ATE263373T1 - Verfahren und zusammensetzungen zum screenen von modulatoren von sphingosinkinasen - Google Patents
Verfahren und zusammensetzungen zum screenen von modulatoren von sphingosinkinasenInfo
- Publication number
- ATE263373T1 ATE263373T1 AT01402500T AT01402500T ATE263373T1 AT E263373 T1 ATE263373 T1 AT E263373T1 AT 01402500 T AT01402500 T AT 01402500T AT 01402500 T AT01402500 T AT 01402500T AT E263373 T1 ATE263373 T1 AT E263373T1
- Authority
- AT
- Austria
- Prior art keywords
- methods
- compositions
- kinases
- sphingosine kinases
- screening modulators
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/60—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances involving radioactive labelled substances
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/91—Transferases (2.)
- G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- G01N2333/91205—Phosphotransferases in general
- G01N2333/9121—Phosphotransferases in general with an alcohol group as acceptor (2.7.1), e.g. general tyrosine, serine or threonine kinases
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Endocrinology (AREA)
- General Engineering & Computer Science (AREA)
- Obesity (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP00402684A EP1195604A1 (de) | 2000-09-29 | 2000-09-29 | Verfahren und Zusammensetzungen zum Screenen von Modulatoren von Lipidkinasen |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE263373T1 true ATE263373T1 (de) | 2004-04-15 |
Family
ID=8173885
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT01402500T ATE263373T1 (de) | 2000-09-29 | 2001-09-28 | Verfahren und zusammensetzungen zum screenen von modulatoren von sphingosinkinasen |
Country Status (12)
Country | Link |
---|---|
US (1) | US6723525B2 (de) |
EP (2) | EP1195604A1 (de) |
JP (1) | JP2004509638A (de) |
AT (1) | ATE263373T1 (de) |
AU (1) | AU2001289939A1 (de) |
CA (1) | CA2423889A1 (de) |
DE (1) | DE60102539T2 (de) |
DK (1) | DK1195605T3 (de) |
ES (1) | ES2218351T3 (de) |
PT (1) | PT1195605E (de) |
TR (1) | TR200400941T4 (de) |
WO (1) | WO2002027318A1 (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6649362B2 (en) * | 1997-09-08 | 2003-11-18 | Medvet Science Pty. Ltd. | Screening method for an agent having an effect on a sphingosine kinase signaling pathway |
US8945932B2 (en) | 2004-07-06 | 2015-02-03 | Perkinelmer Health Sciences, Inc. | Methods and compositions for detecting and isolating phosphorylated molecules using hydrated metal oxides |
US20060270631A1 (en) * | 2005-05-26 | 2006-11-30 | Smith Charles D | Methods for the treatment and prevention of angiogenic diseases |
EP1913390B1 (de) * | 2005-08-11 | 2012-05-30 | PerkinElmer LAS, Inc. | Testverfahren unter Verwendung von partikelförmigen Hohlkörpern und diese enthaltende Kits |
DE602006012072D1 (de) * | 2005-10-12 | 2010-03-18 | Allergan Inc | Tests der molekularen oder subzellulären interaktivität unter verwendung von depolarisierung nach resonanzenergietransfer (daret) |
EP2586874B1 (de) * | 2010-06-28 | 2015-04-22 | Daiichi Sankyo Company, Limited | Verfahren zum screening auf s1p-lyase-hemmer mit kultivierten zellen |
EP2727926A4 (de) | 2011-06-28 | 2015-03-04 | Daiichi Sankyo Co Ltd | Phosphorsäure-ester-derivat |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4568649A (en) | 1983-02-22 | 1986-02-04 | Immunex Corporation | Immediate ligand detection assay |
EP0154734B1 (de) | 1984-03-15 | 1990-08-29 | Immunex Corporation | Test zur sofortigen Feststellung von Liganden, Testsatz und seine Herstellung |
CA2007507C (en) * | 1989-02-03 | 1998-05-19 | Yasuyuki Igarashi | Sphingosine and n-methyl-sphingosine as inhibitor of cell growth |
EP0502123A4 (en) * | 1989-12-01 | 1992-11-04 | Packard Instrument Company, Inc. | Scintillation proximity radioimmunoassay using solid scintillator support body |
US5677189A (en) * | 1995-06-29 | 1997-10-14 | Oncomembrane, Inc. | Method for quantifying sphingosine and for diagnosing platelet activation |
AUPO900297A0 (en) * | 1997-09-08 | 1997-10-02 | Medvet Science Pty. Ltd. | A method of modulating cellular activity |
US6098631A (en) * | 1998-01-21 | 2000-08-08 | The Regents Of The University Of Michigan | Compositions and methods for treating autoimmune disease |
CA2329124A1 (en) * | 1998-05-26 | 1999-12-02 | Office Of The Dean Of Research And Graduate Education | Sphingosine kinase, cloning, expression and methods of use |
ATE409486T1 (de) * | 1998-06-29 | 2008-10-15 | Children S Hospital Los Angele | Behandlung hyperproliferativer erkrankungen |
GB9828375D0 (en) * | 1998-12-22 | 1999-02-17 | Janssen Pharmaceutica Nv | Human akt-3 |
-
2000
- 2000-09-29 EP EP00402684A patent/EP1195604A1/de not_active Withdrawn
-
2001
- 2001-09-28 AU AU2001289939A patent/AU2001289939A1/en not_active Abandoned
- 2001-09-28 JP JP2002530646A patent/JP2004509638A/ja active Pending
- 2001-09-28 DE DE60102539T patent/DE60102539T2/de not_active Expired - Fee Related
- 2001-09-28 DK DK01402500T patent/DK1195605T3/da active
- 2001-09-28 US US09/964,860 patent/US6723525B2/en not_active Expired - Fee Related
- 2001-09-28 AT AT01402500T patent/ATE263373T1/de not_active IP Right Cessation
- 2001-09-28 EP EP01402500A patent/EP1195605B1/de not_active Expired - Lifetime
- 2001-09-28 PT PT01402500T patent/PT1195605E/pt unknown
- 2001-09-28 WO PCT/EP2001/011250 patent/WO2002027318A1/en active Application Filing
- 2001-09-28 CA CA002423889A patent/CA2423889A1/en not_active Abandoned
- 2001-09-28 TR TR2004/00941T patent/TR200400941T4/ unknown
- 2001-09-28 ES ES01402500T patent/ES2218351T3/es not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP1195605B1 (de) | 2004-03-31 |
AU2001289939A1 (en) | 2002-04-08 |
EP1195605A1 (de) | 2002-04-10 |
US20020042091A1 (en) | 2002-04-11 |
ES2218351T3 (es) | 2004-11-16 |
TR200400941T4 (tr) | 2004-06-21 |
DE60102539T2 (de) | 2005-04-07 |
DK1195605T3 (da) | 2004-08-02 |
EP1195604A1 (de) | 2002-04-10 |
CA2423889A1 (en) | 2002-04-04 |
JP2004509638A (ja) | 2004-04-02 |
PT1195605E (pt) | 2004-08-31 |
DE60102539D1 (de) | 2004-05-06 |
WO2002027318A1 (en) | 2002-04-04 |
US6723525B2 (en) | 2004-04-20 |
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Legal Events
Date | Code | Title | Description |
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UEP | Publication of translation of european patent specification |
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REN | Ceased due to non-payment of the annual fee |