ATE290013T1 - Neutralsierungs-assay, das humane papillomavirus- ähnliche partikel verwendet - Google Patents

Neutralsierungs-assay, das humane papillomavirus- ähnliche partikel verwendet

Info

Publication number
ATE290013T1
ATE290013T1 AT99967436T AT99967436T ATE290013T1 AT E290013 T1 ATE290013 T1 AT E290013T1 AT 99967436 T AT99967436 T AT 99967436T AT 99967436 T AT99967436 T AT 99967436T AT E290013 T1 ATE290013 T1 AT E290013T1
Authority
AT
Austria
Prior art keywords
particles
human papillomavirus
neutralization assay
pseudovirions
vlp
Prior art date
Application number
AT99967436T
Other languages
English (en)
Inventor
Kathrin U Jansen
Mark D Yeager
Paul M Keller
Robert S Lowe
Miguel Aste-Amezaga
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of ATE290013T1 publication Critical patent/ATE290013T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/20011Papillomaviridae
    • C12N2710/20023Virus like particles [VLP]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/01DNA viruses
    • G01N2333/025Papovaviridae, e.g. papillomavirus, polyomavirus, SV40, BK virus, JC virus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT99967436T 1998-12-23 1999-12-20 Neutralsierungs-assay, das humane papillomavirus- ähnliche partikel verwendet ATE290013T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11338898P 1998-12-23 1998-12-23
PCT/US1999/030297 WO2000039151A1 (en) 1998-12-23 1999-12-20 Neutralizing assay using human papillomavirus virus-like particles

Publications (1)

Publication Number Publication Date
ATE290013T1 true ATE290013T1 (de) 2005-03-15

Family

ID=22349108

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99967436T ATE290013T1 (de) 1998-12-23 1999-12-20 Neutralsierungs-assay, das humane papillomavirus- ähnliche partikel verwendet

Country Status (8)

Country Link
EP (1) EP1140974B1 (de)
JP (1) JP2002535965A (de)
AT (1) ATE290013T1 (de)
AU (1) AU763853B2 (de)
CA (1) CA2355883A1 (de)
DE (1) DE69924007T2 (de)
ES (1) ES2237204T3 (de)
WO (1) WO2000039151A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2415763A1 (en) * 2000-07-07 2002-01-17 Merck & Co., Inc. Production of chimeric human papillomavirus
JP2004532012A (ja) * 2001-03-02 2004-10-21 メルク エンド カムパニー インコーポレーテッド ウイルスリポーター粒子
AU2003296902A1 (en) * 2002-09-03 2004-05-04 Kentucky Bioprocessing, Llc Production of peptides in plants as viral coat protein fusions
MY140664A (en) * 2003-09-29 2010-01-15 Merck Sharp & Dohme Optimized expression of hpv 45 l1 in yeast
US20130149696A1 (en) * 2010-06-02 2013-06-13 European Molecular Biology Laboratory High-throughput method for determining the presence of papillomavirus-neutralizing antibodies in a sample

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPM566794A0 (en) * 1994-05-17 1994-06-09 University Of Queensland, The Process and product
US5795754A (en) * 1995-07-19 1998-08-18 Merck & Co., Inc. Synthetic HPV11 virus-like particles
WO1998025646A1 (en) * 1996-12-09 1998-06-18 Merck & Co., Inc. Synthetic hpv16 virus-like particles

Also Published As

Publication number Publication date
DE69924007T2 (de) 2006-04-06
JP2002535965A (ja) 2002-10-29
DE69924007D1 (de) 2005-04-07
EP1140974A4 (de) 2003-06-11
AU763853B2 (en) 2003-07-31
AU2371000A (en) 2000-07-31
EP1140974B1 (de) 2005-03-02
WO2000039151A1 (en) 2000-07-06
ES2237204T3 (es) 2005-07-16
CA2355883A1 (en) 2000-07-06
EP1140974A1 (de) 2001-10-10

Similar Documents

Publication Publication Date Title
Becker et al. MC polyomavirus is frequently present in Merkel cell carcinoma of European patients
Frazer Development and implementation of papillomavirus prophylactic vaccines
JP2014012738A (ja) 免疫優性な共有黒色腫抗原を発現する黒色腫細胞株およびその使用方法
FR11C0022I2 (fr) Production de proteine de capside de virus du papillome humain et particules de type viral
CY1108106T1 (el) Χειμερικα μορια l1 ανθρωπινου θηλωματοϊου (hpv) και χρησεις τους
IL154566A0 (en) Diagnosis method of fibrotic disease using biochemical markers
Pfister Papillomaviruses: general description, taxonomy, and classification
WO2006075245A3 (en) Systems, methods, and compositions for detection of human papilloma virus in biological samples
EP2361930A3 (de) Multimere von peptide-mhc komplexen und deren verwendung in borrelia infektionskrankheiten
ATE417897T1 (de) Sulfonierte 8,9 benzophenoxazinfarbstoffe und die verwendung ihrer markierten konjugate
ATE290013T1 (de) Neutralsierungs-assay, das humane papillomavirus- ähnliche partikel verwendet
CN108918872A (zh) 一种检测凝血酶的纸基光致电化学免疫传感器的构建方法
EP1230932A3 (de) Verwendung von Antikörpern zur Vakzinierung gegen Krebs
DK1523497T3 (da) HSP 70 fra Arthrobacter
WO2001056456A3 (en) Methods and compositions for detection of disease
EP1309342A4 (de) Herstellung eines chimeren papillomavirus(22.01.2)
CN103645316A (zh) 一种基于链霉亲和素功能化半导体纳米材料的肿瘤标志物电化学免疫传感器及其制备方法
Fecek et al. Production of Alexa Fluor 488-labeled reovirus and characterization of target cell binding, competence, and immunogenicity of labeled virions
EP0863982A4 (de) Synthetische hpv11 virusartige partikel
DK0750669T3 (da) Modificeret papillomavirus-L2-protein og VLP'er dannet derudfra
ATE189897T1 (de) Antikörper gegen das prorenin profragment, reninaktive substanz die diese enthält und prorenintest die diese verwendet
Jacobelli et al. Anti-HPV16 E2 protein T-cell responses and viral control in women with usual vulvar intraepithelial neoplasia and their healthy partners
CN104132984B (zh) 单壁碳纳米角‑铂钯纳米粒和巨细胞病毒pp65抗体修饰电极及其制备方法和应用
Sapp et al. Synthesis, properties and applications of papillomavirus-like particles
Buyck Two remarkable new African Russula species with reddening context

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties