ATE253556T1 - Aminoacylaroylpyrrole für die behandlung des neuropathischen schmerzes - Google Patents

Aminoacylaroylpyrrole für die behandlung des neuropathischen schmerzes

Info

Publication number
ATE253556T1
ATE253556T1 AT00911850T AT00911850T ATE253556T1 AT E253556 T1 ATE253556 T1 AT E253556T1 AT 00911850 T AT00911850 T AT 00911850T AT 00911850 T AT00911850 T AT 00911850T AT E253556 T1 ATE253556 T1 AT E253556T1
Authority
AT
Austria
Prior art keywords
aminoacylaroylpyrroles
treatment
neuropathic pain
neuropathic
pain
Prior art date
Application number
AT00911850T
Other languages
English (en)
Inventor
John R Carson
Philip M Pitis
Kathryn E Rogers
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Application granted granted Critical
Publication of ATE253556T1 publication Critical patent/ATE253556T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/333—Radicals substituted by oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/335—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
AT00911850T 1999-02-18 2000-02-17 Aminoacylaroylpyrrole für die behandlung des neuropathischen schmerzes ATE253556T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12047799P 1999-02-18 1999-02-18
PCT/US2000/004063 WO2000048584A2 (en) 1999-02-18 2000-02-17 Aroyl aminoacyl pyrroles for use in the treatment of neuropathic pain

Publications (1)

Publication Number Publication Date
ATE253556T1 true ATE253556T1 (de) 2003-11-15

Family

ID=22390558

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00911850T ATE253556T1 (de) 1999-02-18 2000-02-17 Aminoacylaroylpyrrole für die behandlung des neuropathischen schmerzes

Country Status (14)

Country Link
US (2) US6191142B1 (de)
EP (1) EP1154996B1 (de)
JP (1) JP2002537247A (de)
AR (1) AR022620A1 (de)
AT (1) ATE253556T1 (de)
AU (1) AU3367500A (de)
CA (1) CA2361390A1 (de)
DE (1) DE60006363T2 (de)
DK (1) DK1154996T3 (de)
ES (1) ES2209843T3 (de)
HK (1) HK1041003B (de)
TR (1) TR200103219T2 (de)
TW (1) TW562797B (de)
WO (1) WO2000048584A2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002002521A2 (en) * 2000-06-30 2002-01-10 Ortho-Mcneil Pharmaceutical, Inc. Aroyl aminoacyl pyrrole compounds and their pharmaceutical use
WO2002057253A2 (en) * 2000-12-20 2002-07-25 Ortho-Mcneil Pharmaceutical, Inc. Isoindolyl and isoquinolinyl aroyl pyrrole compounds for the treatment of central nervous system disorders
DE60219687T2 (de) * 2001-12-27 2007-12-27 Ortho-Mcneil Pharmaceutical, Inc. Aroylpyrrolheteroeryl und methanole zur behandlung von störungen des zentralnervensystems
EP1481673A4 (de) 2002-02-05 2008-09-24 Ajinomoto Kk Medizinische zusammensetzungen mit gabapentin oder pregabalin und kalziumkanalantagonist vom n-typ
HU230403B1 (hu) * 2003-12-19 2016-04-28 Pál Kocsis Nátrium csatorna blokkoló és szerotonin újrafelvétel gátló tartalmú gyógyszerkészítmény
EP2256103A1 (de) 2009-05-07 2010-12-01 Biosynth AG Neue Anzeigerplattform

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5332736A (en) 1993-11-01 1994-07-26 Ortho Pharmaceutical Corporation Anti-convulsant aroyl aminoacylpyrroles
US5418236A (en) * 1993-12-23 1995-05-23 Ortho Pharmaceutical Corporation Anxiolytic aroyl piperidinyl and piperazinylacyl pyrroles
EP0942752B1 (de) * 1996-08-23 2005-04-20 Algos Pharmaceutical Corporation Antikonvulsive mitteln enthaltende zubereitung zur behandlung von neuropathischen schmerzen
US5760007A (en) 1997-07-16 1998-06-02 Ortho Pharmaceutical Corporation Anticonvulsant derivatives useful in treating neuropathic pain

Also Published As

Publication number Publication date
DE60006363T2 (de) 2005-07-21
DE60006363D1 (de) 2003-12-11
EP1154996B1 (de) 2003-11-05
JP2002537247A (ja) 2002-11-05
US20010044452A1 (en) 2001-11-22
CA2361390A1 (en) 2000-08-24
AU3367500A (en) 2000-09-04
TR200103219T2 (tr) 2002-04-22
HK1041003B (en) 2004-05-07
EP1154996A2 (de) 2001-11-21
WO2000048584A2 (en) 2000-08-24
TW562797B (en) 2003-11-21
AR022620A1 (es) 2002-09-04
ES2209843T3 (es) 2004-07-01
HK1041003A1 (en) 2002-06-28
DK1154996T3 (da) 2004-02-16
WO2000048584A3 (en) 2000-12-07
US6191142B1 (en) 2001-02-20
US6369228B2 (en) 2002-04-09

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