans-Peter Josel
Erasmus Huber
Ursula Klause
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE336572T1 publication Critical patent/ATE336572T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/06—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/80—Fluorescent dyes, e.g. rhodamine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/904—Oxidation - reduction indicators
AT02735389T 2001-06-01 2002-05-28 Neuen reagenzien in chemilumineszenz- nachweisverfahren ATE336572T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP01112879 2001-06-01

Publications (1)

Publication Number Publication Date
ATE336572T1 true ATE336572T1 (de) 2006-09-15

Family

ID=8177561

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02735389T ATE336572T1 (de) 2001-06-01 2002-05-28 Neuen reagenzien in chemilumineszenz- nachweisverfahren

Country Status (9)

Country Link
US (1) US7332354B2 (pt-PT)
EP (1) EP1397488B1 (pt-PT)
JP (1) JP2004535423A (pt-PT)
AT (1) ATE336572T1 (pt-PT)
AU (1) AU2002310743A1 (pt-PT)
CA (1) CA2448824A1 (pt-PT)
DE (1) DE60213986T2 (pt-PT)
ES (1) ES2271263T3 (pt-PT)
WO (1) WO2002099097A1 (pt-PT)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10022078B2 (en) 2004-07-13 2018-07-17 Dexcom, Inc. Analyte sensor
DE10303265A1 (de) * 2003-01-28 2004-07-29 Roche Diagnostics Gmbh Fluorimetrische Bestimmung von Analyten durch ein intramolekulares Quencher-Fluorophor-Konjugat
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
US7654956B2 (en) 2004-07-13 2010-02-02 Dexcom, Inc. Transcutaneous analyte sensor
US20090053747A1 (en) * 2007-08-21 2009-02-26 Mattingly Phillip G Measurement of Haloperoxidase Activity With Chemiluminescent Detection
US20090148871A1 (en) * 2007-12-10 2009-06-11 Mattingly Phillip G Interdependent Assays for Detecting Two or More Analytes of Interest in A Test Sample
CN102378750A (zh) * 2009-03-31 2012-03-14 东丽株式会社 发光元件材料前体和其制造方法
PL2989446T3 (pl) * 2013-04-24 2019-02-28 Euroimmun Medizinische Labordiagnostika Ag Sposób zautomatyzowanej oceny inkubowanych pasków testowych immunoblot

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3537877A1 (de) * 1985-10-24 1987-04-30 Geiger Reinhard Luciferin-derivate und immunoassays unter einsatz derartiger luciferin-derivate
ES2063735T3 (es) * 1986-10-22 1995-01-16 Abbott Lab Sales de acridinio quimioluminiscentes.
EP0511366A1 (en) * 1990-11-21 1992-11-04 Beckman Instruments, Inc. Chemiluminescent compounds
US5344928A (en) 1991-04-26 1994-09-06 Takeda Chemical Industries, Ltd. Phenothiazine derivatives, their production and use
US5593845A (en) * 1993-05-17 1997-01-14 Lumigen, Inc. Aryl N-alkylacridancarboxylate derivatives useful for chemiluminescent detection
US5491072A (en) 1993-05-17 1996-02-13 Lumigen, Inc. N-alkylacridan carboxyl derivatives useful for chemiluminescent detection
BE1008216A4 (fr) * 1994-01-25 1996-02-20 Biocode Sa Derives chemoluminescents heterocycliques.
US5589328A (en) * 1994-08-04 1996-12-31 Mahant; Vijay K. Chemiluminescence assays based on indoxyl substrates, thioindoxyl substrates and other substrates
KR100259761B1 (ko) 1996-03-15 2000-07-01 타이도 나오카타 에스에이치기 표지용시약, 그의 제조방법 및 이를 이용한 표지법
BE1011206A4 (fr) 1997-06-11 1999-06-01 Biocode Sa Derives chimioluminescents heterocycliques.
EP1203091B1 (en) * 1999-07-30 2005-03-16 Bayer Corporation Chemiluminescent substrates of hydrolytic enzymes such as phosphatases

Also Published As

Publication number Publication date
JP2004535423A (ja) 2004-11-25
DE60213986T2 (de) 2007-09-06
AU2002310743A1 (en) 2002-12-16
US7332354B2 (en) 2008-02-19
WO2002099097A8 (en) 2003-03-06
ES2271263T3 (es) 2007-04-16
EP1397488A1 (en) 2004-03-17
DE60213986D1 (de) 2006-09-28
EP1397488B1 (en) 2006-08-16
CA2448824A1 (en) 2002-12-12
WO2002099097A1 (en) 2002-12-12
US20040214999A1 (en) 2004-10-28

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