ATE27696T1 - Naphthochinonderivate. - Google Patents

Naphthochinonderivate.

Info

Publication number
ATE27696T1
ATE27696T1 AT84104248T AT84104248T ATE27696T1 AT E27696 T1 ATE27696 T1 AT E27696T1 AT 84104248 T AT84104248 T AT 84104248T AT 84104248 T AT84104248 T AT 84104248T AT E27696 T1 ATE27696 T1 AT E27696T1
Authority
AT
Austria
Prior art keywords
naphthochinone
derivatives
alkyl
alkoxy
halogen
Prior art date
Application number
AT84104248T
Other languages
English (en)
Inventor
Alan Thomas Hudson
Anthony Winchester Randall
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Application granted granted Critical
Publication of ATE27696T1 publication Critical patent/ATE27696T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C62/30—Unsaturated compounds
    • C07C62/34—Unsaturated compounds containing ether groups, groups, groups, or groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00—Preparation of quinones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/26—Quinones containing groups having oxygen atoms singly bound to carbon atoms
    • C07C50/32—Quinones containing groups having oxygen atoms singly bound to carbon atoms the quinoid structure being part of a condensed ring system having two rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C61/08—Saturated compounds having a carboxyl group bound to a six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C61/15—Saturated compounds containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C61/16—Unsaturated compounds
    • C07C61/39—Unsaturated compounds containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C61/16—Unsaturated compounds
    • C07C61/40—Unsaturated compounds containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C62/08—Saturated compounds containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C62/08—Saturated compounds containing ether groups, groups, groups, or groups
    • C07C62/10—Saturated compounds containing ether groups, groups, groups, or groups with a six-membered ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT84104248T 1983-04-14 1984-04-14 Naphthochinonderivate. ATE27696T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB838310141A GB8310141D0 (en) 1983-04-14 1983-04-14 Naphthoquinone derivatives
EP84104248A EP0123238B1 (de) 1983-04-14 1984-04-14 Naphthochinonderivate

Publications (1)

Publication Number Publication Date
ATE27696T1 true ATE27696T1 (de) 1987-06-15

Family

ID=10541105

Family Applications (1)

Application Number Title Priority Date Filing Date
AT84104248T ATE27696T1 (de) 1983-04-14 1984-04-14 Naphthochinonderivate.

Country Status (17)

Country Link
EP (1) EP0123238B1 (de)
JP (1) JPS59205341A (de)
AT (1) ATE27696T1 (de)
AU (1) AU574353B2 (de)
CY (1) CY1549A (de)
DE (2) DE3464132D1 (de)
DK (1) DK172273B1 (de)
GB (1) GB8310141D0 (de)
HK (1) HK56690A (de)
IL (1) IL71545A (de)
LU (1) LU88579I2 (de)
MX (1) MX9202993A (de)
MY (1) MY102117A (de)
NL (1) NL950002I2 (de)
PH (1) PH22018A (de)
SG (1) SG39390G (de)
ZA (1) ZA842797B (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8310140D0 (en) * 1983-04-14 1983-05-18 Wellcome Found Antiprotozoal agents
US5175319A (en) * 1983-04-14 1992-12-29 Burroughs Wellcome Co. Naphthoquinone derivatives
EP0253501A3 (de) * 1986-07-16 1990-04-04 Imperial Chemical Industries Plc Als Fungizide verwendbare N-disubstituierte Cycloalkylmethylamine
DE3801743A1 (de) * 1987-07-03 1989-01-19 Bayer Ag Schaedlingsbekaempfungsmittel auf basis von substituierten 1,4-naphthochinonen und neue substituierte 1,4-naphthochinone
GB8819477D0 (en) * 1988-08-16 1988-09-21 Wellcome Found Medicaments
US5206268A (en) * 1988-08-16 1993-04-27 Burroughs Wellcome Co. Medicaments
US5225184A (en) * 1988-08-16 1993-07-06 Burroughs Wellcome Co. Medicaments
FI893835A (fi) * 1988-08-16 1990-02-17 Wellcome Found Laekemedel.
EP0567162A1 (de) * 1989-09-22 1993-10-27 The Wellcome Foundation Limited Heilmittel zur Behandlung von Toxoplasmose
GB8921516D0 (en) * 1989-09-22 1989-11-08 Wellcome Found Medicaments
GB8923254D0 (en) * 1989-10-16 1989-12-06 Wellcome Found Medicaments
GB9126874D0 (en) * 1991-12-18 1992-02-19 Wellcome Found Medicaments
GB9207517D0 (en) * 1992-04-06 1992-05-20 Wellcome Found Heterocyclic compounds
GB9216859D0 (en) * 1992-08-07 1992-09-23 Wellcome Found Medicaments
GB9224739D0 (en) * 1992-11-26 1993-01-13 Wellcome Found Medicaments
GB9226905D0 (en) * 1992-12-24 1993-02-17 Wellcome Found Pharmaceutical preparation
US5856362A (en) * 1994-09-02 1999-01-05 Glaxo Wellcome Inc. Medicaments for the treatment of toxoplasmosis
EA200700332A1 (ru) * 2004-07-16 2007-08-31 Юсв Лимитед Новые полиморфы атовахона и способ их получения
US20080254136A1 (en) * 2004-07-30 2008-10-16 Japan Health Sciences Foundation Antiprotozoal Agent
ITMI20070941A1 (it) * 2007-05-09 2008-11-10 Chimico Internazi0Nale S P A L Procedimento per la preparazione di naftochinoni trans2,3-disostituiti
CN101774901B (zh) * 2009-01-09 2012-10-03 武汉泰祥通生物技术有限公司 一种制备阿托伐醌的方法
US8987234B2 (en) 2009-08-20 2015-03-24 Ipca Laboratories Ltd. Complex for treatment and/or prophylaxis of parasitic infections
GB2476644B (en) 2009-12-23 2012-11-14 Haomamedica Ltd 1,4-Dihydro-1,4-dioxonaphtalene derivatives for the treatment of osteoporosis
JP2014510698A (ja) 2010-12-15 2014-05-01 グラクソ グループ リミテッド アトバコンの製造方法
EP2845588A1 (de) * 2013-09-09 2015-03-11 Centre National de la Recherche Scientifique (C.N.R.S.) PIN1-Hemmer zur Verwendung bei der Vorbeugung und/oder Behandlung von Theileriose sowie zugehörige Anwendungen

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2553647A (en) * 1946-03-20 1951-05-22 Research Corp Naphthoquinone antimalarials
EP0002228B1 (de) * 1977-11-22 1984-02-29 The Wellcome Foundation Limited Hydroxynaphtochinonderivate, ihre Präparate zur Behandlung und Verhütung von Theileriose bei Vieh und Schafen; Verfahren zu deren Herstellung; Naphtochinonderivate

Also Published As

Publication number Publication date
DK193584A (da) 1984-10-15
IL71545A (en) 1987-12-20
JPS59205341A (ja) 1984-11-20
MX9202993A (es) 1992-07-01
DE19475021I2 (de) 2001-08-02
IL71545A0 (en) 1984-07-31
GB8310141D0 (en) 1983-05-18
HK56690A (en) 1990-08-03
DK193584D0 (da) 1984-04-13
AU574353B2 (en) 1988-07-07
AU2679684A (en) 1984-10-18
LU88579I2 (fr) 1995-03-01
DK172273B1 (da) 1998-02-16
NL950002I1 (nl) 1995-03-01
PH22018A (en) 1988-05-13
EP0123238B1 (de) 1987-06-10
EP0123238A2 (de) 1984-10-31
MY102117A (en) 1992-03-31
EP0123238A3 (en) 1985-10-30
JPH0533212B2 (de) 1993-05-19
NL950002I2 (nl) 1998-04-01
CY1549A (en) 1991-03-22
SG39390G (en) 1990-11-23
DE3464132D1 (de) 1987-07-16
ZA842797B (en) 1985-11-27

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Legal Events

Date Code Title Description
EELA Cancelled due to lapse of time