ATE270286T1 - Macrozyklische laktone, zusammensetzungen und verfahren zur verwendung - Google Patents

Macrozyklische laktone, zusammensetzungen und verfahren zur verwendung

Info

Publication number
ATE270286T1
ATE270286T1 AT98935844T AT98935844T ATE270286T1 AT E270286 T1 ATE270286 T1 AT E270286T1 AT 98935844 T AT98935844 T AT 98935844T AT 98935844 T AT98935844 T AT 98935844T AT E270286 T1 ATE270286 T1 AT E270286T1
Authority
AT
Austria
Prior art keywords
chain
alkyl
present
compound
aryl
Prior art date
Application number
AT98935844T
Other languages
English (en)
Inventor
Michael R Boyd
Tawnya C Mckee
John H Ii Cardellina
John A Beutler
Karen Erickson
Deborah Galinis
Lewis Pannell
Original Assignee
Us Gov Health & Human Serv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Gov Health & Human Serv filed Critical Us Gov Health & Human Serv
Application granted granted Critical
Publication of ATE270286T1 publication Critical patent/ATE270286T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D321/00—Heterocyclic compounds containing rings having two oxygen atoms as the only ring hetero atoms, not provided for by groups C07D317/00 - C07D319/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Pyrane Compounds (AREA)
AT98935844T 1997-07-25 1998-07-23 Macrozyklische laktone, zusammensetzungen und verfahren zur verwendung ATE270286T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5378497P 1997-07-25 1997-07-25
PCT/US1998/015011 WO1999005136A1 (en) 1997-07-25 1998-07-23 Macrocyclic lactones, compositions, and methods of use

Publications (1)

Publication Number Publication Date
ATE270286T1 true ATE270286T1 (de) 2004-07-15

Family

ID=21986519

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98935844T ATE270286T1 (de) 1997-07-25 1998-07-23 Macrozyklische laktone, zusammensetzungen und verfahren zur verwendung

Country Status (8)

Country Link
US (1) US6353019B1 (de)
EP (1) EP1000053B1 (de)
JP (1) JP2001510838A (de)
AT (1) ATE270286T1 (de)
AU (1) AU740668B2 (de)
CA (1) CA2297198C (de)
DE (1) DE69824855T2 (de)
WO (1) WO1999005136A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7381744B1 (en) * 1999-03-05 2008-06-03 The United States Of America As Represented By The Department Of Health And Human Services Method of treating osteoporosis comprising vacuolar-type (H+)-ATPase-inhibiting compounds
JP4980542B2 (ja) 2000-07-24 2012-07-18 アメリカ合衆国 生物活性マクロライド、組成物、及びそれらの使用
US6734209B2 (en) 2001-08-03 2004-05-11 Board Of Regents The University Of Texas System Synthetic salicylihalamides, apicularens and derivatives thereof
US6617348B1 (en) 2000-08-04 2003-09-09 Ut Southwestern Medical Center Synthetic salicylihalamides, apicularens and derivatives thereof
EP1944307A3 (de) 2000-08-04 2008-07-30 Board of Regents, The University of Texas System Synthetische Salicylihalamide, Apicularene und Derivate davon
US20030064542A1 (en) * 2001-10-02 2003-04-03 Corisis David J. Methods of packaging an integrated circuit
TW200524892A (en) * 2003-09-24 2005-08-01 Glaxo Group Ltd Calcilytic compounds
ES2659818T3 (es) * 2013-11-28 2018-03-19 Universiteit Gent Análogos de pelorusido

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU202248B (en) 1988-06-14 1991-02-28 Chinoin Gyogyszer Es Vegyeszet Process for producing pseudo-primicin, it's components and pharmaceutical compositions containing them as active components
US5430053A (en) * 1994-04-19 1995-07-04 Arizona Board Of Regents Acting On Behalf Of Arizona State University Isolation and structure of dictyostatin 1
US6207826B1 (en) * 1995-03-27 2001-03-27 Isis Pharmaceuticals, Inc. Macrocyclic compounds having nitrogen-containing linkages
EP0823429B1 (de) * 1995-04-26 2000-07-12 Kyowa Hakko Kogyo Co., Ltd. Derivate des radicicols
US6124453A (en) * 1995-07-04 2000-09-26 Novartis Ag Macrolides
US6441186B1 (en) 1996-12-13 2002-08-27 The Scripps Research Institute Epothilone analogs
JPH11180984A (ja) * 1997-12-22 1999-07-06 Kyowa Hakko Kogyo Co Ltd クロラクトマイシン化合物
US6121257A (en) * 1999-03-31 2000-09-19 Abbott Laboratories Sulfamate containing macrocyclic immunomodulators

Also Published As

Publication number Publication date
CA2297198C (en) 2010-06-22
DE69824855D1 (de) 2004-08-05
DE69824855T2 (de) 2005-08-25
EP1000053B1 (de) 2004-06-30
EP1000053A1 (de) 2000-05-17
JP2001510838A (ja) 2001-08-07
US6353019B1 (en) 2002-03-05
CA2297198A1 (en) 1999-02-04
AU8501598A (en) 1999-02-16
AU740668B2 (en) 2001-11-08
WO1999005136A1 (en) 1999-02-04

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