ATE290868T1 - Verwendung von 19-nor-vitamin-d-verbindungen zur vorbeugung von hyperphosphatemie bei nierenkrankheiten - Google Patents
Verwendung von 19-nor-vitamin-d-verbindungen zur vorbeugung von hyperphosphatemie bei nierenkrankheitenInfo
- Publication number
- ATE290868T1 ATE290868T1 AT96926066T AT96926066T ATE290868T1 AT E290868 T1 ATE290868 T1 AT E290868T1 AT 96926066 T AT96926066 T AT 96926066T AT 96926066 T AT96926066 T AT 96926066T AT E290868 T1 ATE290868 T1 AT E290868T1
- Authority
- AT
- Austria
- Prior art keywords
- vitamin
- compounds
- kidney disease
- analogs
- pth
- Prior art date
Links
- PKFBWEUIKKCWEW-WEZTXPJVSA-N (1r,3r)-5-[(2e)-2-[(1r,3as,7ar)-1-[(2r)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1h-inden-4-ylidene]ethylidene]cyclohexane-1,3-diol Chemical class C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@@H](CCCC(C)(C)O)C)=C\C=C1C[C@@H](O)C[C@H](O)C1 PKFBWEUIKKCWEW-WEZTXPJVSA-N 0.000 title abstract 2
- 208000017169 kidney disease Diseases 0.000 title abstract 2
- 201000005991 hyperphosphatemia Diseases 0.000 title 1
- 102000003982 Parathyroid hormone Human genes 0.000 abstract 3
- 108090000445 Parathyroid hormone Proteins 0.000 abstract 3
- 239000000199 parathyroid hormone Substances 0.000 abstract 3
- 229960001319 parathyroid hormone Drugs 0.000 abstract 3
- 210000002966 serum Anatomy 0.000 abstract 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 abstract 1
- 208000005770 Secondary Hyperparathyroidism Diseases 0.000 abstract 1
- 230000000125 calcaemic effect Effects 0.000 abstract 1
- 239000011575 calcium Substances 0.000 abstract 1
- 229910052791 calcium Inorganic materials 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 201000006370 kidney failure Diseases 0.000 abstract 1
- BPKAHTKRCLCHEA-UBFJEZKGSA-N paricalcitol Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@@H](\C=C\[C@H](C)C(C)(C)O)C)=C\C=C1C[C@@H](O)C[C@H](O)C1 BPKAHTKRCLCHEA-UBFJEZKGSA-N 0.000 abstract 1
- 230000003173 phosphatemic effect Effects 0.000 abstract 1
- 239000011574 phosphorus Substances 0.000 abstract 1
- 229910052698 phosphorus Inorganic materials 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/592—9,10-Secoergostane derivatives, e.g. ergocalciferol, i.e. vitamin D2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Rheumatology (AREA)
- Nutrition Science (AREA)
- Urology & Nephrology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/502,288 US5597815A (en) | 1995-07-13 | 1995-07-13 | Prevention of hyperphosphatemia in kidney disorder patients |
| PCT/US1996/011486 WO1997002826A2 (en) | 1995-07-13 | 1996-07-09 | Use of 19-nor-vitamin d compounds for the prevention of hyperphosphatemia in kidney disorder patients |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE290868T1 true ATE290868T1 (de) | 2005-04-15 |
Family
ID=23997158
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96926066T ATE290868T1 (de) | 1995-07-13 | 1996-07-09 | Verwendung von 19-nor-vitamin-d-verbindungen zur vorbeugung von hyperphosphatemie bei nierenkrankheiten |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5597815A (de) |
| EP (1) | EP0837681B1 (de) |
| JP (1) | JP3255926B2 (de) |
| AT (1) | ATE290868T1 (de) |
| AU (1) | AU705895B2 (de) |
| CA (1) | CA2224284C (de) |
| DE (1) | DE69634483T2 (de) |
| DK (1) | DK0837681T3 (de) |
| ES (1) | ES2236742T3 (de) |
| NZ (1) | NZ313816A (de) |
| PT (1) | PT837681E (de) |
| WO (1) | WO1997002826A2 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU7817298A (en) * | 1997-06-06 | 1998-12-21 | Wisconsin Alumni Research Foundation | Use of vitamin d compounds to prevent transplant rejection |
| US6359152B2 (en) | 1997-07-21 | 2002-03-19 | Wisconsin Alumni Research Foundation | 18-substituted-19-nor-vitamin D compounds |
| US5939406A (en) * | 1997-07-21 | 1999-08-17 | Wisconsin Alumni Research Foundation | 18-substituted-19-nor-vitamin D compounds |
| US6136799A (en) * | 1998-04-08 | 2000-10-24 | Abbott Laboratories | Cosolvent formulations |
| DE69913092T2 (de) * | 1999-01-27 | 2004-09-09 | Commissariat à l'Energie Atomique | Microassay zur Serienanalyse der Genexpression und Anwendungen davon |
| CA2420759A1 (en) * | 2000-08-30 | 2003-02-27 | Daishiro Miura | Parathyroid hormone production inhibitors containing vitamin d3 derivatives |
| US7129230B2 (en) | 2001-03-12 | 2006-10-31 | Nestec S.A. | Method and product for treating cancer in pets |
| US6887897B2 (en) | 2001-07-31 | 2005-05-03 | Mission Pharmacal Company | Calcium glutarate supplement and phosphorus binder |
| EP1583539A2 (de) * | 2003-01-13 | 2005-10-12 | Cedars-Sinai Medical Center | Paricalcitol als chemotherapeutikum |
| US20050148557A1 (en) * | 2003-07-29 | 2005-07-07 | Jin Tian | Use of Vitamin Ds to treat kidney disease |
| ES2573636T3 (es) * | 2006-10-25 | 2016-06-09 | Wisconsin Alumni Research Foundation | Métodos para reducir la absorción de fosfato empleando un anticuerpo anti-Npt2B |
| US9198923B2 (en) * | 2009-01-26 | 2015-12-01 | Opko Ireland Global Holdings, Ltd. | Phosphate management with small molecules |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1333616C (en) * | 1989-03-09 | 1994-12-20 | Hector F. Deluca | 19-nor-vitamin d compounds |
| US5246925A (en) * | 1989-03-09 | 1993-09-21 | Wisconsin Alumni Research Foundation | 19-nor-vitamin D compounds for use in treating hyperparathyroidism |
| NZ232734A (en) * | 1989-03-09 | 1991-11-26 | Wisconsin Alumni Res Found | 19-nor vitamin d derivatives and pharmaceutical compositions |
| GB2229921B (en) * | 1989-04-05 | 1992-12-16 | Chugai Pharmaceutical Co Ltd | Treatment for hyperparathyroidism with use of vitamin d derivatives |
| AU650751B2 (en) * | 1991-05-28 | 1994-06-30 | Wisconsin Alumni Research Foundation | Novel synthesis of 19-nor vitamin D compounds |
| US5086191A (en) * | 1991-05-28 | 1992-02-04 | Wisconsin Alumni Research Foundation | Intermediates for the synthesis of 19-nor vitamin D compounds |
-
1995
- 1995-07-13 US US08/502,288 patent/US5597815A/en not_active Expired - Lifetime
-
1996
- 1996-07-09 NZ NZ313816A patent/NZ313816A/en not_active IP Right Cessation
- 1996-07-09 WO PCT/US1996/011486 patent/WO1997002826A2/en active IP Right Grant
- 1996-07-09 AT AT96926066T patent/ATE290868T1/de active
- 1996-07-09 DE DE69634483T patent/DE69634483T2/de not_active Expired - Lifetime
- 1996-07-09 ES ES96926066T patent/ES2236742T3/es not_active Expired - Lifetime
- 1996-07-09 EP EP96926066A patent/EP0837681B1/de not_active Expired - Lifetime
- 1996-07-09 AU AU66364/96A patent/AU705895B2/en not_active Expired
- 1996-07-09 JP JP50595697A patent/JP3255926B2/ja not_active Expired - Lifetime
- 1996-07-09 DK DK96926066T patent/DK0837681T3/da active
- 1996-07-09 PT PT96926066T patent/PT837681E/pt unknown
- 1996-07-09 CA CA002224284A patent/CA2224284C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69634483T2 (de) | 2006-04-13 |
| EP0837681A2 (de) | 1998-04-29 |
| DK0837681T3 (da) | 2005-06-13 |
| WO1997002826A2 (en) | 1997-01-30 |
| WO1997002826A3 (en) | 1997-03-13 |
| EP0837681B1 (de) | 2005-03-16 |
| DE69634483D1 (de) | 2005-04-21 |
| CA2224284A1 (en) | 1997-01-30 |
| AU705895B2 (en) | 1999-06-03 |
| NZ313816A (en) | 2001-06-29 |
| PT837681E (pt) | 2005-06-30 |
| AU6636496A (en) | 1997-02-10 |
| ES2236742T3 (es) | 2005-07-16 |
| MX9800342A (es) | 1998-07-31 |
| US5597815A (en) | 1997-01-28 |
| JPH11502862A (ja) | 1999-03-09 |
| JP3255926B2 (ja) | 2002-02-12 |
| CA2224284C (en) | 2003-12-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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