ATE232748T1 - Hemmung von gefässverengungen nach eingriffen an den gefässen - Google Patents

Hemmung von gefässverengungen nach eingriffen an den gefässen

Info

Publication number
ATE232748T1
ATE232748T1 AT96915700T AT96915700T ATE232748T1 AT E232748 T1 ATE232748 T1 AT E232748T1 AT 96915700 T AT96915700 T AT 96915700T AT 96915700 T AT96915700 T AT 96915700T AT E232748 T1 ATE232748 T1 AT E232748T1
Authority
AT
Austria
Prior art keywords
matrix
cells
implanted
blood vessel
endothelial cells
Prior art date
Application number
AT96915700T
Other languages
English (en)
Inventor
Elazer Edelman
Aruna Nathan
Matthew A Nugent
Original Assignee
Massachusetts Inst Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Inst Technology filed Critical Massachusetts Inst Technology
Application granted granted Critical
Publication of ATE232748T1 publication Critical patent/ATE232748T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/069—Vascular Endothelial cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/507—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials for artificial blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/005—Ingredients of undetermined constitution or reaction products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/54—Collagen; Gelatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Surgery (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Cell Biology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Compounds Of Unknown Constitution (AREA)
AT96915700T 1995-06-02 1996-05-09 Hemmung von gefässverengungen nach eingriffen an den gefässen ATE232748T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/458,978 US5766584A (en) 1995-06-02 1995-06-02 Inhibition of vascular smooth muscle cell proliferation with implanted matrix containing vascular endothelial cells
PCT/US1996/006707 WO1996038188A1 (en) 1995-06-02 1996-05-09 Inhibition of vascular occlusion following vascular intervention

Publications (1)

Publication Number Publication Date
ATE232748T1 true ATE232748T1 (de) 2003-03-15

Family

ID=23822888

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96915700T ATE232748T1 (de) 1995-06-02 1996-05-09 Hemmung von gefässverengungen nach eingriffen an den gefässen

Country Status (8)

Country Link
US (1) US5766584A (de)
EP (1) EP0850073B1 (de)
JP (2) JP3941881B2 (de)
AT (1) ATE232748T1 (de)
AU (1) AU714559B2 (de)
CA (1) CA2222497C (de)
DE (1) DE69626290T2 (de)
WO (1) WO1996038188A1 (de)

