ATE308996T1 - Gelträgerstoffe für antiproliferierende mittel - Google Patents

Gelträgerstoffe für antiproliferierende mittel

Info

Publication number
ATE308996T1
ATE308996T1 AT98908583T AT98908583T ATE308996T1 AT E308996 T1 ATE308996 T1 AT E308996T1 AT 98908583 T AT98908583 T AT 98908583T AT 98908583 T AT98908583 T AT 98908583T AT E308996 T1 ATE308996 T1 AT E308996T1
Authority
AT
Austria
Prior art keywords
agents
antiproliferant
gel carrier
antiproliferative
methods
Prior art date
Application number
AT98908583T
Other languages
English (en)
Inventor
Richard E Jones
Keith Washco
George Trager
Kathleen V Roskos
Richard Maskiewicz
Original Assignee
Intarcia Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intarcia Therapeutics Inc filed Critical Intarcia Therapeutics Inc
Application granted granted Critical
Publication of ATE308996T1 publication Critical patent/ATE308996T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
AT98908583T 1997-02-20 1998-02-19 Gelträgerstoffe für antiproliferierende mittel ATE308996T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/803,128 US6630168B1 (en) 1997-02-20 1997-02-20 Gel delivery vehicles for anticellular proliferative agents
PCT/US1998/003107 WO1998036776A2 (en) 1997-02-20 1998-02-19 Gel delivery vehicles for anticellular proliferative agents

Publications (1)

Publication Number Publication Date
ATE308996T1 true ATE308996T1 (de) 2005-11-15

Family

ID=25185657

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98908583T ATE308996T1 (de) 1997-02-20 1998-02-19 Gelträgerstoffe für antiproliferierende mittel

Country Status (13)

Country Link
US (4) US6630168B1 (de)
EP (1) EP0971745B1 (de)
JP (1) JP2001512487A (de)
KR (1) KR100611137B1 (de)
CN (1) CN1212154C (de)
AT (1) ATE308996T1 (de)
AU (1) AU746938B2 (de)
CA (1) CA2281919A1 (de)
DE (1) DE69832266T2 (de)
HK (1) HK1026142A1 (de)
NO (1) NO994015L (de)
NZ (1) NZ337875A (de)
WO (1) WO1998036776A2 (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6630168B1 (en) * 1997-02-20 2003-10-07 Biomedicines, Inc. Gel delivery vehicles for anticellular proliferative agents
US6040330A (en) * 1999-01-08 2000-03-21 Bionumerik Pharmaceuticals, Inc. Pharmaceutical formulations of taxanes
EP1387676A2 (de) * 2001-05-01 2004-02-11 Angiotech Pharmaceuticals, Inc. Zusammensetzung enthaltend eine substanz mit anti-mikrotubulärer wirkung und ein polysaccharid oder polypeptid und ihre verwendung zur herstellung eines medikaments zur behandlung von entzündlichen erkrankungen
CA2456746A1 (en) * 2001-08-20 2003-02-27 Transave, Inc. Method for treating lung cancers
WO2003034988A2 (en) * 2001-10-19 2003-05-01 Idexx Laboratories, Inc. Injectable compositions for the controlled delivery of pharmacologically active compound
US6946137B2 (en) * 2001-10-19 2005-09-20 Idexx Laboratories, Inc. Methods for the controlled delivery of pharmacologically active compounds
AU2003302314A1 (en) * 2002-08-02 2004-07-09 Transave, Inc. Platinum aggregates and process for producing the same
US9186322B2 (en) * 2002-08-02 2015-11-17 Insmed Incorporated Platinum aggregates and process for producing the same
US7670627B2 (en) * 2002-12-09 2010-03-02 Salvona Ip Llc pH triggered targeted controlled release systems for the delivery of pharmaceutical active ingredients
CN100548228C (zh) * 2003-11-13 2009-10-14 阿尔扎公司 用于透皮递送的组合物和装置
US20040224019A1 (en) * 2004-03-03 2004-11-11 Adi Shefer Oral controlled release system for targeted drug delivery into the cell and its nucleus for gene therapy, DNA vaccination, and administration of gene based drugs
CN1976711A (zh) * 2004-03-18 2007-06-06 特兰萨维股份有限公司 通过吸入给药顺铂
US20070065522A1 (en) * 2004-03-18 2007-03-22 Transave, Inc. Administration of high potency platinum compound formulations by inhalation
CA2566174A1 (en) * 2004-05-21 2005-12-01 Transave, Inc. Treatment of lung diseases and pre-lung disease conditions
US7858115B2 (en) 2004-06-24 2010-12-28 Idexx Laboratories Phospholipid gel compositions for drug delivery and methods of treating conditions using same
JP5324091B2 (ja) * 2004-06-24 2013-10-23 アイデックス ラボラトリーズ，インコーポレイティド 薬物送達のための医薬組成物及びそれを使用する症状の治療又は予防法
US7854943B2 (en) 2004-06-24 2010-12-21 Idexx Laboratories Phospholipid gel compositions for drug delivery and methods of treating conditions using same
US7618651B2 (en) 2004-06-24 2009-11-17 Idexx Laboratories Pharmaceutical compositions for drug delivery and methods of treating or preventing conditions using same
MX2007004955A (es) * 2004-11-08 2007-06-14 Transave Inc Metodo de tratar cancer con formulaciones de compeusto de platino a base de lipido administradas intraperitonealmente.
US20060141040A1 (en) * 2004-12-23 2006-06-29 Guohua Chen Injectable non-aqueous suspension
WO2007056264A2 (en) * 2005-11-08 2007-05-18 Transave, Inc. Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally
US20070190180A1 (en) * 2005-11-08 2007-08-16 Pilkiewicz Frank G Methods of treating cancer with high potency lipid-based platinum compound formulations administered intravenously
US9107824B2 (en) 2005-11-08 2015-08-18 Insmed Incorporated Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally
WO2007056236A2 (en) * 2005-11-08 2007-05-18 Transave, Inc. Methods of treating cancer with lipid-based platinum compound formulations administered intravenously
WO2007064658A2 (en) * 2005-11-30 2007-06-07 Transave, Inc. Safe and effective methods of administering therapeutic agents
US20070248630A1 (en) * 2006-04-20 2007-10-25 Friden Phillip M Pharmaceutical formulations for iontophoretic methotrexate delivery
JP2015530387A (ja) 2012-09-04 2015-10-15 エライゾン ファーマシューティカルズ， エルエルシー 脂質複合体化シスプラチンによる肺癌の再発防止
CA2931547A1 (en) 2013-12-09 2015-06-18 Durect Corporation Pharmaceutically active agent complexes, polymer complexes, and compositions and methods involving the same
US20160346221A1 (en) 2015-06-01 2016-12-01 Autotelic Llc Phospholipid-coated therapeutic agent nanoparticles and related methods
MY194732A (en) * 2015-09-18 2022-12-15 Huntsman Petrochemical Llc Improved poly(vinyl caprolactam) kinetic gas hydrate inhibitor and method for preparing the same
WO2020081148A1 (en) * 2018-10-16 2020-04-23 US Nano Food & Drug INC Intratumor injection formulation
IN202121042020A (de) * 2021-09-17 2023-03-24

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3888995A (en) * 1968-07-19 1975-06-10 Syntex Corp Fatty alcohol-propylene glycol vehicle
CA1248450A (en) * 1984-04-05 1989-01-10 Kazuo Kigasawa Soft patch
US4619913A (en) 1984-05-29 1986-10-28 Matrix Pharmaceuticals, Inc. Treatments employing drug-containing matrices for introduction into cellular lesion areas
JPS6219528A (ja) 1985-07-16 1987-01-28 Kurorera Kogyo Kk 制癌剤
DE3603444A1 (de) * 1986-02-05 1987-08-06 Thomae Gmbh Dr K Pharmazeutische zubereitungsformen zur stabilisierung von interferon alpha
JPH0730029B2 (ja) * 1986-09-08 1995-04-05 株式会社クラレ １−置換アザシクロヘプタン−２−オン及びこれを含有する経皮投与用薬剤
DE3631413A1 (de) 1986-09-16 1988-03-24 Knoll Ag Therapeutisches system zur lokalen applikation von pharmawirkstoffen
US5719197A (en) 1988-03-04 1998-02-17 Noven Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
US4938763B1 (en) 1988-10-03 1995-07-04 Atrix Lab Inc Biodegradable in-situ forming implants and method of producing the same
US5051257A (en) 1989-05-09 1991-09-24 Pietronigro Dennis D Antineoplastic solution and method for treating neoplasms
US5487897A (en) * 1989-07-24 1996-01-30 Atrix Laboratories, Inc. Biodegradable implant precursor
SE8904296D0 (sv) * 1989-12-21 1989-12-21 Pharmacia Ab Transdermal system
CA2061566C (en) 1992-02-20 2002-07-09 Rudolf E. Falk Treatment of disease employing hyaluronic acid and nsaids
GB9310049D0 (en) 1993-05-12 1993-06-30 Cancer Res Campaign Tech Growth factor effects
CA2180260A1 (en) * 1993-12-29 1995-07-06 Dennis M. Brown Methods and compositions for the treatment of a host with a cellular proliferative disease
DK0754032T3 (da) * 1994-04-08 2002-04-02 Atrix Lab Inc Flydende frigivelsessammensætninger
US5603955A (en) * 1994-07-18 1997-02-18 University Of Cincinnati Enhanced loading of solutes into polymer gels
US5567420A (en) * 1994-11-16 1996-10-22 Mceleney; John Lotion which is temporarily colored upon application
US5736152A (en) * 1995-10-27 1998-04-07 Atrix Laboratories, Inc. Non-polymeric sustained release delivery system
EP1039885A1 (de) 1996-12-17 2000-10-04 Lidak Pharmaceuticals Verwendung von c18 bis c26-aliphatischen alkoholen zur herstellung eines medikaments für die behandlung von hyperproliferativen hauterkrankungen
US5993856A (en) 1997-01-24 1999-11-30 Femmepharma Pharmaceutical preparations and methods for their administration
US6630168B1 (en) * 1997-02-20 2003-10-07 Biomedicines, Inc. Gel delivery vehicles for anticellular proliferative agents

Also Published As

Publication number Publication date
KR100611137B1 (ko) 2006-08-10
NZ337875A (en) 2001-09-28
AU6658398A (en) 1998-09-09
CN1212154C (zh) 2005-07-27
WO1998036776A2 (en) 1998-08-27
WO1998036776A3 (en) 1998-11-26
DE69832266T2 (de) 2006-08-03
EP0971745A2 (de) 2000-01-19
DE69832266D1 (de) 2005-12-15
AU746938B2 (en) 2002-05-09
KR20000075543A (ko) 2000-12-15
CN1251045A (zh) 2000-04-19
EP0971745B1 (de) 2005-11-09
NO994015D0 (no) 1999-08-19
US6630168B1 (en) 2003-10-07
CA2281919A1 (en) 1998-08-27
US20040131646A1 (en) 2004-07-08
US20040076679A1 (en) 2004-04-22
HK1026142A1 (en) 2000-12-08
NO994015L (no) 1999-10-15
US6669958B1 (en) 2003-12-30
JP2001512487A (ja) 2001-08-21

Similar Documents

Publication Publication Date Title
ATE308996T1 (de) Gelträgerstoffe für antiproliferierende mittel
DE69840660D1 (de) Mobiles Kommunikationssystem und mobiles Kommunikationsverfahren dafür
BRPI0417254A (pt) métodos e equipamentos para roaming cdma2000/gprs
ATE202132T1 (de) Vernetzte biokompatible verkapselungszusammensetzungen und verfahren
IT1296459B1 (it) Attrezzatura interna per veicolo, quale, ad esempio, autoveicolo.
ATE362270T1 (de) Verfahren und mechanismus zum übertragen von nachrichten
IL132115A0 (en) Drug preparations for treating sexual dysfunction
DE69938073D1 (de) Kraftfahrzeug-Kommunikationsverfahren, und System dafür
DE60035907D1 (de) Mobiles Kommunkationsgerät, Kommunikationssystem und Kommunikationsverfahren
FI956185A (fi) Matkaviestinlaite, erityisesti junaviestintään
DE69717999D1 (de) Bis-platin komplexe mit polyamin-liganden als antitumorales mittel
IT1282731B1 (it) Morsetto di batteria per autoveicolo.
EE200000367A (et) Mobiilraadioside meetod, seade ja terminal
FI964416A0 (fi) Tiedonsiirtomenetelmä, solukkojärjestelmä ja matkaTiedonsiirtomenetelmä, solukkojärjestelmä ja matkaviestin viestin
IT8919717A0 (it) Equipaggiamento elettrico di trazione, in particolare per veicoli da trasporto pubblico.
DE69827832D1 (de) Mobile kommunikationsanordnung und mobiles kommunikationsverfahren
ITRM980002A0 (it) Metodo ed apparato per l'immagazzinamento di apparecchiature, macchinari e mezzi mobili, in atmosfera controllata.
DE60025518D1 (de) Hypoglykämische mittel, die organische zinkkomplexe enthalten
DE50016077D1 (de) Antriebssystem für Fahrzeuge, insbesondere für Nutzkraftwagen und elektrische Baueinheit
WO2000058506A3 (en) Susceptibility to psoriasis
ES1036631Y (es) Dispositivo perfeccionado, adaptable y portador para telefonos moviles.
MX9702042A (es) Piridinas sustituidas por 2-arilo.
WO1999024052A3 (en) Use of protein h as cytostatic agent
BR9701024B1 (pt) processo e aparelho para localização de telefone e estação móvel.
IT1285063B1 (it) Dispositivo antinebulizzazione per veicoli, in particolare veicoli industriali.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties