ATE253047T1 - Verbindungen mit (2.2.1)bicyclischer molekülstruktur - Google Patents

Verbindungen mit (2.2.1)bicyclischer molekülstruktur

Info

Publication number
ATE253047T1
ATE253047T1 AT98941734T AT98941734T ATE253047T1 AT E253047 T1 ATE253047 T1 AT E253047T1 AT 98941734 T AT98941734 T AT 98941734T AT 98941734 T AT98941734 T AT 98941734T AT E253047 T1 ATE253047 T1 AT E253047T1
Authority
AT
Austria
Prior art keywords
compounds
molecular structure
provides
systemic
bicyclic
Prior art date
Application number
AT98941734T
Other languages
English (en)
Inventor
Tsunetoshi Honma
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Application granted granted Critical
Publication of ATE253047T1 publication Critical patent/ATE253047T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT98941734T 1997-09-19 1998-09-07 Verbindungen mit (2.2.1)bicyclischer molekülstruktur ATE253047T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP25400297 1997-09-19
PCT/JP1998/003991 WO1999015502A1 (fr) 1997-09-19 1998-09-07 Composes ayant un squelette [2.2.1]bicyclo

Publications (1)

Publication Number Publication Date
ATE253047T1 true ATE253047T1 (de) 2003-11-15

Family

ID=17258903

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98941734T ATE253047T1 (de) 1997-09-19 1998-09-07 Verbindungen mit (2.2.1)bicyclischer molekülstruktur

Country Status (7)

Country Link
US (1) US6225336B1 (de)
EP (1) EP1016660B1 (de)
AT (1) ATE253047T1 (de)
AU (1) AU8998298A (de)
DE (1) DE69819350T2 (de)
TW (1) TW550240B (de)
WO (1) WO1999015502A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4834224B2 (ja) 1999-03-05 2011-12-14 デューク ユニバーシティ C16不飽和fp−選択的プロスタグランジン類縁体
AU2825000A (en) * 1999-03-10 2000-09-28 Shionogi & Co., Ltd. Medicinal compositions with (2.2.1) and (3.1.1) bicycloskeleton antagonistic to both of pgd2/txa2 receptors
US6894175B1 (en) 1999-08-04 2005-05-17 The Procter & Gamble Company 2-Decarboxy-2-phosphinico prostaglandin derivatives and methods for their preparation and use
US20020037914A1 (en) 2000-03-31 2002-03-28 Delong Mitchell Anthony Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins
US20020013294A1 (en) 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
US20020172693A1 (en) 2000-03-31 2002-11-21 Delong Michell Anthony Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
AU2001260627A1 (en) 2000-06-02 2001-12-17 Shionogi And Co., Ltd. Drug composition antagonistic to both pgd2/txa2 receptors
AU2001268051A1 (en) 2000-06-28 2002-01-08 Eli Lilly And Company Spla2 inhibitors
EP1338594A4 (de) * 2000-11-01 2004-06-16 Shionogi & Co Pharmazeutische zusammensetzungen mit pgd2-rezeptor-antagonistischer wirkung
CA2454347A1 (en) * 2001-07-18 2003-01-30 Merck Frosst Canada & Co./Merck Frosst Canada & Cie Eosinophil prostaglandin d2 receptor assays
US20040197834A1 (en) * 2001-07-20 2004-10-07 Francois Gervais Method to increase expression of pgd2 receptors and assays for identifying modulators of prostaglandin d2 receptors
JP4424155B2 (ja) * 2004-10-27 2010-03-03 富士通株式会社 移動通信システム、移動局
US8623918B2 (en) 2008-10-29 2014-01-07 Novaer Holdings, Inc. Amino acid salts of prostaglandins
US8722739B2 (en) 2008-10-29 2014-05-13 Novaer Holdings, Inc. Amino acid salts of prostaglandins

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6149A (ja) 1984-06-12 1986-01-06 Ono Pharmaceut Co Ltd 新規な13―アザ―14―オキソ―TxA2類似化合物およびそれらを有効成分として含有するトロンボキサン起因疾患治療剤
NZ218115A (en) 1985-11-18 1990-02-26 Shionogi & Co Bicyclic sulphonamides and pharmaceutical compositions
JPH0353295A (ja) 1989-07-21 1991-03-07 Kenji Furuhashi 電子風鈴
DK0837052T3 (da) 1995-06-21 2007-01-02 Shionogi & Co Bicykliske aminoderivater og PGD2-antagonist indeholdende disse
WO2000030683A1 (fr) * 1998-11-19 2000-06-02 Shionogi & C0., Ltd. Composes prophylactiques et/ou therapeutiques destines a des maladies du systeme nerveux central et possedant des composes antagonistes du recepteur de txa2 et/ou inhibiteurs de la txa2 synthase
AU2825000A (en) * 1999-03-10 2000-09-28 Shionogi & Co., Ltd. Medicinal compositions with (2.2.1) and (3.1.1) bicycloskeleton antagonistic to both of pgd2/txa2 receptors

Also Published As

Publication number Publication date
DE69819350D1 (de) 2003-12-04
TW550240B (en) 2003-09-01
US6225336B1 (en) 2001-05-01
EP1016660A1 (de) 2000-07-05
DE69819350T2 (de) 2004-07-22
EP1016660A4 (de) 2001-04-11
WO1999015502A1 (fr) 1999-04-01
EP1016660B1 (de) 2003-10-29
AU8998298A (en) 1999-04-12

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties