ATE300612T1 - Theta-untereinheit des menschlichen gaba-a rezeptors - Google Patents
Theta-untereinheit des menschlichen gaba-a rezeptorsInfo
- Publication number
- ATE300612T1 ATE300612T1 AT98917470T AT98917470T ATE300612T1 AT E300612 T1 ATE300612 T1 AT E300612T1 AT 98917470 T AT98917470 T AT 98917470T AT 98917470 T AT98917470 T AT 98917470T AT E300612 T1 ATE300612 T1 AT E300612T1
- Authority
- AT
- Austria
- Prior art keywords
- receptor
- human gaba
- theta subunit
- cell line
- subunit
- Prior art date
Links
- 102000004300 GABA-A Receptors Human genes 0.000 title 1
- 108090000839 GABA-A Receptors Proteins 0.000 title 1
- 239000002299 complementary DNA Substances 0.000 abstract 2
- 102000027484 GABAA receptors Human genes 0.000 abstract 1
- 108091008681 GABAA receptors Proteins 0.000 abstract 1
- 238000010367 cloning Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Electrotherapy Devices (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Radio Relay Systems (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9708479.2A GB9708479D0 (en) | 1997-04-25 | 1997-04-25 | Nucleic acids |
| PCT/GB1998/001206 WO1998049293A1 (en) | 1997-04-25 | 1998-04-24 | Human theta subunit of the gaba-a receptor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE300612T1 true ATE300612T1 (de) | 2005-08-15 |
Family
ID=10811405
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98917470T ATE300612T1 (de) | 1997-04-25 | 1998-04-24 | Theta-untereinheit des menschlichen gaba-a rezeptors |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6555341B1 (de) |
| EP (1) | EP0977848B1 (de) |
| JP (1) | JP2002501382A (de) |
| AT (1) | ATE300612T1 (de) |
| AU (1) | AU7069498A (de) |
| CA (1) | CA2287782A1 (de) |
| DE (1) | DE69830989T2 (de) |
| DK (1) | DK0977848T3 (de) |
| ES (1) | ES2244057T3 (de) |
| GB (1) | GB9708479D0 (de) |
| WO (1) | WO1998049293A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU7151601A (en) | 2000-06-27 | 2002-01-08 | Lexicon Genetics Inc | Novel human gaba receptors and polynucleotides encoding the same |
| EP1500703A3 (de) * | 2000-06-27 | 2005-02-16 | Lexicon Genetics Incorporated | Menschliche Gaba-rezeptoren und für diese kodierende Polynukleotide |
| WO2007002359A2 (en) * | 2005-06-24 | 2007-01-04 | The Regents Of The University Of California | Methods for identifying delta subunit-containing gaba receptor modulatory agents |
| CN101960014B (zh) * | 2008-02-01 | 2013-10-16 | 克罗莫塞尔公司 | 细胞系以及制备和使用其的方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2296064T3 (es) * | 1992-12-10 | 2008-04-16 | MERCK SHARP & DOHME LIMITED | Lineas celulares transfectadas de manera estable que expresan receptores gaba-a humanos con una combinacion de subunidades alfa-2, beta-3 y gamma-2. |
| GB9408064D0 (en) * | 1994-04-22 | 1994-06-15 | Merck Sharp & Dohme | Nucleic acids |
-
1997
- 1997-04-25 GB GBGB9708479.2A patent/GB9708479D0/en active Pending
-
1998
- 1998-04-24 DE DE69830989T patent/DE69830989T2/de not_active Expired - Fee Related
- 1998-04-24 AU AU70694/98A patent/AU7069498A/en not_active Abandoned
- 1998-04-24 AT AT98917470T patent/ATE300612T1/de not_active IP Right Cessation
- 1998-04-24 JP JP54672598A patent/JP2002501382A/ja not_active Ceased
- 1998-04-24 WO PCT/GB1998/001206 patent/WO1998049293A1/en active IP Right Grant
- 1998-04-24 CA CA002287782A patent/CA2287782A1/en not_active Abandoned
- 1998-04-24 EP EP98917470A patent/EP0977848B1/de not_active Expired - Lifetime
- 1998-04-24 DK DK98917470T patent/DK0977848T3/da active
- 1998-04-24 US US09/403,667 patent/US6555341B1/en not_active Expired - Fee Related
- 1998-04-24 ES ES98917470T patent/ES2244057T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO1998049293A1 (en) | 1998-11-05 |
| AU7069498A (en) | 1998-11-24 |
| ES2244057T3 (es) | 2005-12-01 |
| DE69830989D1 (de) | 2005-09-01 |
| GB9708479D0 (en) | 1997-06-18 |
| JP2002501382A (ja) | 2002-01-15 |
| EP0977848B1 (de) | 2005-07-27 |
| US6555341B1 (en) | 2003-04-29 |
| EP0977848A1 (de) | 2000-02-09 |
| DK0977848T3 (da) | 2005-11-14 |
| DE69830989T2 (de) | 2006-04-20 |
| CA2287782A1 (en) | 1998-11-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |