ATE272636T1 - Naphthyridine die den rezeptor il-4 und den faktor g-csf beeinflussen - Google Patents

Naphthyridine die den rezeptor il-4 und den faktor g-csf beeinflussen

Info

Publication number
ATE272636T1
ATE272636T1 AT97932142T AT97932142T ATE272636T1 AT E272636 T1 ATE272636 T1 AT E272636T1 AT 97932142 T AT97932142 T AT 97932142T AT 97932142 T AT97932142 T AT 97932142T AT E272636 T1 ATE272636 T1 AT E272636T1
Authority
AT
Austria
Prior art keywords
naphthyridines
receptor
affect
csf factor
compounds
Prior art date
Application number
AT97932142T
Other languages
English (en)
Inventor
Daniel M Solomon
Michael J Grace
Jay S Fine
Loretta A Bober
Margaret H Sherlock
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of ATE272636T1 publication Critical patent/ATE272636T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT97932142T 1996-06-20 1997-06-18 Naphthyridine die den rezeptor il-4 und den faktor g-csf beeinflussen ATE272636T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US66918596A 1996-06-20 1996-06-20
PCT/US1997/009202 WO1997048368A2 (en) 1996-06-20 1997-06-18 Naphthyridines which affect il-4 and g-csf

Publications (1)

Publication Number Publication Date
ATE272636T1 true ATE272636T1 (de) 2004-08-15

Family

ID=24685412

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97932142T ATE272636T1 (de) 1996-06-20 1997-06-18 Naphthyridine die den rezeptor il-4 und den faktor g-csf beeinflussen

Country Status (9)

Country Link
EP (1) EP0912571B1 (de)
JP (2) JP4181220B2 (de)
CN (1) CN1228090A (de)
AT (1) ATE272636T1 (de)
AU (1) AU3567397A (de)
CA (1) CA2258752C (de)
DE (1) DE69730137T2 (de)
ES (1) ES2225980T3 (de)
WO (1) WO1997048368A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2258752C (en) * 1996-06-20 2006-08-15 Schering Corporation Naphthyridines which affect il-4 and g-csf
KR20010102000A (ko) 1999-02-08 2001-11-15 윌리암스 로저 에이 술파마토 히드록삼산 메탈로프로테아제 억제제
US6800646B1 (en) 1999-02-08 2004-10-05 Pharmacia Corporation Sulfamato hydroxamic acid metalloprotease inhibitor
NZ525439A (en) * 2000-09-29 2004-11-26 Topotarget Uk Ltd Carbamic acid compounds comprising a sulfonamide linkage as HDAC inhibitors
EP1430894A4 (de) * 2001-09-05 2007-12-12 Eisai R&D Man Co Ltd Lymphozyten-aktivierungshemmer und mittel zur behandlung von autoimmunkrankheiten
MXPA04010555A (es) 2002-04-25 2005-02-17 Pharmacia Corp Acidos piperidinil- y piperazinil-sulfonilmetil hidroxamicos y su uso como inhibidores de proteasa.
RU2007113915A (ru) * 2004-09-14 2008-10-27 Новартис АГ (CH) Способ получения 6, 8-замещенных производных 1, 7-нафтиридина реакцией производного 8-галоген-1, 7-нафтиридина с органическими производными борной кислоты и промежуточные соединения для этого способа
DE102008019838A1 (de) * 2008-04-19 2009-12-10 Boehringer Ingelheim International Gmbh Neue Arylsulfonylglycin-Derivate, deren Herstellung und deren Verwendung als Arzneimittel

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2550575A1 (de) * 1975-11-11 1977-05-12 Scherico Ltd Naphthyridine, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
GB1545767A (en) * 1976-06-30 1979-05-16 Aspro Nicholas Ltd Isoquinoline derivatives
US4942163A (en) * 1989-03-07 1990-07-17 E. I. Du Pont De Nemours And Company 1(2H)-isoquinolinones and 1-isoquinolineamines as cancer chemotherapeutic agents
CA2258752C (en) * 1996-06-20 2006-08-15 Schering Corporation Naphthyridines which affect il-4 and g-csf

Also Published As

Publication number Publication date
CN1228090A (zh) 1999-09-08
DE69730137T2 (de) 2005-07-14
DE69730137D1 (de) 2004-09-09
WO1997048368A2 (en) 1997-12-24
EP0912571B1 (de) 2004-08-04
JP2002501472A (ja) 2002-01-15
EP0912571A2 (de) 1999-05-06
CA2258752C (en) 2006-08-15
WO1997048368A3 (en) 1998-02-05
CA2258752A1 (en) 1997-12-24
AU3567397A (en) 1998-01-07
JP4181220B2 (ja) 2008-11-12
ES2225980T3 (es) 2005-03-16
JP2008255119A (ja) 2008-10-23

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties