ATE2330T1 - 3,7-disubstituierte-2- oder -3-cephem-4carbons[ure-verbindungen, sie enthaltende pharmazeutische zusammensetzungen und verfahren zu deren herstellung. - Google Patents

3,7-disubstituierte-2- oder -3-cephem-4carbons[ure-verbindungen, sie enthaltende pharmazeutische zusammensetzungen und verfahren zu deren herstellung.

Info

Publication number
ATE2330T1
ATE2330T1 AT79104084T AT79104084T ATE2330T1 AT E2330 T1 ATE2330 T1 AT E2330T1 AT 79104084 T AT79104084 T AT 79104084T AT 79104084 T AT79104084 T AT 79104084T AT E2330 T1 ATE2330 T1 AT E2330T1
Authority
AT
Austria
Prior art keywords
cephem
group
disubstituted
compounds
processes
Prior art date
Application number
AT79104084T
Other languages
English (en)
Inventor
Ikuo Ueda
Masakazu Kobayashi
Hisashi Yamada
Hiroki Ono
Original Assignee
Fujisawa Pharmaceutical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co., Ltd. filed Critical Fujisawa Pharmaceutical Co., Ltd.
Application granted granted Critical
Publication of ATE2330T1 publication Critical patent/ATE2330T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
AT79104084T 1978-10-24 1979-10-22 3,7-disubstituierte-2- oder -3-cephem-4carbons[ure-verbindungen, sie enthaltende pharmazeutische zusammensetzungen und verfahren zu deren herstellung. ATE2330T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7841754 1978-10-24
EP79104084A EP0010313B1 (de) 1978-10-24 1979-10-22 3,7-Disubstituierte-2- oder -3-cephem-4-carbonsäure-Verbindungen, sie enthaltende pharmazeutische Zusammensetzungen und Verfahren zu deren Herstellung

Publications (1)

Publication Number Publication Date
ATE2330T1 true ATE2330T1 (de) 1983-02-15

Family

ID=10500550

Family Applications (1)

Application Number Title Priority Date Filing Date
AT79104084T ATE2330T1 (de) 1978-10-24 1979-10-22 3,7-disubstituierte-2- oder -3-cephem-4carbons[ure-verbindungen, sie enthaltende pharmazeutische zusammensetzungen und verfahren zu deren herstellung.

Country Status (5)

Country Link
US (2) US4327093A (de)
EP (1) EP0010313B1 (de)
JP (2) JPS5559195A (de)
AT (1) ATE2330T1 (de)
DE (1) DE2964634D1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4327093A (en) * 1978-10-24 1982-04-27 Fujisawa Pharmaceutical Co., Ltd. 3,7-Disubstituted-2 or 3-cephem-4-carboxylic acid compounds
US4652651A (en) * 1983-05-31 1987-03-24 Hoffmann-La Roche Inc. Process for the manufacture of 1-sulpho-2-oxoazetidine carboxylic acid intermediates via catalytic ester cleavage
IL99898A (en) * 1990-11-09 1996-10-31 Eisai Co Ltd 7-Noble-3- Compounds Transformed Carbamoylloxy
JPH05230068A (ja) * 1992-02-07 1993-09-07 Kyoto Yakuhin Kogyo Kk ３−ジ置換カルバモイルオキシメチルセファロスポリン化合物、その製造法および中間体化合物
EP2862569A1 (de) 2011-09-09 2015-04-22 Cubist Pharmaceuticals, Inc. Verfahren zur Behandlung von intrapulmonalen Infektionen
US8809314B1 (en) 2012-09-07 2014-08-19 Cubist Pharmacueticals, Inc. Cephalosporin compound
US8476425B1 (en) 2012-09-27 2013-07-02 Cubist Pharmaceuticals, Inc. Tazobactam arginine compositions
EP3100732A1 (de) 2013-03-15 2016-12-07 Merck Sharp & Dohme Corp. Antibiotische ceftolozanzusammensetzungen
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
US20140274990A1 (en) 2013-03-15 2014-09-18 Cubist Pharmaceuticals, Inc. Ceftolozane pharmaceutical compositions
EP3043797B1 (de) 2013-09-09 2020-04-08 Merck Sharp & Dohme Corp. Behandlung von infektionen mit ceftolozan/tazobactam bei personen mit beeinträchtigter nierenfunktion
US20150094293A1 (en) 2013-09-27 2015-04-02 Calixa Therapeutics, Inc. Solid forms of ceftolozane

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL36281A (en) 1970-03-13 1977-04-29 Merck & Co Inc History of cephalosporins, antibiotic mixtures that include them and the process for their preparation
SE376250B (de) 1970-05-05 1975-05-12 Basf Ag
US3966717A (en) * 1971-05-14 1976-06-29 Glaxo Laboratories Limited 7-β-Acylamido-3-carbamoyloxymethylceph-3-em-4-carboxylic acids and salts thereof
NL178005C (nl) * 1972-11-06 1986-01-02 Merck & Co Inc Werkwijze voor het bereiden van een farmaceutisch preparaat met antibacteriele werking, alsmede werkwijze ter bereiding van een cefalosporine-antibioticum.
SE7503274L (sv) * 1974-04-11 1975-10-13 Ciba Geigy Ag Cefalosporin
US4011215A (en) * 1974-08-15 1977-03-08 Glaxo Laboratories Limited 3-Chloroalkylcarbamoyloxymethyl-7-[2-(fur-2-yl)-2-methoxyiminoacetamido]ceph-3-em-4-carboxylic acids and physiologically acceptable salts or oxides thereof
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
DE2619243C2 (de) * 1975-05-06 1985-07-04 Takeda Chemical Industries, Ltd., Osaka Verfahren zur Herstellung von 3-Acyloxymethyl-cephem-Verbindungen
JPS5278891A (en) * 1975-12-24 1977-07-02 Asahi Chem Ind Co Ltd Synthesis of cephalosporin antibiotics
US4061630A (en) * 1976-02-20 1977-12-06 Eli Lilly And Company 7-Substituted-ureido-3-carbamoyloxymethyl cephalosporin antibiotics
JPS52125188A (en) * 1976-04-14 1977-10-20 Takeda Chem Ind Ltd Cephalosporin derivatives and their preparation
US4292427A (en) * 1976-11-17 1981-09-29 Merck & Co., Inc. Cephalosporin compounds
US4252974A (en) * 1978-04-07 1981-02-24 Glaxo Group Limited Cephalosporin compounds
US4327093A (en) * 1978-10-24 1982-04-27 Fujisawa Pharmaceutical Co., Ltd. 3,7-Disubstituted-2 or 3-cephem-4-carboxylic acid compounds

Also Published As

Publication number Publication date
US4399278A (en) 1983-08-16
DE2964634D1 (en) 1983-03-03
JPS5559195A (en) 1980-05-02
EP0010313A1 (de) 1980-04-30
JPS6479188A (en) 1989-03-24
JPH0369354B2 (de) 1991-10-31
JPH0144714B2 (de) 1989-09-29
US4327093A (en) 1982-04-27
EP0010313B1 (de) 1983-01-26

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee