ATE257943T1 - ELECTROCHEMICAL AND PHOTOCHEMICAL ELECTRODES AND THEIR USE - Google Patents

ELECTROCHEMICAL AND PHOTOCHEMICAL ELECTRODES AND THEIR USE

Info

Publication number
ATE257943T1
ATE257943T1 AT97922016T AT97922016T ATE257943T1 AT E257943 T1 ATE257943 T1 AT E257943T1 AT 97922016 T AT97922016 T AT 97922016T AT 97922016 T AT97922016 T AT 97922016T AT E257943 T1 ATE257943 T1 AT E257943T1
Authority
AT
Austria
Prior art keywords
fad
enzyme
moiety
electrodes
group
Prior art date
Application number
AT97922016T
Other languages
German (de)
Inventor
Itamar Willner
Eugeny Katz
Ron Blonder
Vered Heleg-Shabtai
Original Assignee
Yissum Res Dev Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yissum Res Dev Co filed Critical Yissum Res Dev Co
Application granted granted Critical
Publication of ATE257943T1 publication Critical patent/ATE257943T1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/004—Enzyme electrodes mediator-assisted

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Hybrid Cells (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)

Abstract

Electrodes carrying FAD-dependent enzymes on their surface are enclosed. The FAD is modified to include a functional group or moiety which affects the properties of the enzyme. The functional group or moiety can be a binding moiety through which the FAD-enzyme complex is immobilized onto the electrode; it can be an electron mediator group for transferring electrons between the electrode and the FAD; or it can be a photoisomerizable group which can undergo photoisomerization which yields a change in the rate of the electrically induced catalytic activity of the enzyme. The electrodes can be used in electrochemical systems for deforming analytes in liquid medium or for recordal of optical signals.
AT97922016T 1996-05-27 1997-05-27 ELECTROCHEMICAL AND PHOTOCHEMICAL ELECTRODES AND THEIR USE ATE257943T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL11843296A IL118432A (en) 1996-05-27 1996-05-27 Electrochemical and photochemical electrodes and their use
PCT/IL1997/000169 WO1997045720A1 (en) 1996-05-27 1997-05-27 Electrochemical and photochemical electrodes and their use

Publications (1)

Publication Number Publication Date
ATE257943T1 true ATE257943T1 (en) 2004-01-15

Family

ID=11068904

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97922016T ATE257943T1 (en) 1996-05-27 1997-05-27 ELECTROCHEMICAL AND PHOTOCHEMICAL ELECTRODES AND THEIR USE

Country Status (8)

Country Link
US (1) US6350368B1 (en)
EP (1) EP1002229B1 (en)
AT (1) ATE257943T1 (en)
AU (1) AU2786997A (en)
DE (1) DE69727250T2 (en)
ES (1) ES2214620T3 (en)
IL (1) IL118432A (en)
WO (1) WO1997045720A1 (en)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPP250398A0 (en) * 1998-03-20 1998-04-23 Usf Filtration And Separations Group Inc. Sensor with improved shelf life
US6652734B1 (en) 1999-03-16 2003-11-25 Lifescan, Inc. Sensor with improved shelf life
AU2001227020A1 (en) 2000-01-19 2001-07-31 Given Imaging Ltd. A system for detecting substances
AU2001265403A1 (en) * 2000-05-26 2001-12-11 Minerva Biotechnologies Corporation Metallocenes as signal-transducer for detection of chemical or biological events
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
US7041068B2 (en) 2001-06-12 2006-05-09 Pelikan Technologies, Inc. Sampling module device and method
JP3672099B2 (en) * 2001-06-14 2005-07-13 松下電器産業株式会社 Biosensor
EP1279742A1 (en) * 2001-07-23 2003-01-29 Applied NanoSystems B.V. Method of binding a compound to a sensor surface using hydrophobin
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US7198606B2 (en) 2002-04-19 2007-04-03 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with analyte sensing
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
DK1587839T3 (en) * 2003-01-22 2009-02-16 Bionanophotonics As Light-induced immobilization
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
US8282576B2 (en) 2003-09-29 2012-10-09 Sanofi-Aventis Deutschland Gmbh Method and apparatus for an improved sample capture device
US9351680B2 (en) 2003-10-14 2016-05-31 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a variable user interface
WO2005065414A2 (en) 2003-12-31 2005-07-21 Pelikan Technologies, Inc. Method and apparatus for improving fluidic flow and sample capture
EP1751546A2 (en) 2004-05-20 2007-02-14 Albatros Technologies GmbH & Co. KG Printable hydrogel for biosensors
US9775553B2 (en) 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
US9820684B2 (en) 2004-06-03 2017-11-21 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
US20060003400A1 (en) * 2004-06-30 2006-01-05 Byrd Patricia A Methods and compositions for characterizing a redox reagent system enzyme
US8738106B2 (en) 2005-01-31 2014-05-27 Given Imaging, Ltd Device, system and method for in vivo analysis
CA2610294C (en) 2005-05-09 2023-10-03 Theranos, Inc. Point-of-care fluidic systems and uses thereof
WO2007000163A1 (en) * 2005-06-27 2007-01-04 Bionanophotonics A/S Immobilisation of polypeptides by irradiation
US11287421B2 (en) 2006-03-24 2022-03-29 Labrador Diagnostics Llc Systems and methods of sample processing and fluid control in a fluidic system
US8663093B2 (en) 2006-04-03 2014-03-04 Given Imaging Ltd. Device, system and method for in-vivo analysis
US8007999B2 (en) 2006-05-10 2011-08-30 Theranos, Inc. Real-time detection of influenza virus
US8012744B2 (en) 2006-10-13 2011-09-06 Theranos, Inc. Reducing optical interference in a fluidic device
US20080113391A1 (en) 2006-11-14 2008-05-15 Ian Gibbons Detection and quantification of analytes in bodily fluids
DE102006057612A1 (en) * 2006-12-05 2008-06-12 Studiengesellschaft Kohle Mbh New spiro compounds useful as photo-adjustable catalysts in organic synthesis and as photo-catalysts in the polymerization reaction
US8158430B1 (en) 2007-08-06 2012-04-17 Theranos, Inc. Systems and methods of fluidic sample processing
EP3181228B1 (en) 2007-10-02 2020-07-29 Labrador Diagnostics LLC Modular point-of-care devices and uses thereof
EP2265324B1 (en) 2008-04-11 2015-01-28 Sanofi-Aventis Deutschland GmbH Integrated analyte measurement system
US20100072062A1 (en) * 2008-05-05 2010-03-25 Edwards Lifesciences Corporation Membrane For Use With Amperometric Sensors
US8515507B2 (en) 2008-06-16 2013-08-20 Given Imaging Ltd. Device and method for detecting in-vivo pathology
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
NZ624935A (en) 2009-10-19 2016-01-29 Theranos Inc Integrated health data capture and analysis system
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
RU2620922C2 (en) 2011-01-21 2017-05-30 Теранос, Инк. Systems and methods for optimization of sample use
DK3194962T3 (en) * 2014-09-15 2019-07-01 Qorvo Us Inc Mass detection via redox coupling
US20160250392A1 (en) 2015-02-26 2016-09-01 Battelle Memorial Instute Implant with reactive oxygen species scavenging coating

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU593439A1 (en) * 1975-08-04 1980-10-07 Ордена Трудового Красного Знамени Институт Химических Наук Ан Казахской Сср Method of producing electroconductive ferment-cofactor systems
JPH0815431B2 (en) * 1985-11-13 1996-02-21 相沢 益男 Conductive enzyme membrane
US4704193A (en) * 1986-05-14 1987-11-03 Gte Laboratories Incorporated Covalently coupled cofactor modified electrodes and methods of synthesis and use
US4797181A (en) * 1987-08-03 1989-01-10 Gte Laboratories Incorporated Flavin cofactor modified electrodes and methods of synthesis and use
DE4118880C2 (en) * 1991-06-08 1998-12-17 Fraunhofer Ges Forschung Method for the selective determination of the concentration of dissolved substances in enzymatic reactions
IL102930A (en) 1992-08-25 1997-03-18 Yissum Res Dev Co Electrobiochemical analytical method and electrodes

Also Published As

Publication number Publication date
ES2214620T3 (en) 2004-09-16
IL118432A (en) 1999-12-31
EP1002229B1 (en) 2004-01-14
DE69727250D1 (en) 2004-02-19
US6350368B1 (en) 2002-02-26
WO1997045720A1 (en) 1997-12-04
EP1002229A1 (en) 2000-05-24
IL118432A0 (en) 1996-09-12
AU2786997A (en) 1998-01-05
DE69727250T2 (en) 2004-11-04

Similar Documents

Publication Publication Date Title
DE69727250D1 (en) ELECTROCHEMICAL AND PHOTOCHEMICAL ELECTRODES AND THEIR USE
Lion-Dagan et al. Amperometric transduction of optical signals recorded by organized monolayers of photoisomerizable biomaterials on Au electrodes
Khan et al. Electrochemical behaviour of monolayer quinoprotein adsorbed on the electrode surface
IL116921A (en) Electrochemical system for determination of an analyte in a liquid medium
ES2177586T3 (en) AN ELECTROBIOCHEMICAL PROCEDURE, SYSTEM AND ELECTRODES TO DETERMINE A MEMBER OF A RECOGNITION COUPLE.
EP0771867A3 (en) Enzyme electrode
DE69730612D1 (en) ELECTRODES AND THEIR USE IN ASSAYS
EP0333860A4 (en) Enzymatic sensor
DE50110361D1 (en) ENZYME CATALYSIS IN THE PRESENCE OF IONIC LIQUIDS
JPS6239900B2 (en)
Katz et al. Control of electrochemical processes by photoisomerizable spiropyran monolayers immobilized onto Au electrodes: amperometric transduction of optical signals
AUPO128096A0 (en) Biosensors
Shan et al. A composite poly azure B–clay–enzyme sensor for the mediated electrochemical determination of phenols
DE68912702D1 (en) Porous carbon electrode substrates for fuel cells.
GB9009761D0 (en) Substrate regenerating biosensor
Savitri et al. Electrochemistry of reconstituted glucose oxidase on carbon paste electrodes
GB2301441A (en) Hexacyanoferrate modified electrodes
ES2180543T3 (en) SELECTION BASED ON REACTIONS FOR THE EXPRESSION OF, AND THE CONCENTRATION OF, CATALITICAL REMAINS.
Staškevičien et al. Reagentless lactate electrodes based on electrocatalytic oxidation of flavocytochrome b2
NO954216D0 (en) Peroxidase Colloidal Gold Oxidase Biosensors for Mediatorless Glucose Determination
JPS6343705B2 (en)
GB2230606A (en) Bioelectrochemical reactions in organic solvents
IT1261493B (en) Very high sensitivity porous matrix biosensor and process for the same
AU4041593A (en) Enzymatic biosensor for assaying glycerol in liquid medium
Wingard Jr Innovation in Enzyme Engineering

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties