ATE321561T1 - Azidoderivate von beta-l-2'-nukleosiden zur hiv- infektionsbehandlung - Google Patents

Azidoderivate von beta-l-2'-nukleosiden zur hiv- infektionsbehandlung

Info

Publication number
ATE321561T1
ATE321561T1 AT99971324T AT99971324T ATE321561T1 AT E321561 T1 ATE321561 T1 AT E321561T1 AT 99971324 T AT99971324 T AT 99971324T AT 99971324 T AT99971324 T AT 99971324T AT E321561 T1 ATE321561 T1 AT E321561T1
Authority
AT
Austria
Prior art keywords
beta
acido
nucleosides
derivatives
hiv infection
Prior art date
Application number
AT99971324T
Other languages
English (en)
Inventor
Gilles Gosselin
Jean-Louis Imbach
Jean-Pierre Sommadossi
Raymond F Schinazi
Original Assignee
Centre Nat Rech Scient
Uab Research Foundation
Univ Emory
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Nat Rech Scient, Uab Research Foundation, Univ Emory filed Critical Centre Nat Rech Scient
Application granted granted Critical
Publication of ATE321561T1 publication Critical patent/ATE321561T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AT99971324T 1998-11-05 1999-11-05 Azidoderivate von beta-l-2'-nukleosiden zur hiv- infektionsbehandlung ATE321561T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10717898P 1998-11-05 1998-11-05
US11586299P 1999-01-13 1999-01-13

Publications (1)

Publication Number Publication Date
ATE321561T1 true ATE321561T1 (de) 2006-04-15

Family

ID=26804484

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99971324T ATE321561T1 (de) 1998-11-05 1999-11-05 Azidoderivate von beta-l-2'-nukleosiden zur hiv- infektionsbehandlung

Country Status (12)

Country Link
EP (1) EP1124565B1 (de)
JP (2) JP2002528510A (de)
KR (1) KR100679239B1 (de)
AT (1) ATE321561T1 (de)
AU (1) AU768059B2 (de)
BR (1) BR9915037A (de)
CA (1) CA2348948C (de)
DE (1) DE69930678T2 (de)
ES (1) ES2262366T3 (de)
IL (2) IL142982A0 (de)
MX (1) MXPA01004505A (de)
WO (1) WO2000025799A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY164523A (en) 2000-05-23 2017-12-29 Univ Degli Studi Cagliari Methods and compositions for treating hepatitis c virus
CA2410579C (en) 2000-05-26 2010-04-20 Jean-Pierre Sommadossi Methods and compositions for treating flaviviruses and pestiviruses
CN1849142A (zh) 2002-11-15 2006-10-18 埃迪尼克斯(开曼)有限公司 2′－支链核苷和黄病毒突变

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD293498A5 (de) * 1989-07-20 1991-09-05 Zi Fuer Molekularbiologie Der Adw,De Verfahren zur herstellung eines mittels fuer die behandlung oder prophylaxe von hepatits-infektionen bei mensch und tier
WO1995007086A1 (en) * 1993-09-10 1995-03-16 Emory University Nucleosides with anti-hepatitis b virus activity
DE69638137D1 (de) * 1995-09-07 2010-04-15 Univ Georgia Therapeutische azidverbindungen
JP2002503212A (ja) * 1996-10-16 2002-01-29 アイ・シー・エヌ・フアーマシユーテイカルズ・インコーポレイテツド 単環式ヌクレオシド、その類似体および使用

Also Published As

Publication number Publication date
AU1469100A (en) 2000-05-22
JP2002528510A (ja) 2002-09-03
IL142982A (en) 2010-05-17
IL142982A0 (en) 2002-04-21
CA2348948C (en) 2007-09-18
KR20020013475A (ko) 2002-02-20
BR9915037A (pt) 2001-11-20
DE69930678D1 (de) 2006-05-18
JP2011251968A (ja) 2011-12-15
EP1124565B1 (de) 2006-03-29
EP1124565A1 (de) 2001-08-22
AU768059B2 (en) 2003-12-04
CA2348948A1 (en) 2000-05-11
MXPA01004505A (es) 2005-04-19
WO2000025799A1 (en) 2000-05-11
ES2262366T3 (es) 2006-11-16
DE69930678T2 (de) 2006-09-21
KR100679239B1 (ko) 2007-02-07

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