ATE250573T1 - Azetidin- und pyrrolidinderivate - Google Patents
Azetidin- und pyrrolidinderivateInfo
- Publication number
- ATE250573T1 ATE250573T1 AT97200536T AT97200536T ATE250573T1 AT E250573 T1 ATE250573 T1 AT E250573T1 AT 97200536 T AT97200536 T AT 97200536T AT 97200536 T AT97200536 T AT 97200536T AT E250573 T1 ATE250573 T1 AT E250573T1
- Authority
- AT
- Austria
- Prior art keywords
- alkoxy
- alkyl
- azetidine
- naphth
- pyrrolidin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/12—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP97200536A EP0863136B1 (de) | 1997-02-25 | 1997-02-25 | Azetidin- und Pyrrolidinderivate |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE250573T1 true ATE250573T1 (de) | 2003-10-15 |
Family
ID=8228047
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT97200536T ATE250573T1 (de) | 1997-02-25 | 1997-02-25 | Azetidin- und pyrrolidinderivate |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0863136B1 (de) |
AT (1) | ATE250573T1 (de) |
AU (1) | AU754745B2 (de) |
DE (1) | DE69725113T2 (de) |
DK (1) | DK0863136T3 (de) |
ES (1) | ES2208812T3 (de) |
HK (1) | HK1010881A1 (de) |
PT (1) | PT863136E (de) |
WO (1) | WO1999043647A1 (de) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE247104T1 (de) | 1997-11-05 | 2003-08-15 | Neurosearch As | Azaring-ether-derivate und ihre verwendung als nicotinic-ach-rezeptormodulatoren |
KR20010073153A (ko) | 1998-09-18 | 2001-07-31 | 제임스 에이. 아노 | 녹내장 치료용의 세로토닌성 5ht2 작용제 |
US6465467B1 (en) | 1999-05-21 | 2002-10-15 | Biovitrum Ab | Certain aryl-aliphatic and heteroaryl-aliphatic piperazinyl pyrazines and their use in the treatment of serotonin-related diseases |
SE0004245D0 (sv) | 2000-11-20 | 2000-11-20 | Pharmacia Ab | Novel compounds and their use |
NZ525699A (en) | 2000-11-20 | 2005-03-24 | Biovitrum Ab | Piperazinylpyrazines compounds as antagonists of serotonin 5-HT2 receptor |
US6498184B2 (en) | 2000-12-05 | 2002-12-24 | Akzo Nobel N.V. | Serotonergic compound for a method of treatment of hot flushes in post-menopausal women |
EP1213017A3 (de) * | 2000-12-05 | 2003-11-12 | Akzo Nobel N.V. | Verwendung von einem 5-HT2C Rezeptor Agonist zur Behandlung von Hitzewallungen |
ATE454383T1 (de) | 2002-06-19 | 2010-01-15 | Biovitrum Ab Publ | Neue verbindungen, deren verwendung und herstellung |
WO2004009555A1 (ja) * | 2002-07-22 | 2004-01-29 | Asahi Kasei Pharma Corporation | 5−置換イソキノリン誘導体 |
US7094789B2 (en) | 2002-07-22 | 2006-08-22 | Asahi Kasei Pharma Corporation | 5-substituted isoquinoline derivatives |
CL2004000826A1 (es) | 2003-04-25 | 2005-03-04 | Pfizer | Uso de un agonista para el receptor 5-ht2c para preparar un medicamento util en el tratamiento de la incontinencia urinaria provocada por estres, con la condicion de que el agonista no sea 1-[6-cloro-5-(trifluorometil)-2-piridinil]piperazina (org-129 |
US20070021404A1 (en) * | 2003-06-24 | 2007-01-25 | Dan Peters | Novel aza-ring derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
WO2006022420A1 (ja) | 2004-08-25 | 2006-03-02 | Takeda Pharmaceutical Company Limited | 腹圧性尿失禁の予防・治療剤及びそのスクリーニング方法 |
MX2007012082A (es) | 2005-03-31 | 2007-11-20 | Pfizer Prod Inc | Derivados de ciclopentapiridina y tetrahidroquinolina. |
WO2007132841A1 (ja) | 2006-05-16 | 2007-11-22 | Takeda Pharmaceutical Company Limited | 縮合複素環化合物およびその用途 |
US8748419B2 (en) | 2006-06-16 | 2014-06-10 | Theracos, Inc. | Treating obesity with muscarinic receptor M1 antagonists |
US7893053B2 (en) | 2006-06-16 | 2011-02-22 | Theracos, Inc. | Treating psychological conditions using muscarinic receptor M1 antagonists |
US8143424B2 (en) | 2007-06-06 | 2012-03-27 | Torrent Pharmaceuticals Ltd. | Thyroid like compounds |
WO2009063992A1 (ja) | 2007-11-15 | 2009-05-22 | Takeda Pharmaceutical Company Limited | 縮合ピリジン誘導体およびその用途 |
FR2925050B1 (fr) * | 2007-12-14 | 2010-01-08 | Sanofi Aventis | Nouveau procede de preparation de derives d'azetidine |
KR101062376B1 (ko) | 2008-04-10 | 2011-09-06 | 한국화학연구원 | 신규 인돌 카르복실산 비스피리딜 카르복사마이드 유도체,이의 제조방법 및 이를 유효성분으로 함유하는 조성물 |
WO2010059390A1 (en) | 2008-10-30 | 2010-05-27 | Janssen Pharmaceutica Nv | Modulators of serotonin receptor |
US8642583B2 (en) | 2008-10-30 | 2014-02-04 | Janssen Pharmaceutica Nv | Serotonin receptor modulators |
JPWO2011071136A1 (ja) | 2009-12-11 | 2013-04-22 | アステラス製薬株式会社 | 線維筋痛症治療剤 |
WO2012030953A1 (en) | 2010-09-01 | 2012-03-08 | Arena Pharmaceuticals, Inc. | 5-ht2c receptor agonists in the treatment of disorders ameliorated by reduction of norepinephrine level |
KR101426408B1 (ko) * | 2013-02-19 | 2014-08-07 | 한국과학기술연구원 | 4각 고리 질소 화합물, 이를 포함하는 우울증, 정신 질환, 조루증, 또는 신경병증성 통증의 예방 또는 치료용 약학 조성물, 및 상기 약학 조성물을 포함하는 제제 |
WO2015066344A1 (en) | 2013-11-01 | 2015-05-07 | Arena Pharmaceuticals, Inc. | 5-ht2c receptor agonists and compositions and methods of use |
CN105237381A (zh) * | 2015-10-14 | 2016-01-13 | 湖南华腾制药有限公司 | 5-羟基-1-茚酮的制备方法 |
CN105330525A (zh) * | 2015-10-25 | 2016-02-17 | 湖南华腾制药有限公司 | 7-羟基-1-茚酮的制备方法 |
US20210052600A1 (en) | 2017-12-27 | 2021-02-25 | Takeda Pharmaceutical Company Limited | Therapeutic agents for stress urinary incontinence and incotinence of feces |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2085427B (en) * | 1980-10-08 | 1984-12-05 | Robins Co Inc A H | 3-phenoxyazetidines |
DE3835291A1 (de) * | 1988-04-19 | 1989-11-02 | Bayer Ag | 1,3-disubstituierte pyrrolidine |
US5130309A (en) * | 1991-04-12 | 1992-07-14 | A. H. Robins Company, Incorporated | Aryloxy and aryloxyalklazetidines as antiarrhythmic and anticonvulsant agents |
-
1997
- 1997-02-25 DK DK97200536T patent/DK0863136T3/da active
- 1997-02-25 ES ES97200536T patent/ES2208812T3/es not_active Expired - Lifetime
- 1997-02-25 DE DE69725113T patent/DE69725113T2/de not_active Expired - Lifetime
- 1997-02-25 EP EP97200536A patent/EP0863136B1/de not_active Expired - Lifetime
- 1997-02-25 PT PT97200536T patent/PT863136E/pt unknown
- 1997-02-25 AT AT97200536T patent/ATE250573T1/de active
-
1998
- 1998-02-26 AU AU65002/98A patent/AU754745B2/en not_active Ceased
- 1998-02-26 WO PCT/EP1998/001282 patent/WO1999043647A1/en active IP Right Grant
- 1998-11-20 HK HK98112152A patent/HK1010881A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0863136A1 (de) | 1998-09-09 |
HK1010881A1 (en) | 1999-07-02 |
AU6500298A (en) | 1999-09-15 |
PT863136E (pt) | 2004-01-30 |
ES2208812T3 (es) | 2004-06-16 |
WO1999043647A1 (en) | 1999-09-02 |
DE69725113T2 (de) | 2004-07-15 |
AU754745B2 (en) | 2002-11-21 |
DK0863136T3 (da) | 2004-02-02 |
EP0863136B1 (de) | 2003-09-24 |
DE69725113D1 (de) | 2003-10-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK0863136T3 (da) | Azetidin- og pyrrolidinderivater | |
CA2321188A1 (en) | Derivatives of azetidine and pyrrolidine | |
CY1105863T1 (el) | Παραγωγα εποθιλονης και η συνθεση και η χρηση τους | |
LU91210I2 (fr) | Emodepside & Praziquantel ainsi que leurs dérivés pharmaceutiqement acceptables (PROFENDER) | |
NZ237565A (en) | Substituted thiazolidinones, oxazolidinones or imidazolidinones and antiinflammatory pharmaceutical compositions thereof | |
FI950309A0 (fi) | Proliiniamidijohdannaisia | |
DE69803750D1 (de) | Thiazolidinedione- und oxazolidinedione-derivate mit antidiabetischen, hypolipidämischen und anti hypertensiven eigenschaften | |
ATE173256T1 (de) | Azolidindion-derivate und ihre anwendung als antihyperglykämika | |
NO934833D0 (no) | Thiazolidinedionderivater, deres fremstilling og anvendelse | |
DK132188D0 (da) | Anvendelse af tetrahydrobenz(c,d)indol-6-carboxamider som anxiolytika | |
KR960704878A (ko) | 광학 활성 이미다졸리딘온 유도체 및 이의 제조방법 (Optically active imidazolidinone derivative and process for producing the same) | |
ES2148561T3 (es) | Prevencion y curacion de enfermedades alergicas de tipo i. | |
ES2106439T3 (es) | 5-(piperazinilalquil)-1,5-benzotiazepinonas utiles como antagonistas de calcio. | |
ATE63541T1 (de) | N-phenylethylaminoalkyl-benzamide als antiarrhythmische mittel. | |
ATE146481T1 (de) | Epoxysuccinamidsäurederivat | |
ATE269862T1 (de) | Substituierte thiazolidinedione und oxazolidinedione mit antidiabetischen, hypolipidämischen und antihypertensiven eigenschaften | |
BE1002181A3 (fr) | 3-(2-haloalkyl)-1,4-oxathiines et 2-(2-haloalkyl)-1,4-dithiines, de meme que le traitement de la leucemie et des tumeurs avec ces substances. | |
NO893039D0 (no) | Bruk av imidazopyrazol-derivater som analgesiske og antiinflammatoriske midler. | |
ATE144900T1 (de) | Verwendung von xanthinderivaten gegen magengeschwüre | |
DE69327077T2 (de) | Carbamoylpyrrolidon-Derivate zur Behandlung von Depressionen und cerebrovasculären Störungen | |
BR9815690A (pt) | Composto, processo para a preparação de qualquer um dos compostos, composição farmacêutica, e, uso do composto de 3-(nafter-1-il-óxi) - pirrolidina, 3-(5,6,7,8 - tetraidro-nafterc-1-il-óxi) - pirrolindina |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 0863136 Country of ref document: EP |