ATE281455T1 - Oxindolderivate - Google Patents
OxindolderivateInfo
- Publication number
- ATE281455T1 ATE281455T1 AT01950642T AT01950642T ATE281455T1 AT E281455 T1 ATE281455 T1 AT E281455T1 AT 01950642 T AT01950642 T AT 01950642T AT 01950642 T AT01950642 T AT 01950642T AT E281455 T1 ATE281455 T1 AT E281455T1
- Authority
- AT
- Austria
- Prior art keywords
- derivatives
- oxindol derivatives
- oxindol
- oxindole derivatives
- methods
- Prior art date
Links
- JYGFTBXVXVMTGB-UHFFFAOYSA-N indolin-2-one Chemical class C1=CC=C2NC(=O)CC2=C1 JYGFTBXVXVMTGB-UHFFFAOYSA-N 0.000 title 1
- 125000004095 oxindolyl group Chemical class N1(C(CC2=CC=CC=C12)=O)* 0.000 abstract 2
- 102000013701 Cyclin-Dependent Kinase 4 Human genes 0.000 abstract 1
- 108010025464 Cyclin-Dependent Kinase 4 Proteins 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000003463 hyperproliferative effect Effects 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- WCUZQRJNLHUKTA-UHFFFAOYSA-N pyrrolo[3,2-f]quinolin-2-one Chemical class C1=CN=C2C=CC3=NC(=O)C=C3C2=C1 WCUZQRJNLHUKTA-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23024100P | 2000-09-01 | 2000-09-01 | |
| PCT/US2001/020703 WO2002020524A1 (en) | 2000-09-01 | 2001-06-28 | Oxindole derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE281455T1 true ATE281455T1 (de) | 2004-11-15 |
Family
ID=22864461
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01950642T ATE281455T1 (de) | 2000-09-01 | 2001-06-28 | Oxindolderivate |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6720332B2 (enExample) |
| EP (1) | EP1313732B1 (enExample) |
| JP (1) | JP2004508372A (enExample) |
| AT (1) | ATE281455T1 (enExample) |
| AU (1) | AU2001271611A1 (enExample) |
| DE (1) | DE60106947T2 (enExample) |
| ES (1) | ES2230337T3 (enExample) |
| WO (1) | WO2002020524A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE420636T1 (de) * | 1999-05-19 | 2009-01-15 | Painceptor Pharma Corp | Hemmer der protonenabhängigen kationenkanäle und deren verwendung in der behandlung von ischemiebedingten erkrankungen |
| KR20060111716A (ko) | 2002-01-22 | 2006-10-27 | 워너-램버트 캄파니 엘엘씨 | 2-(피리딘-2-일아미노)-피리도[2,3-ｄ]피리미딘-7-온 |
| PL1648889T3 (pl) * | 2003-07-11 | 2009-03-31 | Warner Lambert Co | Sól izetionian selektywnego inhibitora CDK4 |
| EP1699477A2 (en) * | 2003-12-11 | 2006-09-13 | Theravance, Inc. | Compositions for use in the treatment of mutant receptor tyrosine kinase driven cellular proliferative diseases |
| US7304074B2 (en) * | 2005-04-05 | 2007-12-04 | Hoffmann-La Roche Inc. | Substituted 1,5-naphthyridine azolinones |
| EP2580320B1 (en) | 2010-06-14 | 2018-08-01 | The Scripps Research Institute | Reprogramming of cells to a new fate |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9716557D0 (en) * | 1997-08-06 | 1997-10-08 | Glaxo Group Ltd | Benzylidene-1,3-dihydro-indol-2-one derivatives having anti-cancer activity |
| GB9718913D0 (en) | 1997-09-05 | 1997-11-12 | Glaxo Group Ltd | Substituted oxindole derivatives |
| GB9904933D0 (en) | 1999-03-04 | 1999-04-28 | Glaxo Group Ltd | Compounds |
-
2001
- 2001-06-28 AU AU2001271611A patent/AU2001271611A1/en not_active Abandoned
- 2001-06-28 DE DE60106947T patent/DE60106947T2/de not_active Expired - Fee Related
- 2001-06-28 ES ES01950642T patent/ES2230337T3/es not_active Expired - Lifetime
- 2001-06-28 WO PCT/US2001/020703 patent/WO2002020524A1/en not_active Ceased
- 2001-06-28 AT AT01950642T patent/ATE281455T1/de not_active IP Right Cessation
- 2001-06-28 EP EP01950642A patent/EP1313732B1/en not_active Expired - Lifetime
- 2001-06-28 US US10/362,744 patent/US6720332B2/en not_active Expired - Fee Related
- 2001-06-28 JP JP2002525145A patent/JP2004508372A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002020524A1 (en) | 2002-03-14 |
| ES2230337T3 (es) | 2005-05-01 |
| AU2001271611A1 (en) | 2002-03-22 |
| JP2004508372A (ja) | 2004-03-18 |
| US6720332B2 (en) | 2004-04-13 |
| US20030195189A1 (en) | 2003-10-16 |
| EP1313732B1 (en) | 2004-11-03 |
| DE60106947D1 (de) | 2004-12-09 |
| EP1313732A1 (en) | 2003-05-28 |
| DE60106947T2 (de) | 2005-11-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |