ATE287954T1 - Trägerprotein mit adjuvant aktivität, diese enthaltende immunogene komplexe, ihre herstellung,nukleotidsequenz und impfstoff - Google Patents
Trägerprotein mit adjuvant aktivität, diese enthaltende immunogene komplexe, ihre herstellung,nukleotidsequenz und impfstoffInfo
- Publication number
- ATE287954T1 ATE287954T1 AT95939335T AT95939335T ATE287954T1 AT E287954 T1 ATE287954 T1 AT E287954T1 AT 95939335 T AT95939335 T AT 95939335T AT 95939335 T AT95939335 T AT 95939335T AT E287954 T1 ATE287954 T1 AT E287954T1
- Authority
- AT
- Austria
- Prior art keywords
- vaccine
- production
- nucleotide sequence
- carrier protein
- complexes containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/26—Klebsiella (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6068—Other bacterial proteins, e.g. OMP
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18522—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/806—Antigenic peptides or proteins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/807—Hapten conjugated with peptide or protein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/82—Proteins from microorganisms
- Y10S530/825—Bacteria
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9413306A FR2726472B1 (fr) | 1994-11-07 | 1994-11-07 | Proteine porteuse a effet adjuvant, complexe immunogene la contenant, leur procede de preparation, sequence nucleotidique et vaccin |
PCT/FR1995/001463 WO1996014415A1 (fr) | 1994-11-07 | 1995-11-07 | Proteine porteuse a effet adjuvant, complexe immunogene la contenant, leur procede de preparation, sequence nucleotidique et vaccin |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE287954T1 true ATE287954T1 (de) | 2005-02-15 |
Family
ID=9468564
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT95939335T ATE287954T1 (de) | 1994-11-07 | 1995-11-07 | Trägerprotein mit adjuvant aktivität, diese enthaltende immunogene komplexe, ihre herstellung,nukleotidsequenz und impfstoff |
Country Status (14)
Country | Link |
---|---|
US (3) | US6197929B1 (de) |
EP (1) | EP0791063B1 (de) |
JP (1) | JPH10508595A (de) |
AT (1) | ATE287954T1 (de) |
AU (1) | AU714423B2 (de) |
CA (1) | CA2204510A1 (de) |
DE (1) | DE69533961T2 (de) |
DK (1) | DK0791063T3 (de) |
ES (1) | ES2236718T3 (de) |
FR (1) | FR2726472B1 (de) |
NZ (1) | NZ296561A (de) |
PT (1) | PT791063E (de) |
WO (1) | WO1996014415A1 (de) |
ZA (1) | ZA959416B (de) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2726472B1 (fr) | 1994-11-07 | 1997-01-31 | Pf Medicament | Proteine porteuse a effet adjuvant, complexe immunogene la contenant, leur procede de preparation, sequence nucleotidique et vaccin |
FR2748476B1 (fr) * | 1996-05-07 | 1998-08-14 | Pf Medicament | Complexe immunogene, son utilisation, son procede de preparation et vaccin le contenant |
FR2766192B1 (fr) * | 1997-07-17 | 2001-07-13 | Pf Medicament | Epitopes du vrs et anticorps les comportant, utiles dans le diagnostic et la therapie |
FR2776521B1 (fr) * | 1998-03-27 | 2000-12-15 | Pf Medicament | Utilisation de conjugues p40 actifs par voie nasale |
FR2785542B1 (fr) * | 1998-11-06 | 2001-02-09 | Pf Medicament | UTILISATION D'UNE PROTEINE OmpA D'ENTEROBACTERIE, POUR LE CIBLAGE SPECIFIQUE D'UNE SUBSTANCE BIOLOGIQUEMENT ACTIVE QUI LUI EST ASSOCIEE VERS LES CELLULES PRESENTATRICES D'ANTIGENES TELLES QUE LES CELLULES DENDRITIQUES HUMAINES |
FR2789588B1 (fr) * | 1999-02-17 | 2001-05-04 | Pf Medicament | Utilisation d'une proteine ompa d'enterobacterie associee a un antigene dans une composition pharmaceutique destinee a generer ou accroitre une reponse cytotoxique antivirale, antiparasitaire ou antitumorale |
FR2789902A1 (fr) * | 1999-02-24 | 2000-08-25 | Pf Medicament | PROTEINE OmpA DE KLEBSIELLA PNEUMONIAE ASSOCIEE A LA CHAINE BETA DE L'HORMONE hCG OU A UN COMPOSE IMPLIQUE DANS LA PROLIFERATION DE CELLULES TUMORALES OU DANS LA FERTILITE, UTILE DANS UNE COMPOSITION PHARMACEUTIQUE |
FR2790960B1 (fr) * | 1999-03-15 | 2002-10-31 | Pf Medicament | Utilisation de fractions membranaires bacteriennes a activite immunostimulante dans le traitement de cancers, leurs procedes de preparation et les compositions pharmaceutiques les contenant |
FR2790959B1 (fr) * | 1999-03-15 | 2003-06-27 | Pf Medicament | Utilisation de fractions membranaires bacteriennes a effet adjuvant, leurs procedes de preparation et composition pharmaceutique les contenant |
FR2798857B1 (fr) * | 1999-09-23 | 2003-06-06 | Pf Medicament | Utilisation d'une proteine de membrane ompa d'enterobacterie associee a un peptide immunogene du vrs pour la preparation de vaccins administrables par voie nasale |
FR2803302B1 (fr) | 2000-01-04 | 2004-12-10 | Pf Medicament | Procede de preparation d'un polypeptide soluble en solvant aqueux en absence de detergent |
FR2808445A1 (fr) * | 2000-05-04 | 2001-11-09 | Pf Medicament | Proteine omp associee a un lysat de cellules tumorales autologues et/ou heterologues |
FR2809014A1 (fr) * | 2000-05-16 | 2001-11-23 | Pf Medicament | Utilisation d'une proteine ompa d'enterobacterie comme agent antimicrobien |
FR2816844A1 (fr) * | 2000-11-17 | 2002-05-24 | Pf Medicament | Domaine periplasmique d'une proteine omp d'enterobacterie et son utilisation comme porteur et/ou adjuvant |
FR2828106A1 (fr) * | 2001-08-02 | 2003-02-07 | Pf Medicament | Utilisation d'une omp d'enterobacterie de faible masse moleculaire comme porteur et/ou adjuvant |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR0137963B1 (ko) * | 1987-12-23 | 1998-04-30 | 로버트 에이. 아미테이지 | 인간의 호흡기 합포체성 바이러스에 대한 당단백질 면역 단편을 함유하는 키메라(chimeric) 당단백질 |
WO1992004375A1 (en) * | 1990-08-31 | 1992-03-19 | The Upjohn Company | Hrsv vaccine |
GB9200117D0 (en) * | 1992-01-06 | 1992-02-26 | Connaught Lab | Production of recombinant chimeric proteins for vaccine use |
FR2718452B1 (fr) * | 1994-04-06 | 1996-06-28 | Pf Medicament | Elément d'immunogène, agent immunogène, composition pharmaceutique et procédé de préparation. |
US6019982A (en) * | 1994-08-26 | 2000-02-01 | The Administrators Of The Tulane Educational Fund | Mutant enterotoxin effective as a non-toxic oral adjuvant |
FR2726472B1 (fr) * | 1994-11-07 | 1997-01-31 | Pf Medicament | Proteine porteuse a effet adjuvant, complexe immunogene la contenant, leur procede de preparation, sequence nucleotidique et vaccin |
-
1994
- 1994-11-07 FR FR9413306A patent/FR2726472B1/fr not_active Expired - Fee Related
-
1995
- 1995-11-07 EP EP95939335A patent/EP0791063B1/de not_active Expired - Lifetime
- 1995-11-07 DK DK95939335T patent/DK0791063T3/da active
- 1995-11-07 JP JP8515107A patent/JPH10508595A/ja active Pending
- 1995-11-07 AT AT95939335T patent/ATE287954T1/de not_active IP Right Cessation
- 1995-11-07 ZA ZA959416A patent/ZA959416B/xx unknown
- 1995-11-07 CA CA002204510A patent/CA2204510A1/fr not_active Abandoned
- 1995-11-07 WO PCT/FR1995/001463 patent/WO1996014415A1/fr active IP Right Grant
- 1995-11-07 NZ NZ296561A patent/NZ296561A/xx unknown
- 1995-11-07 ES ES95939335T patent/ES2236718T3/es not_active Expired - Lifetime
- 1995-11-07 PT PT95939335T patent/PT791063E/pt unknown
- 1995-11-07 DE DE69533961T patent/DE69533961T2/de not_active Expired - Fee Related
- 1995-11-07 US US08/836,500 patent/US6197929B1/en not_active Expired - Fee Related
- 1995-11-07 AU AU41199/96A patent/AU714423B2/en not_active Ceased
-
2000
- 2000-10-05 US US09/679,750 patent/US6780420B1/en not_active Expired - Fee Related
-
2004
- 2004-04-01 US US10/815,320 patent/US7408044B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JPH10508595A (ja) | 1998-08-25 |
CA2204510A1 (fr) | 1996-05-17 |
AU4119996A (en) | 1996-05-31 |
NZ296561A (en) | 2000-01-28 |
ZA959416B (en) | 1996-06-06 |
US6197929B1 (en) | 2001-03-06 |
US6780420B1 (en) | 2004-08-24 |
FR2726472B1 (fr) | 1997-01-31 |
WO1996014415A1 (fr) | 1996-05-17 |
PT791063E (pt) | 2005-06-30 |
ES2236718T3 (es) | 2005-07-16 |
EP0791063A1 (de) | 1997-08-27 |
DE69533961T2 (de) | 2006-01-05 |
US7408044B2 (en) | 2008-08-05 |
FR2726472A1 (fr) | 1996-05-10 |
US20060034870A1 (en) | 2006-02-16 |
DK0791063T3 (da) | 2005-06-06 |
EP0791063B1 (de) | 2005-01-26 |
DE69533961D1 (de) | 2005-03-03 |
AU714423B2 (en) | 2000-01-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 0791063 Country of ref document: EP |
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REN | Ceased due to non-payment of the annual fee |