ATE290351T1 - BIOAKTIVER ABBAUBARER VERBUNDSTOFF FÜR ßTISSUE ENGINEERINGß - Google Patents

BIOAKTIVER ABBAUBARER VERBUNDSTOFF FÜR ßTISSUE ENGINEERINGß

Info

Publication number
ATE290351T1
ATE290351T1 AT00991390T AT00991390T ATE290351T1 AT E290351 T1 ATE290351 T1 AT E290351T1 AT 00991390 T AT00991390 T AT 00991390T AT 00991390 T AT00991390 T AT 00991390T AT E290351 T1 ATE290351 T1 AT E290351T1
Authority
AT
Austria
Prior art keywords
ßtissue
engineeringß
degradable composite
bioactive
bioactive degradable
Prior art date
Application number
AT00991390T
Other languages
English (en)
Inventor
Paul Ducheyne
Portonovo S Ayyaswamy
Qing-Qing Qui
Original Assignee
Univ Pennsylvania
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pennsylvania filed Critical Univ Pennsylvania
Application granted granted Critical
Publication of ATE290351T1 publication Critical patent/ATE290351T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C4/00—Compositions for glass with special properties
    • C03C4/0007—Compositions for glass with special properties for biologically-compatible glass
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/30—Inorganic materials
    • A61L27/32—Phosphorus-containing materials, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/446—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with other specific inorganic fillers other than those covered by A61L27/443 or A61L27/46
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C12/00—Powdered glass; Bead compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/3006—Properties of materials and coating materials
    • A61F2002/30062—(bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30667—Features concerning an interaction with the environment or a particular use of the prosthesis
    • A61F2002/30677—Means for introducing or releasing pharmaceutical products, e.g. antibiotics, into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00179—Ceramics or ceramic-like structures
    • A61F2310/00293—Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite
AT00991390T 1999-11-12 2000-11-10 BIOAKTIVER ABBAUBARER VERBUNDSTOFF FÜR ßTISSUE ENGINEERINGß ATE290351T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/439,183 US6328990B1 (en) 1999-11-12 1999-11-12 Bioactive, degradable composite for tissue engineering
PCT/US2000/030947 WO2001034060A1 (en) 1999-11-12 2000-11-10 Bioactive, degradable composite for tissue engineering

Publications (1)

Publication Number Publication Date
ATE290351T1 true ATE290351T1 (de) 2005-03-15

Family

ID=23743660

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00991390T ATE290351T1 (de) 1999-11-12 2000-11-10 BIOAKTIVER ABBAUBARER VERBUNDSTOFF FÜR ßTISSUE ENGINEERINGß

Country Status (8)

Country Link
US (1) US6328990B1 (de)
EP (1) EP1233721B1 (de)
JP (1) JP2003513701A (de)
AT (1) ATE290351T1 (de)
AU (1) AU774288B2 (de)
CA (1) CA2391232A1 (de)
DE (1) DE60018600T2 (de)
WO (1) WO2001034060A1 (de)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020155559A1 (en) * 2001-01-17 2002-10-24 Laurencin Cato T. Biocompatible, biodegradable polymer-based, lighter than or light as water scaffolds for tissue engineering and methods for preparation and use thereof
US6696575B2 (en) 2001-03-27 2004-02-24 Board Of Regents, The University Of Texas System Biodegradable, electrically conducting polymer for tissue engineering applications
CN1294885C (zh) * 2001-06-05 2007-01-17 江苏阳生生物工程有限公司 人体骨组织生物工程支架制品及其制备方法和用途
CA2451187C (en) 2001-06-22 2012-08-14 Southern Biosystems, Inc. Zero-order prolonged release coaxial implants
US20030220692A1 (en) * 2002-02-09 2003-11-27 Shapiro Irving M. Preparations of nucleus pulposus cells and methods for their generation, identification, and use
AU2003304348A1 (en) * 2002-03-15 2005-02-04 The Trustees Of The University Of Pennsylvania Fibrous composite for tissue engineering
AU2003251899A1 (en) * 2002-07-10 2004-01-23 University Of Florida Sol-gel derived bioactive glass polymer composite
US7066962B2 (en) * 2002-07-23 2006-06-27 Porex Surgical, Inc. Composite surgical implant made from macroporous synthetic resin and bioglass particles
AU2003287444A1 (en) * 2002-10-31 2004-05-25 The General Hospital Corporation Repairing or replacing tissues or organs
US20060140904A1 (en) * 2003-02-12 2006-06-29 Tadeusz Wellisz Random alkylene oxide copolymers for medical and surgical utilities
JP2007509716A (ja) * 2003-10-29 2007-04-19 ジェンティス インコーポレイテッド 組織工学用の重合可能なエマルション
US8012210B2 (en) 2004-01-16 2011-09-06 Warsaw Orthopedic, Inc. Implant frames for use with settable materials and related methods of use
CA2557231C (en) * 2004-03-05 2013-12-31 The Trustees Of Columbia University In The City Of New York Multi-phased, biodegradable and osteointegrative composite scaffold for biological fixation of musculoskeletal soft tissue to bone
US7189409B2 (en) * 2004-03-09 2007-03-13 Inion Ltd. Bone grafting material, method and implant
JP2006101986A (ja) * 2004-10-01 2006-04-20 Olympus Corp 球状セラミックス粒子の製造方法、細胞の播種方法および生体組織補填体の製造方法
WO2006137787A1 (en) * 2005-06-21 2006-12-28 Ge Healthcare Bio-Sciences Ab Method for cell culture
US20070148251A1 (en) 2005-12-22 2007-06-28 Hossainy Syed F A Nanoparticle releasing medical devices
AU2007207429A1 (en) 2006-01-19 2007-07-26 Warsaw Orthopedic, Inc. Injectable and moldable bone substitute materials
US9034356B2 (en) 2006-01-19 2015-05-19 Warsaw Orthopedic, Inc. Porous osteoimplant
US20070249044A1 (en) * 2006-01-30 2007-10-25 University Of Illinois At Chicago Microstructures in three dimensional gel suspensions for growth of cells
AU2007232187A1 (en) * 2006-03-31 2007-10-11 Csir Bulking of soft tissue
US20080081362A1 (en) * 2006-09-29 2008-04-03 Daniel Keeley Multilayered Composite for Organ Augmentation and Repair
US20080119927A1 (en) * 2006-11-17 2008-05-22 Medtronic Vascular, Inc. Stent Coating Including Therapeutic Biodegradable Glass, and Method of Making
CN101200532B (zh) * 2006-12-12 2011-04-27 上海杰事杰新材料股份有限公司 高分子量聚己内酯等可生物降解材料中空球的制备方法
US8753391B2 (en) 2007-02-12 2014-06-17 The Trustees Of Columbia University In The City Of New York Fully synthetic implantable multi-phased scaffold
WO2008130529A1 (en) * 2007-04-16 2008-10-30 University Of Toledo Hybrid biomimetic particles, methods of making same and uses therefor
US20100317112A1 (en) * 2007-04-27 2010-12-16 Hyunjin Yang Scaffolds increased specific gravity for cell culture and method for manufacturing thereof
EP2146756A2 (de) * 2007-05-22 2010-01-27 Cinvention Ag Teilweise abbaubare gerüste für biomedizinische anwendungen
DE102007031945A1 (de) * 2007-07-06 2009-01-08 Resoimplant Gmbh Bioresorbierbares Implantat
EP2179030B1 (de) 2007-07-12 2013-09-25 Discgenics Menschliches bandscheibengewebe
US8591933B2 (en) * 2007-07-18 2013-11-26 The Board Of Trustees Of The University Of Illinois Temporal release of growth factors from 3D micro rod scaffolds for tissue regeneration
CA2791716C (en) * 2010-03-03 2020-08-18 Novabone Products, Llc Devices and methods for the regeneration of bony defects
US9144629B2 (en) 2010-03-03 2015-09-29 Novabone Products, Llc Ionically crosslinked materials and methods for production
WO2015147923A1 (en) 2010-03-03 2015-10-01 Novabone Products, Llc Kit for delivering bone grafting materials
US10646514B2 (en) 2013-03-14 2020-05-12 Novabone Products, Llc Processing methods of solgel-derived bioactive glass-ceramic compositions and methods of using the same
EP2983643A4 (de) 2013-04-12 2016-12-28 Univ Columbia Verfahren für wirtszellen-homing und zahnmarkregeneration
US10676713B2 (en) 2016-05-27 2020-06-09 Corning Incorporated Bioactive borophosphate glasses
US10751367B2 (en) * 2016-05-27 2020-08-25 Corning Incorporated Bioactive glass microspheres
US10647962B2 (en) 2016-05-27 2020-05-12 Corning Incorporated Bioactive aluminoborate glasses
US20170342383A1 (en) 2016-05-27 2017-11-30 Corning Incorporated Lithium disilicate glass-ceramic compositions and methods thereof
WO2019108557A1 (en) 2017-11-28 2019-06-06 Corning Incorporated Bioactive borate glass and methods thereof
CN111405913A (zh) 2017-11-28 2020-07-10 康宁股份有限公司 生物活性玻璃组合物和牙本质超敏性修复
CN111417601A (zh) 2017-11-28 2020-07-14 康宁股份有限公司 化学强化的生物活性玻璃陶瓷
EP3717427A1 (de) 2017-11-28 2020-10-07 Corning Incorporated Bioaktives glas mit hoher liquidusviskosität
CN108283729B (zh) * 2018-01-31 2020-06-26 北京化工大学 具有可控镁离子释放行为的可注射骨修复材料及其制备方法
CN109265942B (zh) * 2018-08-16 2021-10-19 张海军 一种聚乳酸微球及其制备方法与应用
CN109331223B (zh) * 2018-09-25 2021-07-30 广州润虹医药科技股份有限公司 一种载药生物活性玻璃复合磷酸钙骨水泥及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2651320B2 (ja) * 1992-07-16 1997-09-10 田辺製薬株式会社 徐放性マイクロスフェア製剤の製造方法
US5626861A (en) * 1994-04-01 1997-05-06 Massachusetts Institute Of Technology Polymeric-hydroxyapatite bone composite
ATE242646T1 (de) * 1995-09-14 2003-06-15 Takiron Co Osteosynthetisches material, verbundwerkstoff für implantate und verfahren zu ihrer herstellung
US6224913B1 (en) * 1996-05-09 2001-05-01 The Trustees Of The University Of Pennsylvania Conditioning of bioactive glass surfaces in protein containing solutions
US5964807A (en) * 1996-08-08 1999-10-12 Trustees Of The University Of Pennsylvania Compositions and methods for intervertebral disc reformation
JP3451417B2 (ja) * 1996-08-12 2003-09-29 タキロン株式会社 バイオセラミックス含有セル構造体とその製造方法
US5977204A (en) * 1997-04-11 1999-11-02 Osteobiologics, Inc. Biodegradable implant material comprising bioactive ceramic
US5972384A (en) * 1997-10-01 1999-10-26 University Of Maryland, Baltimore Use of biologically active glass as a drug delivery system

Also Published As

Publication number Publication date
EP1233721A1 (de) 2002-08-28
EP1233721A4 (de) 2003-07-23
US6328990B1 (en) 2001-12-11
EP1233721B1 (de) 2005-03-09
DE60018600D1 (de) 2005-04-14
WO2001034060A1 (en) 2001-05-17
JP2003513701A (ja) 2003-04-15
AU3262301A (en) 2001-06-06
CA2391232A1 (en) 2001-05-17
DE60018600T2 (de) 2005-07-28
AU774288B2 (en) 2004-06-24

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