ATE334994T1 - Lösungsmittelsystem zur herstellung von bisphosphonat - Google Patents
Lösungsmittelsystem zur herstellung von bisphosphonatInfo
- Publication number
- ATE334994T1 ATE334994T1 AT02253548T AT02253548T ATE334994T1 AT E334994 T1 ATE334994 T1 AT E334994T1 AT 02253548 T AT02253548 T AT 02253548T AT 02253548 T AT02253548 T AT 02253548T AT E334994 T1 ATE334994 T1 AT E334994T1
- Authority
- AT
- Austria
- Prior art keywords
- bisphosphonate
- producing
- solvent system
- solvent
- bisphosphonates
- Prior art date
Links
- 229940122361 Bisphosphonate Drugs 0.000 title abstract 2
- 150000004663 bisphosphonates Chemical class 0.000 title abstract 2
- 239000002904 solvent Substances 0.000 title abstract 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 abstract 2
- -1 phosphorus halide Chemical class 0.000 abstract 2
- 229910000147 aluminium phosphate Inorganic materials 0.000 abstract 1
- 150000001728 carbonyl compounds Chemical class 0.000 abstract 1
- 229910052698 phosphorus Inorganic materials 0.000 abstract 1
- 239000011574 phosphorus Substances 0.000 abstract 1
- ISIJQEHRDSCQIU-UHFFFAOYSA-N tert-butyl 2,7-diazaspiro[4.5]decane-7-carboxylate Chemical compound C1N(C(=O)OC(C)(C)C)CCCC11CNCC1 ISIJQEHRDSCQIU-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/5532—Seven-(or more) membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3839—Polyphosphonic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3839—Polyphosphonic acids
- C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Cyclones (AREA)
- Photographic Developing Apparatuses (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0115824.5A GB0115824D0 (en) | 2001-06-28 | 2001-06-28 | Improved solvent systems |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE334994T1 true ATE334994T1 (de) | 2006-08-15 |
Family
ID=9917538
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02253548T ATE334994T1 (de) | 2001-06-28 | 2002-05-21 | Lösungsmittelsystem zur herstellung von bisphosphonat |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US6878846B2 (de) |
| EP (1) | EP1364956B8 (de) |
| AT (1) | ATE334994T1 (de) |
| CA (1) | CA2391785C (de) |
| DE (1) | DE60213566T2 (de) |
| GB (2) | GB0115824D0 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20020908A1 (it) * | 2002-04-29 | 2003-10-29 | Chemi Spa | Processo di preparazione di sodio alendronato |
| KR100681282B1 (ko) * | 2002-05-17 | 2007-02-12 | 테바 파마슈티컬 인더스트리즈 리미티드 | 특정 희석제를 사용하는 비스포스폰산 및 그 염의 제조방법 |
| ATE451380T1 (de) * | 2003-08-21 | 2009-12-15 | Sun Pharmaceuticals Ind Ltd | Verfahren zur herstellung von bisphosphonsäureverbindungen |
| US8003820B2 (en) * | 2005-10-20 | 2011-08-23 | Dr. Reddy's Laboratories Limited | Process for preparing bisphosphonic acids |
| EP2016084A2 (de) * | 2006-05-11 | 2009-01-21 | Ind-Swift Laboratories Limited | Verfahren zur herstellung von reiner risedronsäure oder -salzen |
| WO2008157050A1 (en) * | 2007-06-19 | 2008-12-24 | Albemarle Corporation | Processes for manufacturing bisphosphonic acids |
| EP2470549B1 (de) * | 2009-08-28 | 2014-07-16 | Synthon B.V. | Verfahren zur herstellung von hydroxyalkyliden-1,1-biphosphonsäuren |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4835948B1 (de) | 1968-11-04 | 1973-10-31 | ||
| JPS5234746B2 (de) * | 1972-12-27 | 1977-09-05 | ||
| DE3016289A1 (de) * | 1980-04-28 | 1981-10-29 | Henkel KGaA, 4000 Düsseldorf | Verfahren zur herstellung von omega -amino-1-hydroxyalkyliden-1,1-bis-phosphonsaeuren |
| DD152352A1 (de) * | 1980-08-01 | 1981-11-25 | Karlheinz Koch | Verfahren zur herstellung strahlenchemisch haertbarer reaktionsharzmassen |
| DE3700772A1 (de) * | 1987-01-13 | 1988-07-21 | Inst Khim Kinetiki I Gorenija | Verfahren zur herstellung von i-funktionellsubstituierten alkyliden-i,i-diphosphonsaeuren und deren gemischen |
| US5019651A (en) * | 1990-06-20 | 1991-05-28 | Merck & Co., Inc. | Process for preparing 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid (ABP) or salts thereof |
| GB9325113D0 (en) * | 1993-12-08 | 1994-02-09 | Albright & Wilson | Substituted phosphonic acids |
| FR2749775B1 (fr) * | 1996-06-13 | 1998-07-24 | Ceca Sa | Procede de traitement d'engrais par compositions hydrophobantes/antimottantes en vue de leur stockage en vrac |
| CA2197267C (en) * | 1997-02-11 | 2000-02-08 | Yong Tao | Process for the production of 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid or salts thereof |
| RU2179152C2 (ru) * | 2000-01-31 | 2002-02-10 | Институт органической и физической химии им. А.Е. Арбузова Казанского научного центра РАН | Способ получения фосфористой кислоты (варианты) |
| PE20011065A1 (es) * | 2000-02-01 | 2001-11-21 | Procter & Gamble | Proceso para fabricar bisfosfonatos geminales |
-
2001
- 2001-06-28 GB GBGB0115824.5A patent/GB0115824D0/en not_active Ceased
-
2002
- 2002-05-21 DE DE60213566T patent/DE60213566T2/de not_active Expired - Lifetime
- 2002-05-21 EP EP02253548A patent/EP1364956B8/de not_active Expired - Lifetime
- 2002-05-21 GB GB0211589A patent/GB2378444B/en not_active Expired - Fee Related
- 2002-05-21 AT AT02253548T patent/ATE334994T1/de not_active IP Right Cessation
- 2002-06-21 US US10/177,130 patent/US6878846B2/en not_active Expired - Lifetime
- 2002-06-27 CA CA002391785A patent/CA2391785C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1364956B1 (de) | 2006-08-02 |
| CA2391785A1 (en) | 2002-12-28 |
| DE60213566T2 (de) | 2007-10-04 |
| US20030013918A1 (en) | 2003-01-16 |
| GB2378444A (en) | 2003-02-12 |
| EP1364956B8 (de) | 2006-12-20 |
| GB0115824D0 (en) | 2001-08-22 |
| GB0211589D0 (en) | 2002-06-26 |
| US6878846B2 (en) | 2005-04-12 |
| GB2378444B (en) | 2005-06-15 |
| DE60213566D1 (de) | 2006-09-14 |
| EP1364956A1 (de) | 2003-11-26 |
| CA2391785C (en) | 2008-11-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |