ATE267019T1 - Methoden zur inhibition von hiv-assotiierte krankheit mittels monoklonaler antikörper gegen sich selbstgerichtete zytotoxische t-zellen - Google Patents

Methoden zur inhibition von hiv-assotiierte krankheit mittels monoklonaler antikörper gegen sich selbstgerichtete zytotoxische t-zellen

Info

Publication number
ATE267019T1
ATE267019T1 AT94912826T AT94912826T ATE267019T1 AT E267019 T1 ATE267019 T1 AT E267019T1 AT 94912826 T AT94912826 T AT 94912826T AT 94912826 T AT94912826 T AT 94912826T AT E267019 T1 ATE267019 T1 AT E267019T1
Authority
AT
Austria
Prior art keywords
hiv
monoclonal antibodies
inhibition
cells
methods
Prior art date
Application number
AT94912826T
Other languages
English (en)
Inventor
D Allen Allen
Original Assignee
D Allen Allen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by D Allen Allen filed Critical D Allen Allen
Application granted granted Critical
Publication of ATE267019T1 publication Critical patent/ATE267019T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2815—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD8
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2821—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against ICAM molecules, e.g. CD50, CD54, CD102
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2833—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against MHC-molecules, e.g. HLA-molecules
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2845—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta2-subunit-containing molecules, e.g. CD11, CD18
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • AIDS & HIV (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT94912826T 1993-03-19 1994-03-21 Methoden zur inhibition von hiv-assotiierte krankheit mittels monoklonaler antikörper gegen sich selbstgerichtete zytotoxische t-zellen ATE267019T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US3340593A 1993-03-19 1993-03-19
US16575193A 1993-12-13 1993-12-13
PCT/US1994/003055 WO1994021295A1 (en) 1993-03-19 1994-03-21 Methods for inhibiting hiv associated disease using monoclonal antibodies directed against anti-self cytotoxic t-cells
CA002425086A CA2425086A1 (en) 1993-03-19 2003-04-10 Method of increasing the delayed-type hypersensitivity response by infusing lfa-1 specific antibodies

Publications (1)

Publication Number Publication Date
ATE267019T1 true ATE267019T1 (de) 2004-06-15

Family

ID=34084057

Family Applications (2)

Application Number Title Priority Date Filing Date
AT04101437T ATE408418T1 (de) 1993-03-19 1994-03-21 Methoden zur inhibition von hiv-assoziierten krankheiten mittels monoklonaler antikörper gegen sich selbstgerichtete zytotoxische t-zellen
AT94912826T ATE267019T1 (de) 1993-03-19 1994-03-21 Methoden zur inhibition von hiv-assotiierte krankheit mittels monoklonaler antikörper gegen sich selbstgerichtete zytotoxische t-zellen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT04101437T ATE408418T1 (de) 1993-03-19 1994-03-21 Methoden zur inhibition von hiv-assoziierten krankheiten mittels monoklonaler antikörper gegen sich selbstgerichtete zytotoxische t-zellen

Country Status (10)

Country Link
US (1) US5424066A (de)
EP (2) EP1438970B1 (de)
AT (2) ATE408418T1 (de)
AU (1) AU684074B2 (de)
CA (2) CA2156495C (de)
DE (2) DE69435142D1 (de)
DK (1) DK1438970T3 (de)
ES (2) ES2219647T3 (de)
PT (2) PT690725E (de)
WO (1) WO1994021295A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6534057B2 (en) 1993-03-19 2003-03-18 Allen D. Allen Method increasing the delayed-type hypersensitivity response by infusing LFA-1-specific antibodies
US5651970A (en) * 1993-03-19 1997-07-29 Allen; Allen D. Method for inhibiting disease associated with the human immunodeficiency virus through the use of monoclonal antibodies directed against anti-self cytotoxic T-lymphocytes or their lytics
WO1995028176A1 (en) * 1994-04-15 1995-10-26 Allen Allen D Method of treating hiv infection using antibodies against cytotoxic t-cells and thymic humoral factor
CA2191333C (en) * 1995-04-14 2006-08-01 Hirofumi Moriyama Phosphor with afterglow characteristic
AU6256796A (en) * 1995-06-06 1996-12-24 D. Allen Allen Method for treating molluscum contagiosum resulting from hiv infection
WO1996040215A1 (en) * 1995-06-07 1996-12-19 Connective Therapeutics, Inc. Treating immune deficiency diseases using t cell receptor peptides
JP2001511187A (ja) * 1997-02-28 2001-08-07 エンゾー セラピュウティクス， インコーポレイテッド 選択的免疫ダウンレギュレーション（ｓｉｄｒ）を行う新規プロセス
US20030170258A1 (en) * 2001-05-09 2003-09-11 Enzo Therapeutics, Inc. Novel processes implementing selective immune down regulation (SIDR)
US6919077B2 (en) * 2002-09-27 2005-07-19 Aids Research, Llc LFA-1 alpha subunit antibodies and methods of use

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5002869A (en) * 1987-11-02 1991-03-26 Dana-Farber Cancer Institute Monoclonal antibody specific to a novel epitope of the LFA-1 antigen of human T lymphocytes

Also Published As

Publication number Publication date
ES2219647T3 (es) 2004-12-01
WO1994021295A1 (en) 1994-09-29
US5424066A (en) 1995-06-13
DE69435142D1 (de) 2008-10-30
CA2425086A1 (en) 2004-10-10
EP1438970B1 (de) 2008-09-17
DE69433789T2 (de) 2005-06-23
CA2156495C (en) 2008-11-18
PT1438970E (pt) 2008-12-26
EP0690725B1 (de) 2004-05-19
EP0690725A1 (de) 1996-01-10
ES2314341T3 (es) 2009-03-16
DK1438970T3 (da) 2008-12-15
EP0690725A4 (de) 1997-09-03
AU6522194A (en) 1994-10-11
EP1438970A3 (de) 2004-12-08
DE69433789D1 (de) 2004-06-24
PT690725E (pt) 2004-10-29
ATE408418T1 (de) 2008-10-15
EP1438970A2 (de) 2004-07-21
AU684074B2 (en) 1997-12-04
HK1067958A1 (en) 2005-04-22
CA2156495A1 (en) 1994-09-29

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