DE2964634D1 - 3,7-disubstituted-2- or -3-cephem-4-carboxylic acid compounds, pharmaceutical compositions containing them and processes for the preparation thereof - Google Patents

3,7-disubstituted-2- or -3-cephem-4-carboxylic acid compounds, pharmaceutical compositions containing them and processes for the preparation thereof

Info

Publication number
DE2964634D1
DE2964634D1 DE7979104084T DE2964634T DE2964634D1 DE 2964634 D1 DE2964634 D1 DE 2964634D1 DE 7979104084 T DE7979104084 T DE 7979104084T DE 2964634 T DE2964634 T DE 2964634T DE 2964634 D1 DE2964634 D1 DE 2964634D1
Authority
DE
Germany
Prior art keywords
cephem
preparation
carboxylic acid
group
disubstituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE7979104084T
Other languages
English (en)
Inventor
Ikuo Ueda
Masakazu Kobayashi
Hisashi Yamada
Hiroki Ono
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE2964634D1 publication Critical patent/DE2964634D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE7979104084T 1978-10-24 1979-10-22 3,7-disubstituted-2- or -3-cephem-4-carboxylic acid compounds, pharmaceutical compositions containing them and processes for the preparation thereof Expired DE2964634D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7841754 1978-10-24

Publications (1)

Publication Number Publication Date
DE2964634D1 true DE2964634D1 (en) 1983-03-03

Family

ID=10500550

Family Applications (1)

Application Number Title Priority Date Filing Date
DE7979104084T Expired DE2964634D1 (en) 1978-10-24 1979-10-22 3,7-disubstituted-2- or -3-cephem-4-carboxylic acid compounds, pharmaceutical compositions containing them and processes for the preparation thereof

Country Status (5)

Country Link
US (2) US4327093A (de)
EP (1) EP0010313B1 (de)
JP (2) JPS5559195A (de)
AT (1) ATE2330T1 (de)
DE (1) DE2964634D1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4327093A (en) * 1978-10-24 1982-04-27 Fujisawa Pharmaceutical Co., Ltd. 3,7-Disubstituted-2 or 3-cephem-4-carboxylic acid compounds
US4652651A (en) * 1983-05-31 1987-03-24 Hoffmann-La Roche Inc. Process for the manufacture of 1-sulpho-2-oxoazetidine carboxylic acid intermediates via catalytic ester cleavage
IL113744A (en) * 1990-11-09 1998-06-15 Eisai Co Ltd History of 3-tufts and their preparation
JPH05230068A (ja) * 1992-02-07 1993-09-07 Kyoto Yakuhin Kogyo Kk ３−ジ置換カルバモイルオキシメチルセファロスポリン化合物、その製造法および中間体化合物
WO2013036783A2 (en) 2011-09-09 2013-03-14 Cubist Pharmaceuticals, Inc. Methods for treating intrapulmonary infections
US8809314B1 (en) 2012-09-07 2014-08-19 Cubist Pharmacueticals, Inc. Cephalosporin compound
US8476425B1 (en) 2012-09-27 2013-07-02 Cubist Pharmaceuticals, Inc. Tazobactam arginine compositions
KR102329764B1 (ko) 2013-03-15 2021-11-23 머크 샤프 앤드 돔 코포레이션 세프톨로잔 항균성 조성물
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
US20140274991A1 (en) 2013-03-15 2014-09-18 Cubist Pharmaceuticals, Inc. Ceftolozane pharmaceutical compositions
WO2015035376A2 (en) 2013-09-09 2015-03-12 Calixa Therapeutics, Inc. Treating infections with ceftolozane/tazobactam in subjects having impaired renal function
US8906898B1 (en) 2013-09-27 2014-12-09 Calixa Therapeutics, Inc. Solid forms of ceftolozane

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL36281A (en) 1970-03-13 1977-04-29 Merck & Co Inc History of cephalosporins, antibiotic mixtures that include them and the process for their preparation
CA918327A (en) 1970-05-05 1973-01-02 Haaf Franz Impact-resistant thermoplastic molding material
US3966717A (en) * 1971-05-14 1976-06-29 Glaxo Laboratories Limited 7-β-Acylamido-3-carbamoyloxymethylceph-3-em-4-carboxylic acids and salts thereof
NL178005C (nl) * 1972-11-06 1986-01-02 Merck & Co Inc Werkwijze voor het bereiden van een farmaceutisch preparaat met antibacteriele werking, alsmede werkwijze ter bereiding van een cefalosporine-antibioticum.
SE7503274L (sv) * 1974-04-11 1975-10-13 Ciba Geigy Ag Cefalosporin
US4011215A (en) * 1974-08-15 1977-03-08 Glaxo Laboratories Limited 3-Chloroalkylcarbamoyloxymethyl-7-[2-(fur-2-yl)-2-methoxyiminoacetamido]ceph-3-em-4-carboxylic acids and physiologically acceptable salts or oxides thereof
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
DE2619243C2 (de) * 1975-05-06 1985-07-04 Takeda Chemical Industries, Ltd., Osaka Verfahren zur Herstellung von 3-Acyloxymethyl-cephem-Verbindungen
JPS5278891A (en) * 1975-12-24 1977-07-02 Asahi Chem Ind Co Ltd Synthesis of cephalosporin antibiotics
US4061630A (en) * 1976-02-20 1977-12-06 Eli Lilly And Company 7-Substituted-ureido-3-carbamoyloxymethyl cephalosporin antibiotics
JPS52125188A (en) * 1976-04-14 1977-10-20 Takeda Chem Ind Ltd Cephalosporin derivatives and their preparation
US4292427A (en) * 1976-11-17 1981-09-29 Merck & Co., Inc. Cephalosporin compounds
US4252974A (en) * 1978-04-07 1981-02-24 Glaxo Group Limited Cephalosporin compounds
US4327093A (en) * 1978-10-24 1982-04-27 Fujisawa Pharmaceutical Co., Ltd. 3,7-Disubstituted-2 or 3-cephem-4-carboxylic acid compounds

Also Published As

Publication number Publication date
EP0010313B1 (de) 1983-01-26
JPS6479188A (en) 1989-03-24
ATE2330T1 (de) 1983-02-15
JPH0369354B2 (de) 1991-10-31
JPS5559195A (en) 1980-05-02
US4327093A (en) 1982-04-27
JPH0144714B2 (de) 1989-09-29
EP0010313A1 (de) 1980-04-30
US4399278A (en) 1983-08-16

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee