ATE243515T1 - Verwendung der angiotensin ii-antagonisten losartan und exp-3174 zur behandlung von symptomatisches herzversagen - Google Patents
Verwendung der angiotensin ii-antagonisten losartan und exp-3174 zur behandlung von symptomatisches herzversagenInfo
- Publication number
- ATE243515T1 ATE243515T1 AT98903447T AT98903447T ATE243515T1 AT E243515 T1 ATE243515 T1 AT E243515T1 AT 98903447 T AT98903447 T AT 98903447T AT 98903447 T AT98903447 T AT 98903447T AT E243515 T1 ATE243515 T1 AT E243515T1
- Authority
- AT
- Austria
- Prior art keywords
- heart failure
- angiotensin
- symptomatic heart
- exp
- treatment
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3492797P | 1997-01-10 | 1997-01-10 | |
| GBGB9704197.4A GB9704197D0 (en) | 1997-02-28 | 1997-02-28 | Method for reducing mortality with an angiotensin 11 antagonist |
| PCT/US1998/000534 WO1998030216A1 (en) | 1997-01-10 | 1998-01-07 | Use of angiotensin ii antagonists to treat symptomatic heart failure |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE243515T1 true ATE243515T1 (de) | 2003-07-15 |
Family
ID=26311085
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98903447T ATE243515T1 (de) | 1997-01-10 | 1998-01-07 | Verwendung der angiotensin ii-antagonisten losartan und exp-3174 zur behandlung von symptomatisches herzversagen |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0966282B1 (de) |
| JP (1) | JP2000508347A (de) |
| KR (1) | KR20000070046A (de) |
| CN (1) | CN1249682A (de) |
| AT (1) | ATE243515T1 (de) |
| AU (1) | AU729881B2 (de) |
| CA (1) | CA2277018C (de) |
| DE (1) | DE69815822T2 (de) |
| DK (1) | DK0966282T3 (de) |
| EA (1) | EA199900635A1 (de) |
| EE (1) | EE9900278A (de) |
| ES (1) | ES2200310T3 (de) |
| HU (1) | HUP0000108A2 (de) |
| IL (1) | IL130599A0 (de) |
| NO (1) | NO993399L (de) |
| PT (1) | PT966282E (de) |
| SK (1) | SK92899A3 (de) |
| WO (1) | WO1998030216A1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000027397A1 (en) * | 1998-11-06 | 2000-05-18 | Glaxo Group Limited | Antihypertensive medicaments containing lacidipine and telmisartan |
| SE9902597D0 (sv) * | 1999-07-06 | 1999-07-06 | Astra Ab | New use |
| SE9903028D0 (sv) * | 1999-08-27 | 1999-08-27 | Astra Ab | New use |
| WO2001060362A1 (en) * | 2000-02-18 | 2001-08-23 | Takeda Chemical Industries, Ltd. | TNF-α INHIBITORS |
| JP2005126338A (ja) * | 2003-10-21 | 2005-05-19 | Boehringer Ingelheim Pharma Gmbh & Co Kg | 心不全治療剤 |
| AR078107A1 (es) * | 2009-08-31 | 2011-10-12 | Sanofi Aventis | Uso de irbesartan para la preparacion de un medicamento para la prevencion de la hospitalizacion por insuficiencia cardiaca |
| DK3626270T3 (da) * | 2013-08-26 | 2024-01-15 | Novartis Ag | Behandling af kardiovaskulære sygdomme |
| EP3478672B1 (de) | 2016-06-29 | 2024-04-10 | Université de Montréal | Biarylmethylheterocyclen |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0831910T3 (da) * | 1995-06-07 | 2002-05-21 | Searle & Co | Kombinationsterapi med epoxy-steroid aldosteronantagonist og angiotensin II-receptorantagonist til behandling af kongestivt hjertesvigt |
-
1998
- 1998-01-07 PT PT98903447T patent/PT966282E/pt unknown
- 1998-01-07 IL IL13059998A patent/IL130599A0/xx unknown
- 1998-01-07 KR KR1019997006266A patent/KR20000070046A/ko not_active Application Discontinuation
- 1998-01-07 HU HU0000108A patent/HUP0000108A2/hu unknown
- 1998-01-07 EA EA199900635A patent/EA199900635A1/ru unknown
- 1998-01-07 SK SK928-99A patent/SK92899A3/sk unknown
- 1998-01-07 EP EP98903447A patent/EP0966282B1/de not_active Expired - Lifetime
- 1998-01-07 AT AT98903447T patent/ATE243515T1/de active
- 1998-01-07 DK DK98903447T patent/DK0966282T3/da active
- 1998-01-07 CN CN98803141A patent/CN1249682A/zh active Pending
- 1998-01-07 CA CA002277018A patent/CA2277018C/en not_active Expired - Fee Related
- 1998-01-07 JP JP10531200A patent/JP2000508347A/ja active Pending
- 1998-01-07 EE EEP199900278A patent/EE9900278A/xx unknown
- 1998-01-07 AU AU60218/98A patent/AU729881B2/en not_active Ceased
- 1998-01-07 DE DE69815822T patent/DE69815822T2/de not_active Expired - Lifetime
- 1998-01-07 ES ES98903447T patent/ES2200310T3/es not_active Expired - Lifetime
- 1998-01-07 WO PCT/US1998/000534 patent/WO1998030216A1/en active IP Right Grant
-
1999
- 1999-07-09 NO NO993399A patent/NO993399L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| KR20000070046A (ko) | 2000-11-25 |
| DE69815822D1 (de) | 2003-07-31 |
| CN1249682A (zh) | 2000-04-05 |
| CA2277018A1 (en) | 1998-07-16 |
| NO993399D0 (no) | 1999-07-09 |
| CA2277018C (en) | 2006-10-03 |
| WO1998030216A1 (en) | 1998-07-16 |
| JP2000508347A (ja) | 2000-07-04 |
| EA199900635A1 (ru) | 2000-02-28 |
| AU729881B2 (en) | 2001-02-15 |
| DK0966282T3 (da) | 2003-09-29 |
| EE9900278A (et) | 2000-02-15 |
| EP0966282A1 (de) | 1999-12-29 |
| NO993399L (no) | 1999-09-09 |
| HUP0000108A2 (hu) | 2001-04-28 |
| AU6021898A (en) | 1998-08-03 |
| IL130599A0 (en) | 2000-06-01 |
| ES2200310T3 (es) | 2004-03-01 |
| PT966282E (pt) | 2003-10-31 |
| DE69815822T2 (de) | 2004-05-06 |
| SK92899A3 (en) | 2000-08-14 |
| EP0966282B1 (de) | 2003-06-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TR200002860T2 (tr) | Bir antiviral benzimidazol terkibin yeni kristal formları. | |
| CY1121113T1 (el) | Θεραπεια της νοσου ρομρε | |
| EA200100418A1 (ru) | Комбинированная терапия с применением ингибитора фермента конверсии ангиотензина и антагониста альдостерона для снижения заболеваемости и смертности при сердечно-сосудистых заболеваниях | |
| BR9714363A (pt) | Derivados de pirazol substituìdos para o tratamento de doenças circulatórias cardìacas | |
| TNSN05045A1 (en) | Indole or benzimidazole derivatives for modulating ikappab kinase | |
| DE69738615D1 (de) | Verwendung von glp-1 oder analogen zur behandlung von myokardischem infarkt | |
| ATE209047T1 (de) | Epoxysteroide aldosteronantagonist und angiotensin ii rezeptor antagonist kombinationstherapie zur behandlung von congestivem herzversagen | |
| TR200101470T2 (tr) | Farmasötik bileşim terkipleri. | |
| ATE397457T1 (de) | Stimulierung von t-zellen gegen selbstantigene unter verwendung von ctla-4 inhibierenden wirkstoffen | |
| DE69814394D1 (de) | Verwendung von levobupivacain | |
| DK1572230T3 (da) | Placenta alkalisk phosphatase til at kontrollere diabetes | |
| ATE243515T1 (de) | Verwendung der angiotensin ii-antagonisten losartan und exp-3174 zur behandlung von symptomatisches herzversagen | |
| EE9900450A (et) | Tetrahüdropüridoühendid, neid sisaldav ravim ja nende kasutamine | |
| DE60041974D1 (de) | 5-methylindirubin zur verwendung in der behandlung von menschlichen festen tumoren | |
| ATE333281T1 (de) | Agonisten und antagonisten von benzodiazepinrezeptoren des peripheren typs | |
| ATE297732T1 (de) | Kombinationstherapie zur behandlung von herzinsuffizienz | |
| ATE185274T1 (de) | Therapeutisches mittel gegen drohenden abortus | |
| ATE198271T1 (de) | Syndecan-stimulierung der zellulären differenzierung | |
| Prakash et al. | Brachial plexus with two trunks and double axillary veins: applied importance and clinical implications | |
| EA200000909A1 (ru) | ФОРМА VI 5,6-ДИХЛОР-2-(ИЗОПРОПИЛАМИНО)-1-(b-L-РИБОФУРАНОЗИЛ)-1H-БЕНЗИМИДАЗОЛА | |
| TR199701617T1 (xx) | �iftliklerde �retilen bal�klarda g�r�len parazitlerle m�cadelede kullan�lacak bir ajan. | |
| SE0101328D0 (sv) | Therapeutic treatment | |
| AR021106A1 (es) | Terapia combinada de un inhibidor de la enzima convertidora de angiotensina y un antagonista de aldosterona para reducir la morbilidad y mortalidad porenfermedades cardiovasculares | |
| Neutel et al. | P-373: A comparison of the effects of amlodipine 5 mg/benazepril 20 mg combination therapy to component monotherapy on arterial distensibilitly and left ventricular hypertrophy in patients with mild to moderate hypertension | |
| Beckles et al. | P-375: Attenuation of cardiac hypertrophy in vivo by interference with the jak/Stat pathway |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0966282 Country of ref document: EP |
|
| EEFA | Change of the company name |