ATE323776T1 - Retrovirale vektoren zur expression in embryonalen zellen - Google Patents

Retrovirale vektoren zur expression in embryonalen zellen

Info

Publication number
ATE323776T1
ATE323776T1 AT95944182T AT95944182T ATE323776T1 AT E323776 T1 ATE323776 T1 AT E323776T1 AT 95944182 T AT95944182 T AT 95944182T AT 95944182 T AT95944182 T AT 95944182T AT E323776 T1 ATE323776 T1 AT E323776T1
Authority
AT
Austria
Prior art keywords
vector
retroviral
expression
virus
retroviral vectors
Prior art date
Application number
AT95944182T
Other languages
English (en)
Inventor
Donald B Kohn
Pia M Challita
Original Assignee
Children S Hospital Los Angele
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Children S Hospital Los Angele filed Critical Children S Hospital Los Angele
Application granted granted Critical
Publication of ATE323776T1 publication Critical patent/ATE323776T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/11011Alpharetrovirus, e.g. avian leucosis virus
    • C12N2740/11022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/13011Gammaretrovirus, e.g. murine leukeamia virus
    • C12N2740/13041Use of virus, viral particle or viral elements as a vector
    • C12N2740/13043Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
AT95944182T 1994-12-21 1995-12-19 Retrovirale vektoren zur expression in embryonalen zellen ATE323776T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/361,112 US5707865A (en) 1994-12-21 1994-12-21 Retroviral vectors for expression in embryonic cells

Publications (1)

Publication Number Publication Date
ATE323776T1 true ATE323776T1 (de) 2006-05-15

Family

ID=23420695

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95944182T ATE323776T1 (de) 1994-12-21 1995-12-19 Retrovirale vektoren zur expression in embryonalen zellen

Country Status (11)

Country Link
US (1) US5707865A (de)
EP (1) EP0801575B1 (de)
JP (1) JPH10510995A (de)
AT (1) ATE323776T1 (de)
AU (1) AU693317B2 (de)
CA (1) CA2208210A1 (de)
DE (1) DE69534948T2 (de)
DK (1) DK0801575T3 (de)
NZ (1) NZ300795A (de)
PT (1) PT801575E (de)
WO (1) WO1996019245A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0835320A1 (de) * 1995-05-10 1998-04-15 Introgene B.V. Verbesserte retroviralen vektoren, besonders angepasst zur gen-therapie
WO1996038545A1 (fr) * 1995-06-02 1996-12-05 Wakunaga Seiyaku Kabushiki Kaisha Cellules generatrices de retrovirus de recombinaison
US7129043B1 (en) * 1998-10-22 2006-10-31 Duke University Methods of screening for risk of proliferative disease and methods for the treatment of proliferative disease
US6642038B1 (en) * 1999-09-14 2003-11-04 Genzyme Glycobiology Research Institute, Inc. GlcNAc phosphotransferase of the lysosomal targeting pathway
US6770468B1 (en) 1999-09-14 2004-08-03 Genzyme Glycobiology Research Institute, Inc. Phosphodiester-α-GlcNAcase of the lysosomal targeting pathway
ATE403676T1 (de) 2001-05-31 2008-08-15 Novartis Ag Neue östrogenrezeptorligandenbindungsdomänen varianten und neue liganden und pharmazeutische zusammensetzungen
US6905856B2 (en) * 2001-12-21 2005-06-14 Genzyme Glycobiology Research Institute, Inc. Soluble GlcNAc phosphotransferase
US6800472B2 (en) * 2001-12-21 2004-10-05 Genzyme Glycobiology Research Institute, Inc. Expression of lysosomal hydrolase in cells expressing pro-N-acetylglucosamine-1-phosphodiester α-N-acetyl glucosimanidase
US20030124652A1 (en) * 2001-12-21 2003-07-03 Novazyme Pharmaceuticals, Inc. Methods of producing high mannose glycoproteins in complex carbohydrate deficient cells
US20040009158A1 (en) * 2002-07-11 2004-01-15 Washington University Promotion of neovascularization using bone marrow-derived endothelial-progenitor cells
AU2015296861A1 (en) 2014-07-31 2017-02-16 The Board Of Regents Of The University Of Oklahoma High isomerohydrolase activity mutants of mammalian RPE65
CN110607394A (zh) * 2018-06-15 2019-12-24 云舟生物科技(广州)有限公司 莫洛尼鼠白血病病毒滴度检测试剂盒及滴度检测方法

Also Published As

Publication number Publication date
AU693317B2 (en) 1998-06-25
EP0801575B1 (de) 2006-04-19
PT801575E (pt) 2006-08-31
DE69534948D1 (de) 2006-05-24
JPH10510995A (ja) 1998-10-27
DK0801575T3 (da) 2006-08-21
EP0801575A1 (de) 1997-10-22
US5707865A (en) 1998-01-13
AU4604696A (en) 1996-07-10
CA2208210A1 (en) 1996-06-27
WO1996019245A1 (en) 1996-06-27
NZ300795A (en) 2001-08-31
DE69534948T2 (de) 2006-11-16
EP0801575A4 (de) 2001-08-16

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