ATE260076T1 - Nierenprothese - Google Patents

Nierenprothese

Info

Publication number
ATE260076T1
ATE260076T1 AT97941403T AT97941403T ATE260076T1 AT E260076 T1 ATE260076 T1 AT E260076T1 AT 97941403 T AT97941403 T AT 97941403T AT 97941403 T AT97941403 T AT 97941403T AT E260076 T1 ATE260076 T1 AT E260076T1
Authority
AT
Austria
Prior art keywords
kidney
analogs
prosthetic
nephron
prepared
Prior art date
Application number
AT97941403T
Other languages
German (de)
English (en)
Inventor
Anthony Atala
James J Yoo
Samy Ashkar
Original Assignee
Childrens Medical Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Childrens Medical Center filed Critical Childrens Medical Center
Application granted granted Critical
Publication of ATE260076T1 publication Critical patent/ATE260076T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0684—Cells of the urinary tract or kidneys
    • C12N5/0686—Kidney cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/26—Materials or treatment for tissue regeneration for kidney reconstruction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/20—Transition metals
    • C12N2500/24—Iron; Fe chelators; Transferrin
    • C12N2500/25—Insulin-transferrin; Insulin-transferrin-selenium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/01—Modulators of cAMP or cGMP, e.g. non-hydrolysable analogs, phosphodiesterase inhibitors, cholera toxin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/39—Steroid hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cell Biology (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Vascular Medicine (AREA)
  • Microbiology (AREA)
  • Dispersion Chemistry (AREA)
  • External Artificial Organs (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Prostheses (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT97941403T 1996-09-05 1997-09-04 Nierenprothese ATE260076T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2551196P 1996-09-05 1996-09-05
PCT/US1997/015470 WO1998009582A1 (en) 1996-09-05 1997-09-04 Prosthetic kidney and its use for treating kidney disease

Publications (1)

Publication Number Publication Date
ATE260076T1 true ATE260076T1 (de) 2004-03-15

Family

ID=21826516

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97941403T ATE260076T1 (de) 1996-09-05 1997-09-04 Nierenprothese

Country Status (6)

Country Link
EP (1) EP0929271B1 (enExample)
JP (1) JP4023828B2 (enExample)
AT (1) ATE260076T1 (enExample)
AU (1) AU4331897A (enExample)
DE (1) DE69727817T2 (enExample)
WO (1) WO1998009582A1 (enExample)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2307567C (en) 1997-10-31 2009-01-20 Children's Medical Center Corporation Polymer matrix/cell construct for bladder reconstruction
US6368859B1 (en) 1999-12-29 2002-04-09 Children's Medical Center Corporation Methods and compositions for producing a fascial sling
US6428802B1 (en) 1999-12-29 2002-08-06 Children's Medical Center Corp. Preparing artificial organs by forming polylayers of different cell populations on a substrate
US6479064B1 (en) 1999-12-29 2002-11-12 Children's Medical Center Corporation Culturing different cell populations on a decellularized natural biostructure for organ reconstruction
AT411328B (de) * 2000-07-12 2003-12-29 Universitaetsklinikum Freiburg Röhrensystem zur rekonstruktion einer harnröhre
KR100864648B1 (ko) * 2001-05-17 2008-10-23 가부시키가이샤 가네카 단백질 대사 기능을 갖는 인공 신장 및 그 제작 방법
WO2003013588A1 (en) * 2001-08-08 2003-02-20 Kaken Pharmaceutical Co., Ltd. Kidney regeneration material comprising cells and cell growth factor
EP1446171A1 (en) * 2001-11-16 2004-08-18 Children's Medical Center Corporation Augmentation of organ function
AU2007201136B2 (en) * 2001-11-16 2011-03-03 Children's Medical Center Corporation Augmentation of organ function
DE602004022508D1 (de) 2003-01-16 2009-09-24 Gen Hospital Corp Verwendung von dreidimensionalen, mikrogefertigten, mittels gewebetechnologie hergestellten systemen für pharmakologische anwendungen
US8092549B2 (en) * 2004-09-24 2012-01-10 The Invention Science Fund I, Llc Ciliated stent-like-system
US8353896B2 (en) 2004-04-19 2013-01-15 The Invention Science Fund I, Llc Controllable release nasal system
US9801527B2 (en) 2004-04-19 2017-10-31 Gearbox, Llc Lumen-traveling biological interface device
US8337482B2 (en) 2004-04-19 2012-12-25 The Invention Science Fund I, Llc System for perfusion management
US7998060B2 (en) 2004-04-19 2011-08-16 The Invention Science Fund I, Llc Lumen-traveling delivery device
US8361013B2 (en) 2004-04-19 2013-01-29 The Invention Science Fund I, Llc Telescoping perfusion management system
US8000784B2 (en) 2004-04-19 2011-08-16 The Invention Science Fund I, Llc Lumen-traveling device
US8024036B2 (en) 2007-03-19 2011-09-20 The Invention Science Fund I, Llc Lumen-traveling biological interface device and method of use
US9011329B2 (en) 2004-04-19 2015-04-21 Searete Llc Lumenally-active device
US20120035438A1 (en) 2006-04-12 2012-02-09 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Path selection by a lumen traveling device in a body tub tree based on previous path
US20090209019A1 (en) * 2006-10-17 2009-08-20 Tokai University Educational System Bioartificial Renal Tubule
US9580688B2 (en) 2007-06-08 2017-02-28 Wake Forest University Health Sciences Kidney structures and methods of forming the same
EP2162529B1 (en) 2007-06-08 2019-03-27 Wake Forest University Health Sciences Selective cell therapy for the treatment of renal failure
JP5974233B2 (ja) * 2008-11-12 2016-08-24 リージェンメド（ケイマン）エルティーディー． 単離した腎細胞およびその使用
WO2010057013A1 (en) 2008-11-14 2010-05-20 Wake Forest University Health Sciences Selective cell therapy for the treatment of renal failure
KR101227453B1 (ko) * 2010-07-29 2013-01-29 서강대학교산학협력단 인공 신단위 장치
MA40495A (fr) * 2014-10-06 2016-04-14 Organovo Inc Tissus rénaux produits par génie génétique, réseaux correspondants, et procédés de production
EP3291851B1 (en) * 2015-05-05 2021-03-03 President and Fellows of Harvard College Tubular tissue construct and a method of printing
US20190232232A1 (en) 2016-07-14 2019-08-01 Qidni Labs, Inc. Biocompatible and hemocompatible material and filter
JP2019537729A (ja) 2016-09-28 2019-12-26 オルガノボ インコーポレイテッド アッセイにおける人工腎臓組織の使用
CA3062611A1 (en) * 2017-05-14 2018-11-22 Paragate Medical Ltd. Implantable fluid extraction system
US10822461B2 (en) 2017-10-05 2020-11-03 Fresenius Medical Care Holdings, Inc. Polysulfone-urethane copolymer, membranes and products incorporating same, and methods for making and using same
WO2020178420A1 (en) * 2019-03-06 2020-09-10 Gambro Lundia Ab Blood treatment device comprising alkaline phosphatase
CN120168756A (zh) * 2025-03-10 2025-06-20 中国人民解放军总医院第一医学中心 一种智能化的生物肾透析治疗装置

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5266480A (en) * 1986-04-18 1993-11-30 Advanced Tissue Sciences, Inc. Three-dimensional skin culture system
US4769037A (en) * 1986-10-28 1988-09-06 Midcalf Robert J Artificial replacement kidney implant and method of dialyzing blood
WO1993007913A1 (en) * 1991-10-24 1993-04-29 Children's Medical Center Corporation Neomorphogenesis of urological structures in vivo from cell culture
US5549674A (en) * 1992-03-02 1996-08-27 The Regents Of The University Of Michigan Methods and compositions of a bioartificial kidney suitable for use in vivo or ex vivo
US5429938A (en) * 1992-03-02 1995-07-04 University Of Michigan Methods and compositions for isolation and growth of kidney tubule stem cells, in vitro kidney tubulogenesis and ex vivo construction of renal tubules

Also Published As

Publication number Publication date
AU4331897A (en) 1998-03-26
DE69727817T2 (de) 2005-01-05
EP0929271A1 (en) 1999-07-21
DE69727817D1 (de) 2004-04-01
EP0929271B1 (en) 2004-02-25
JP2001506871A (ja) 2001-05-29
WO1998009582A1 (en) 1998-03-12
JP4023828B2 (ja) 2007-12-19

Similar Documents

Publication Publication Date Title
ATE260076T1 (de) Nierenprothese
ES2160116T3 (es) Modelo de equivalente de cornea producido in vitro.
WO1995011048A3 (en) METHODS AND COMPOSITIONS OF A BIOARTIFICIAL KIDNEY SUITABLE FOR USE IN VIVO OR $i(EX VIVO)
ATE231181T1 (de) Bioreaktor
DE59912281D1 (de) Biohybrider Gelenkflächenersatz
ATE384782T1 (de) Rekonstruktion von organen aus einem dezellularisierten biologischem gerüst
DK0991402T3 (da) Fremgangsmåde til fremstilling af en poly(vinylalkohol)cryogel
DE69408153D1 (de) Wasserentzug bei hydrogel
DE3776198D1 (de) Kuenstliche gefaesswand.
ATE98111T1 (de) Klinische entwicklungen mit amnionzellen.
ATE277648T1 (de) Kollagenmembran mit makromolekularer anordnung
DK158560C (da) Absorberende indlaeg, trusser til behandling af urinal inkontinens og fremgangsmaade til fremstilling af absorberende indlaeg
DE50103247D1 (de) Knochenersatzmaterial
EP0853942A3 (en) Chimeric kidney
ATE288485T1 (de) Monoklonaler antikörper 4g8b4b12 gegen humanes flt3/flk2
IT8125104A0 (it) Dispositivo per raccogliere l'urina di pazienti incontinenti.
FR2659347B1 (fr) Dispositif de culture de cellules assurant leur immobilisation.
NO20032977L (no) Anvendelse av biologisk materiale inneholdende tredimensjonale oppsatsstrukturer av hyaluronsyrederivater for fremstilling av implantater i forbindelse med artroskopi.
EP0747046A3 (en) Permeable immunoisolation membrane structures for implantation of cells in host tissue
KR970006249A (ko) 정수장 오니를 이용한 다공질의 인공토 제조 방법
Ørstavik et al. Localization of glandular kallikreins and secretion of kallikrein from the major salivary glands of the rat
Watanabe et al. Ultrastructure of the zoospores of the coenocytic algae Ascochloris and Urnella (Chlorophyceae), with emphasis on the flagellar apparatus
Surina et al. Pathogenesis of Audiogenic Epilepsy: Altered Proinflammatory Cytokine Levels in the Rats of Krushinsky–Molodkina Seizure-Prone Strain
MX9703321A (es) Tejido in vitro y modelos de organos equivalentes.
Harada et al. The auditory ossicular chain

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties