ATE299510T1 - Peptide als kalium kanalaktivatoren - Google Patents
Peptide als kalium kanalaktivatorenInfo
- Publication number
- ATE299510T1 ATE299510T1 AT98939267T AT98939267T ATE299510T1 AT E299510 T1 ATE299510 T1 AT E299510T1 AT 98939267 T AT98939267 T AT 98939267T AT 98939267 T AT98939267 T AT 98939267T AT E299510 T1 ATE299510 T1 AT E299510T1
- Authority
- AT
- Austria
- Prior art keywords
- peptides
- potassium channel
- channel activators
- potassium
- prophylactic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/07—Tetrapeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
- C07K5/06052—Val-amino acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/908,328 US5972894A (en) | 1997-08-07 | 1997-08-07 | Peptides having potassium channel opener activity |
PCT/US1998/016405 WO1999007729A2 (en) | 1997-08-07 | 1998-08-06 | Peptides having potassium channel opener activity |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE299510T1 true ATE299510T1 (de) | 2005-07-15 |
Family
ID=25425604
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT98939267T ATE299510T1 (de) | 1997-08-07 | 1998-08-06 | Peptide als kalium kanalaktivatoren |
Country Status (10)
Country | Link |
---|---|
US (1) | US5972894A (de) |
EP (1) | EP1001976B1 (de) |
JP (1) | JP2001512740A (de) |
AT (1) | ATE299510T1 (de) |
AU (1) | AU731793B2 (de) |
CA (1) | CA2301669A1 (de) |
DE (1) | DE69830842T9 (de) |
ES (1) | ES2246072T3 (de) |
TW (1) | TWI230613B (de) |
WO (1) | WO1999007729A2 (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2001265841A1 (en) * | 2000-06-26 | 2002-01-08 | Novo-Nordisk A/S | Use of potassium channel openers for the treatment of insulitis |
CN1135983C (zh) * | 2001-06-28 | 2004-01-28 | 中山大学 | 二酸(5-雄甾烯-17-酮-3β-羟基)二酯用于制备药物 |
GB0206711D0 (en) | 2002-03-21 | 2002-05-01 | Isis Innovation | HIF Inhibitor |
US7585523B2 (en) * | 2002-08-27 | 2009-09-08 | Targeted Medical Pharma | Composition and method to augment and sustain neurotransmitter production |
WO2005018316A1 (ja) * | 2003-08-22 | 2005-03-03 | Yasumi Uchida | 肥大型心筋症モデル動物 |
JP2007504202A (ja) * | 2003-09-04 | 2007-03-01 | ポセイドン ファーマシュティカルズ アクティーゼルスカブ | 心臓不整脈を治療するためのergチャネル開口薬 |
US20060263805A1 (en) * | 2005-03-16 | 2006-11-23 | Andre Terzic | Diagnosing and treating potassium channel defects |
CN108272782B (zh) * | 2011-09-06 | 2021-04-23 | 库尔纳公司 | 小分子在制备治疗Dravet综合征或全面性癫痫伴热性惊厥附加症的药物中的用途 |
CN104736552B (zh) * | 2012-08-24 | 2018-04-06 | 庆熙大学校产学协力团 | 用于预防或治疗心血管疾病的、包含对血管紧张素‑i转换酶表现出抑制活性的肽作为活性成分的药物组合物 |
US9925233B2 (en) | 2015-01-30 | 2018-03-27 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
US9744209B2 (en) | 2015-01-30 | 2017-08-29 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
US9750785B2 (en) | 2015-01-30 | 2017-09-05 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
US9937223B2 (en) | 2015-01-30 | 2018-04-10 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
US9744239B2 (en) | 2015-01-30 | 2017-08-29 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
US9687526B2 (en) | 2015-01-30 | 2017-06-27 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
WO2021072350A1 (en) * | 2019-10-11 | 2021-04-15 | Tobebio Novel Drug Co., Ltd. | Synergistic combination of chemotherapy and peptide for treating cancer |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1489879A (en) * | 1974-12-20 | 1977-10-26 | Leo Pharm Prod Ltd | N'-cyano-n'-3-pyridylguanidines |
US4200640A (en) * | 1976-04-02 | 1980-04-29 | Chugai Seiyaku Kabushiki Kaisha | Nitric ester of N-(2-hydroxyethyl)nicotinamide and pharmaceutical use |
NO812612L (no) * | 1980-08-06 | 1982-02-08 | Ferring Pharma Ltd | Enzym-inhibitorer. |
SU1417242A1 (ru) * | 1985-10-28 | 1995-10-27 | Г.М. Яковлев | Способ получения вещества, восстанавливающего функцию миокарда |
GB9510477D0 (en) * | 1995-05-24 | 1995-07-19 | Sandoz Ltd | Organic compounds |
US5565483A (en) * | 1995-06-07 | 1996-10-15 | Bristol-Myers Squibb Company | 3-substituted oxindole derivatives as potassium channel modulators |
-
1997
- 1997-08-07 US US08/908,328 patent/US5972894A/en not_active Expired - Fee Related
-
1998
- 1998-08-06 CA CA002301669A patent/CA2301669A1/en not_active Abandoned
- 1998-08-06 AU AU87735/98A patent/AU731793B2/en not_active Ceased
- 1998-08-06 AT AT98939267T patent/ATE299510T1/de not_active IP Right Cessation
- 1998-08-06 JP JP2000506231A patent/JP2001512740A/ja active Pending
- 1998-08-06 WO PCT/US1998/016405 patent/WO1999007729A2/en active IP Right Grant
- 1998-08-06 DE DE69830842T patent/DE69830842T9/de not_active Expired - Fee Related
- 1998-08-06 ES ES98939267T patent/ES2246072T3/es not_active Expired - Lifetime
- 1998-08-06 EP EP98939267A patent/EP1001976B1/de not_active Expired - Lifetime
-
1999
- 1999-02-03 TW TW088101648A patent/TWI230613B/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CA2301669A1 (en) | 1999-02-18 |
JP2001512740A (ja) | 2001-08-28 |
ES2246072T3 (es) | 2006-02-01 |
WO1999007729A3 (en) | 1999-06-03 |
EP1001976B1 (de) | 2005-07-13 |
DE69830842T2 (de) | 2006-05-24 |
TWI230613B (en) | 2005-04-11 |
AU731793B2 (en) | 2001-04-05 |
EP1001976A2 (de) | 2000-05-24 |
AU8773598A (en) | 1999-03-01 |
WO1999007729A2 (en) | 1999-02-18 |
US5972894A (en) | 1999-10-26 |
DE69830842D1 (de) | 2005-08-18 |
DE69830842T9 (de) | 2007-01-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE299510T1 (de) | Peptide als kalium kanalaktivatoren | |
TR199901174T2 (xx) | Yeni heterosiklilmetil-ikameli pirazol t�revleri. | |
YU9404A (sh) | Multimerna, usmerena kontrastna sredstva na bazi peptida | |
IL132797A0 (en) | Compounds and methods for the inhibition of the expression of vcam-1 | |
IL148079A0 (en) | Human ctla-4 antibodies and compositions containing the same | |
HK1053989A1 (en) | Fused pyrrolocarbazoles against inflammation | |
EA200100589A1 (ru) | Азабициклоалканы как модуляторы ccr5 | |
MY129189A (en) | Prostaglandin agonists and their use to treat bone disorders | |
YU40701A (sh) | Piperidini kao modulatori ccr5 | |
CY1108610T1 (el) | Πεπτιδια της il-2 και παραγωγα αυτων και χρηση αυτων ως θεραπευτικοι παραγοντες | |
WO2004024097A8 (en) | Compositions and methods for the treatment of immune related diseases | |
AU2001235006A1 (en) | Prophylactic and therapeutic monoclonal antibodies | |
IL127918A0 (en) | Novel amino sugar and related sugar derivatives of indolylopyrrolocarbazoles their use as antitumor agents and pharmaceutical formulations | |
SE9802729D0 (sv) | Novel Compounds | |
DE69905476D1 (en) | Phosphonsaürederivate als ptp-1b-inhibitoren | |
AUPP589598A0 (en) | Novel peptides | |
ATE397062T1 (de) | Chimäre polypeptide, die das fragment b des shigatoxins sowie peptide von therapeutischem interesse enthalten | |
ZA951974B (en) | Bradykinin antagonist peptides incorporating N-subsituted glycines | |
PL374080A1 (en) | Processes for the preparation of fibrinogen | |
MXPA01010403A (es) | Agentes quimiotacticos e inhibidores derivados de osteopontina y usos de los mismos. | |
PA8577701A1 (es) | Polipeptido t20 pegilado | |
AU7216498A (en) | Inhibitors of the urokinase receptor | |
MY127474A (en) | Naphthyl compounds, intermediates, compositions, and methods of use | |
ATE390440T1 (de) | Neuroaktive peptide | |
DK1039931T3 (da) | Multivalente rekombinante antistoffer til at behandle HRV infektioner |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 1001976 Country of ref document: EP |
|
REN | Ceased due to non-payment of the annual fee |