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NZ533467A (en) 1993-07-19 2006-02-24 Angiotech Pharm Inc Anti-angiogenic compositions and methods of use
NZ505584A (en) 1996-05-24 2002-04-26 Univ British Columbia Delivery of a therapeutic agent to the smooth muscle cells of a body passageway via an adventia
US20020077564A1 (en) * 1996-07-29 2002-06-20 Farallon Medsystems, Inc. Thermography catheter
US20080305999A1 (en) * 1996-11-01 2008-12-11 John Francis Martin Therapeutic use of growth factor, and delivery device, especially for the treatment of intimal hyperplasia
US20040015069A1 (en) * 1996-12-27 2004-01-22 Brown David Lloyd System for locating inflamed plaque in a vessel
GB9809082D0 (en) * 1998-04-28 1998-06-24 Eurogene Limited Delivery device
US20030039694A1 (en) * 1998-04-28 2003-02-27 Martin John Francis Periadventitial delivery device
US6375680B1 (en) * 1998-12-01 2002-04-23 St. Jude Medical, Inc. Substrates for forming synthetic tissues
US6824549B1 (en) * 2000-06-07 2004-11-30 Iris Ginron Chao Method & device for making reversed bypass with cultured vessel in situ
US20040097990A1 (en) * 1999-01-27 2004-05-20 Zhao Iris Ginron Graft material, device & method of making
US6333347B1 (en) 1999-01-29 2001-12-25 Angiotech Pharmaceuticals & Advanced Research Tech Intrapericardial delivery of anti-microtubule agents
US6328762B1 (en) 1999-04-27 2001-12-11 Sulzer Biologics, Inc. Prosthetic grafts
US6921412B1 (en) 1999-05-18 2005-07-26 Cryolife, Inc. Self-supporting, shaped, three-dimensional biopolymeric materials and methods
JP3603179B2 (ja) 1999-09-09 2004-12-22 グンゼ株式会社 心血管系組織培養用基材および組織再生法
US6730313B2 (en) * 2000-01-25 2004-05-04 Edwards Lifesciences Corporation Delivery systems for periadventitial delivery for treatment of restenosis and anastomotic intimal hyperplasia
ATE494014T1 (de) * 2000-10-24 2011-01-15 Cryolife Inc Bioprothetischer füller und methoden, insbesondere für die bildung von bandscheibenbioprothesen in situ
US20040241211A9 (en) * 2000-11-06 2004-12-02 Fischell Robert E. Devices and methods for reducing scar tissue formation
EP1416946B1 (de) * 2000-11-07 2017-12-20 CryoLife, Inc. Expandierbare schaumähnliche biomaterialien und verfahren
MXPA03006315A (es) * 2001-01-16 2004-12-03 Vascular Therapies Llc Dispositivo que se puede implantar y que contiene un material matriz que se puede reabsorber y medicamentos antiproliferativos para prevenir o tratar fallas de acceso vascular por hemodialisis y de otros injertos vasculares.
JP3970013B2 (ja) * 2001-12-14 2007-09-05 泰晴 野一色 管腔形成誘導性材料および体内挿入用器具
AU2003228808A1 (en) * 2002-05-02 2003-11-17 Regents Of The University Of Minnesota Fibrin-based biomatrix
JP4265888B2 (ja) * 2002-06-12 2009-05-20 株式会社リコー 画像形成装置
WO2004087214A1 (en) 2003-03-28 2004-10-14 Conor Medsystems, Inc. Implantable medical device with beneficial agent concentration gradient
US8034048B2 (en) * 2003-05-05 2011-10-11 Boston Scientific Scimed, Inc. Tissue patches and related delivery systems and methods
US7416546B2 (en) * 2003-05-05 2008-08-26 Boston Scientific Scimed, Inc. Tissue patches and related delivery systems and methods
WO2005003317A2 (en) * 2003-07-01 2005-01-13 Regents Of The University Of Minnesota Engineered blood vessels
WO2005007034A1 (en) 2003-07-08 2005-01-27 The Children's Hospital Of Philadelphia Steroid lipid-modified polyurethane as an implantable biomaterial, the preparation and uses thereof
US20070092550A1 (en) * 2003-10-10 2007-04-26 Cellular Bioengineering, Inc. Methods and compositions for growing corneal endothelial and related cells on biopolymers and creation of artifical corneal transplants
US20050245905A1 (en) * 2004-04-30 2005-11-03 Schmidt Steven P Local drug-delivery system
JP2008522735A (ja) * 2004-12-08 2008-07-03 パーバシス セラピューティクス， インコーポレイテッド 血管アクセスを強化するための方法および組成物
AU2011211370B2 (en) * 2004-12-08 2013-08-15 Shire Regenerative Medicine, Inc. Methods and compositions for enhancing vascular access
CN101268183B (zh) 2005-04-21 2011-11-30 麻省理工学院 改变对外源和内源免疫原（包括同系和非同系细胞、组织或器官）的免疫应答的材料和方法
JP5632580B2 (ja) * 2005-06-21 2014-11-26 シャイア リジェネラティブ メディシン， インコーポレイテッド 脈管アクセスを改善するための方法および組成物
US20070100323A1 (en) * 2005-10-31 2007-05-03 Ludwig Florian N Facilitation of endothelialization by in situ surface modification
US20100204783A1 (en) * 2005-12-06 2010-08-12 Helen Marie Nugent Methods and compositions for enhancing vascular access
JP5372764B2 (ja) * 2006-11-07 2013-12-18 シャイア リジェネラティブ メディシン， インコーポレイテッド 血管形成関連疾患の治療および管理のための材料および方法
US20080176206A1 (en) 2007-01-18 2008-07-24 Toshiharu Shinoka Cardiovascular tissue culture substrate
WO2008156705A1 (en) * 2007-06-13 2008-12-24 Pervasis Therapeutics, Inc. Methods and devices for minimally-invasive delivery of cell-containing flowable compositions
EP2207558A1 (de) 2007-11-06 2010-07-21 Massachusetts Institute of Technology Durch tissue engineering hergestellte endothel- und epithel-implantate zur differentialen und synergistischen regulierung der gewebereparatur
US20110218606A1 (en) * 2010-03-02 2011-09-08 Medtronic Vascular, Inc. Methods for Stabilizing Femoral Vessels
US9114235B2 (en) 2010-05-03 2015-08-25 Cardiovascular Systems, Inc. Therapeutic agent delivery system and method for localized application of therapeutic substances to a biological lumen
FR2960784B1 (fr) 2010-06-04 2012-07-20 Univ Claude Bernard Lyon Nouveaux substituts vasculaires biodegradables
EP2698635A3 (de) 2010-12-01 2014-05-28 The University Of North Carolina At Chapel Hill Verfahren und Zusammensetzungen zum Targeting auf Stellen neovaskulären Wachstums
CN111454467B (zh) * 2020-02-18 2022-07-12 中国人民大学 一种涂抹式生物可降解血管外支架及其制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4418691A (en) * 1981-10-26 1983-12-06 Massachusetts Institute Of Technology Method of promoting the regeneration of tissue at a wound
US4787900A (en) * 1982-04-19 1988-11-29 Massachusetts Institute Of Technology Process for forming multilayer bioreplaceable blood vessel prosthesis
IL78950A (en) * 1985-06-06 1991-12-15 Univ Jefferson Coating for prosthetic devices
US5567612A (en) * 1986-11-20 1996-10-22 Massachusetts Institute Of Technology Genitourinary cell-matrix structure for implantation into a human and a method of making
US5527532A (en) * 1989-11-13 1996-06-18 President And Fellows Of Harvard College Extraluminal regulation of the growth and repair of tubular structures in vivo
WO1991007154A1 (en) * 1989-11-13 1991-05-30 President And Fellows Of Harvard College EXTRALUMINAL REGULATION OF THE GROWTH AND REPAIR OF TUBULAR STRUCTURES ιIN VIVO
US5540928A (en) * 1991-02-27 1996-07-30 President And Fellows Of Harvard College Extraluminal regulation of the growth and repair of tubular structures in vivo
WO1993002188A1 (en) * 1991-07-15 1993-02-04 Oklahoma Medical Research Foundation Universal donor cells
US5336615A (en) * 1992-01-06 1994-08-09 Yale University Genetically engineered endothelial cells exhibiting enhanced migration and plasminogen activator activity
US5399665A (en) * 1992-11-05 1995-03-21 Massachusetts Institute Of Technology Biodegradable polymers for cell transplantation
CA2186375A1 (en) * 1994-04-29 1995-11-09 William Carl Bruchman Improved blood contact surfaces using endothelium on a subendothelial extracellular matrix

Also Published As

Publication number Publication date
DE69626290T2 (de) 2003-12-04
CA2222497A1 (en) 1996-12-05
EP0850073B1 (de) 2003-02-19
WO1996038188A1 (en) 1996-12-05
JP2005254000A (ja) 2005-09-22
AU714559B2 (en) 2000-01-06
JP3941881B2 (ja) 2007-07-04
AU6292896A (en) 1996-12-18
JPH11506364A (ja) 1999-06-08
DE69626290D1 (de) 2003-03-27
CA2222497C (en) 2008-07-29
US5766584A (en) 1998-06-16
EP0850073A1 (de) 1998-07-01

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