ATE275573T1 - Neue nukleosid-analoge die polyzyklische aromatische gruppen als substituenten haben, verfahren zu ihrer herstellung und ihre anwendungen - Google Patents
Neue nukleosid-analoge die polyzyklische aromatische gruppen als substituenten haben, verfahren zu ihrer herstellung und ihre anwendungenInfo
- Publication number
- ATE275573T1 ATE275573T1 AT97925598T AT97925598T ATE275573T1 AT E275573 T1 ATE275573 T1 AT E275573T1 AT 97925598 T AT97925598 T AT 97925598T AT 97925598 T AT97925598 T AT 97925598T AT E275573 T1 ATE275573 T1 AT E275573T1
- Authority
- AT
- Austria
- Prior art keywords
- nucleic acids
- polycyclic aromatic
- nucleosides
- substituents
- applications
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 229940127073 nucleoside analogue Drugs 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 3
- 102000039446 nucleic acids Human genes 0.000 abstract 3
- 108020004707 nucleic acids Proteins 0.000 abstract 3
- 239000002777 nucleoside Substances 0.000 abstract 3
- 125000003835 nucleoside group Chemical group 0.000 abstract 3
- MWPLVEDNUUSJAV-UHFFFAOYSA-N anthracene Chemical compound C1=CC=CC2=CC3=CC=CC=C3C=C21 MWPLVEDNUUSJAV-UHFFFAOYSA-N 0.000 abstract 2
- 238000005859 coupling reaction Methods 0.000 abstract 2
- YNPNZTXNASCQKK-UHFFFAOYSA-N phenanthrene Chemical compound C1=CC=C2C3=CC=CC=C3C=CC2=C1 YNPNZTXNASCQKK-UHFFFAOYSA-N 0.000 abstract 2
- BBEAQIROQSPTKN-UHFFFAOYSA-N pyrene Chemical compound C1=CC=C2C=CC3=CC=CC4=CC=C1C2=C43 BBEAQIROQSPTKN-UHFFFAOYSA-N 0.000 abstract 2
- ASJSAQIRZKANQN-CRCLSJGQSA-N 2-deoxy-D-ribose Chemical compound OC[C@@H](O)[C@@H](O)CC=O ASJSAQIRZKANQN-CRCLSJGQSA-N 0.000 abstract 1
- PJANXHGTPQOBST-VAWYXSNFSA-N Stilbene Natural products C=1C=CC=CC=1/C=C/C1=CC=CC=C1 PJANXHGTPQOBST-VAWYXSNFSA-N 0.000 abstract 1
- XBDYBAVJXHJMNQ-UHFFFAOYSA-N Tetrahydroanthracene Natural products C1=CC=C2C=C(CCCC3)C3=CC2=C1 XBDYBAVJXHJMNQ-UHFFFAOYSA-N 0.000 abstract 1
- 150000001491 aromatic compounds Chemical class 0.000 abstract 1
- 238000006664 bond formation reaction Methods 0.000 abstract 1
- 230000008878 coupling Effects 0.000 abstract 1
- 238000010168 coupling process Methods 0.000 abstract 1
- 238000011067 equilibration Methods 0.000 abstract 1
- GVEPBJHOBDJJJI-UHFFFAOYSA-N fluoranthrene Natural products C1=CC(C2=CC=CC=C22)=C3C2=CC=CC3=C1 GVEPBJHOBDJJJI-UHFFFAOYSA-N 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
- SLIUAWYAILUBJU-UHFFFAOYSA-N pentacene Chemical compound C1=CC=CC2=CC3=CC4=CC5=CC=CC=C5C=C4C=C3C=C21 SLIUAWYAILUBJU-UHFFFAOYSA-N 0.000 abstract 1
- 125000005575 polycyclic aromatic hydrocarbon group Chemical group 0.000 abstract 1
- 239000000523 sample Substances 0.000 abstract 1
- PJANXHGTPQOBST-UHFFFAOYSA-N stilbene Chemical compound C=1C=CC=CC=1C=CC1=CC=CC=C1 PJANXHGTPQOBST-UHFFFAOYSA-N 0.000 abstract 1
- 235000021286 stilbenes Nutrition 0.000 abstract 1
- IFLREYGFSNHWGE-UHFFFAOYSA-N tetracene Chemical compound C1=CC=CC2=CC3=CC4=CC=CC=C4C=C3C=C21 IFLREYGFSNHWGE-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
- C07H7/04—Carbocyclic radicals
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Saccharide Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1777296P | 1996-05-15 | 1996-05-15 | |
| PCT/US1997/008307 WO1997043298A1 (en) | 1996-05-15 | 1997-05-15 | Novel nucleoside analogs with polycyclic aromatic groups attached, methods of synthesis and uses therefor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE275573T1 true ATE275573T1 (de) | 2004-09-15 |
Family
ID=21784456
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97925598T ATE275573T1 (de) | 1996-05-15 | 1997-05-15 | Neue nukleosid-analoge die polyzyklische aromatische gruppen als substituenten haben, verfahren zu ihrer herstellung und ihre anwendungen |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0927188B1 (de) |
| JP (1) | JP2000511160A (de) |
| AT (1) | ATE275573T1 (de) |
| CA (1) | CA2253654C (de) |
| DE (1) | DE69730609D1 (de) |
| WO (1) | WO1997043298A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7135312B2 (en) | 1993-04-15 | 2006-11-14 | University Of Rochester | Circular DNA vectors for synthesis of RNA and DNA |
| US7033753B1 (en) | 1999-01-15 | 2006-04-25 | University Of Rochester | Compositions and methods for nonenzymatic ligation of oligonucleotides and detection of genetic polymorphisms |
| US6479650B1 (en) * | 1999-12-14 | 2002-11-12 | Research Corporation Technologies, Inc. | Fluorescent nucleoside analogs and combinatorial fluorophore arrays comprising same |
| EP2292626B1 (de) | 2000-08-04 | 2014-05-21 | Senseonics, Incorporated | Nachweis von Analyten in wässrigen Medien |
| CN1653079B (zh) * | 2001-12-18 | 2010-06-16 | 人类遗传标记控股有限公司 | 包括嵌入剂的假核苷酸 |
| JP2004175708A (ja) * | 2002-11-26 | 2004-06-24 | Geneticlab Co Ltd | 二環性ナフチリジンヌクレオシド |
| US7935836B2 (en) | 2004-05-18 | 2011-05-03 | Alexander Graham Fallis | Compounds comprising a linear series of five fused carbon rings, and preparation thereof |
| US7655809B2 (en) | 2004-05-18 | 2010-02-02 | University Of Ottawa | Compounds comprising a linear series of five fused carbon rings, and preparation thereof |
| WO2018013999A1 (en) | 2016-07-15 | 2018-01-18 | Am Chemicals Llc | Non-nucleosidic solid supports and phosphoramidite building blocks for oligonucleotide synthesis |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH09505556A (ja) * | 1993-08-18 | 1997-06-03 | クロマジェン インク | 蛍光性ｎ−ヌクレオシド及び蛍光性ｎ−ヌクレオシド構造類似体の応用 |
-
1997
- 1997-05-15 JP JP09541138A patent/JP2000511160A/ja not_active Ceased
- 1997-05-15 AT AT97925598T patent/ATE275573T1/de not_active IP Right Cessation
- 1997-05-15 WO PCT/US1997/008307 patent/WO1997043298A1/en not_active Ceased
- 1997-05-15 CA CA002253654A patent/CA2253654C/en not_active Expired - Fee Related
- 1997-05-15 DE DE69730609T patent/DE69730609D1/de not_active Expired - Lifetime
- 1997-05-15 EP EP97925598A patent/EP0927188B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2253654A1 (en) | 1997-11-20 |
| EP0927188A1 (de) | 1999-07-07 |
| JP2000511160A (ja) | 2000-08-29 |
| CA2253654C (en) | 2003-01-28 |
| EP0927188B1 (de) | 2004-09-08 |
| WO1997043298A1 (en) | 1997-11-20 |
| DE69730609D1 (de) | 2004-10-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |