ATE291915T1 - Verwendung von retinsäure-rezeptor-agonisten oder ap-1-antagonisten zur herstellung eines medikaments zur prävention der proliferation des retinalen pigmentepithels - Google Patents

Verwendung von retinsäure-rezeptor-agonisten oder ap-1-antagonisten zur herstellung eines medikaments zur prävention der proliferation des retinalen pigmentepithels

Info

Publication number
ATE291915T1
ATE291915T1 AT96902791T AT96902791T ATE291915T1 AT E291915 T1 ATE291915 T1 AT E291915T1 AT 96902791 T AT96902791 T AT 96902791T AT 96902791 T AT96902791 T AT 96902791T AT E291915 T1 ATE291915 T1 AT E291915T1
Authority
AT
Austria
Prior art keywords
retinal
retinal pigment
proliferation
acid receptor
medication
Prior art date
Application number
AT96902791T
Other languages
English (en)
Inventor
Peter A Campochiaro
Larry A Wheeler
Roshantha A Chandraratna
Sunil Nagpal
Juan Eugene De Jr
Original Assignee
Univ Johns Hopkins Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Johns Hopkins Med filed Critical Univ Johns Hopkins Med
Application granted granted Critical
Publication of ATE291915T1 publication Critical patent/ATE291915T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
AT96902791T 1995-02-01 1996-01-31 Verwendung von retinsäure-rezeptor-agonisten oder ap-1-antagonisten zur herstellung eines medikaments zur prävention der proliferation des retinalen pigmentepithels ATE291915T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/383,741 US5824685A (en) 1995-02-01 1995-02-01 Method of preventing proliferation of retinal pigment epithelium by retinoic acid receptor agonists
PCT/US1996/001505 WO1996023498A1 (en) 1995-02-01 1996-01-31 Method of preventing proliferation of retinal pigment epithelium by retinoic acid receptor agonists

Publications (1)

Publication Number Publication Date
ATE291915T1 true ATE291915T1 (de) 2005-04-15

Family

ID=23514507

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96902791T ATE291915T1 (de) 1995-02-01 1996-01-31 Verwendung von retinsäure-rezeptor-agonisten oder ap-1-antagonisten zur herstellung eines medikaments zur prävention der proliferation des retinalen pigmentepithels

Country Status (7)

Country Link
US (5) US5824685A (de)
EP (1) EP0804194B1 (de)
JP (1) JP4121552B2 (de)
AT (1) ATE291915T1 (de)
AU (1) AU4707096A (de)
DE (1) DE69634532T2 (de)
WO (1) WO1996023498A1 (de)

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US20030113281A1 (en) * 1998-05-06 2003-06-19 Galderma Research & Development, S.N.C. Assay for identification of compounds that promote melanin production and retinoid-like compounds identified by said assay
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US20030229062A1 (en) * 2001-12-07 2003-12-11 The Regents Of The University Of California Treatments for age-related macular degeneration (AMD)
WO2003049685A2 (en) * 2001-12-07 2003-06-19 The Regents Of The University Of California Treatment for age-related macular degeneration
US7470659B2 (en) * 2001-12-07 2008-12-30 The Regents Of The University Of California Methods to increase reverse cholesterol transport in the retinal pigment epithelium (RPE) and Bruch's membrane (BM)
WO2004028477A2 (en) * 2002-09-29 2004-04-08 Surmodics, Inc. Methods for treatment and/or prevention of retinal disease
US20060172972A1 (en) * 2002-12-20 2006-08-03 Chakshu Research Inc Formulation and method for administration of ophthalmologically active agents
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US7070554B2 (en) 2003-01-15 2006-07-04 Theragenics Corporation Brachytherapy devices and methods of using them
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US20050009910A1 (en) * 2003-07-10 2005-01-13 Allergan, Inc. Delivery of an active drug to the posterior part of the eye via subconjunctival or periocular delivery of a prodrug
US7407973B2 (en) * 2003-10-24 2008-08-05 Intermune, Inc. Use of pirfenidone in therapeutic regimens
CN1889954A (zh) * 2003-12-02 2007-01-03 阿勒根公司 用类维生素a预防和/或减轻光受体变性的方法
US20080176952A1 (en) * 2004-02-17 2008-07-24 Rando Robert R Management of Ophthalmologic Disorders, Including Macular Degeneration
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AU2005240078A1 (en) * 2004-04-30 2005-11-17 Allergan, Inc. Retinoid-containing sustained release intraocular drug delivery systems and related methods of manufacturing
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WO2006014484A2 (en) * 2004-07-02 2006-02-09 Surmodics, Inc. Methods and devices for the treatment of ocular conditions
US20060020037A1 (en) * 2004-07-22 2006-01-26 Allergan, Inc. Tazarotenic acid and esters thereof for treating autism
US7597884B2 (en) 2004-08-09 2009-10-06 Alios Biopharma, Inc. Hyperglycosylated polypeptide variants and methods of use
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Also Published As

Publication number Publication date
US5824685A (en) 1998-10-20
US6573271B2 (en) 2003-06-03
JPH11503998A (ja) 1999-04-06
EP0804194A1 (de) 1997-11-05
AU4707096A (en) 1996-08-21
US20020128291A1 (en) 2002-09-12
JP4121552B2 (ja) 2008-07-23
DE69634532T2 (de) 2006-02-23
US6075032A (en) 2000-06-13
EP0804194B1 (de) 2005-03-30
US6372753B1 (en) 2002-04-16
US6071924A (en) 2000-06-06
EP0804194A4 (de) 2001-01-17
DE69634532D1 (de) 2005-05-04
WO1996023498A1 (en) 1996-08-08

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