ATE232210T1 - Verfahren zur herstellung von erythromicin a-oxim - Google Patents

Verfahren zur herstellung von erythromicin a-oxim

Info

Publication number
ATE232210T1
ATE232210T1 AT97907949T AT97907949T ATE232210T1 AT E232210 T1 ATE232210 T1 AT E232210T1 AT 97907949 T AT97907949 T AT 97907949T AT 97907949 T AT97907949 T AT 97907949T AT E232210 T1 ATE232210 T1 AT E232210T1
Authority
AT
Austria
Prior art keywords
oxime
erythromicin
producing
erythromycin
isopropanol
Prior art date
Application number
AT97907949T
Other languages
English (en)
Inventor
Sou-Jen Chang
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24526649&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE232210(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of ATE232210T1 publication Critical patent/ATE232210T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT97907949T 1996-04-10 1997-02-27 Verfahren zur herstellung von erythromicin a-oxim ATE232210T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/630,306 US5808017A (en) 1996-04-10 1996-04-10 Process for preparing erythromycin A oxime
PCT/US1997/003177 WO1997038000A1 (en) 1996-04-10 1997-02-27 Process for preparing erythromycin a oxime

Publications (1)

Publication Number Publication Date
ATE232210T1 true ATE232210T1 (de) 2003-02-15

Family

ID=24526649

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97907949T ATE232210T1 (de) 1996-04-10 1997-02-27 Verfahren zur herstellung von erythromicin a-oxim

Country Status (8)

Country Link
US (1) US5808017A (de)
EP (1) EP0970099B1 (de)
JP (1) JP4004068B2 (de)
AT (1) ATE232210T1 (de)
DE (1) DE69718942T2 (de)
DK (1) DK0970099T3 (de)
ES (1) ES2191821T3 (de)
WO (1) WO1997038000A1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9811674A (pt) * 1997-07-08 2000-09-19 Biochemie Sa Solvatos oxima de eritromicina a
CA2245398C (en) * 1998-08-21 2002-01-29 Apotex Inc. Azithromycin monohydrate isopropanol clathrate and methods for the manufacture thereof
IN190782B (de) * 1998-09-30 2003-08-23 Max India Ltd
US6437106B1 (en) 1999-06-24 2002-08-20 Abbott Laboratories Process for preparing 6-o-substituted erythromycin derivatives
IL150227A0 (en) * 1999-12-16 2002-12-01 Teva Pharma Processes for preparing clarithromycin polymorphs and novel polymorph iv
US6590084B2 (en) 1999-12-20 2003-07-08 Merial Process for preparing and isolating 9-deoxo-9 (Z)-hydroxyiminoerythromycin A
FR2802534B1 (fr) * 1999-12-20 2002-02-01 Merial Sas Procede pour preparer et isoler la 9-deoxo-9 (z)- hydroxyiminoerythromycine a
AU2261901A (en) * 2000-01-11 2001-07-24 Teva Pharma Processes for preparing clarithromycin polymorphs
US6544555B2 (en) 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
EP1313486A1 (de) 2000-02-29 2003-05-28 Teva Pharmaceutical Industries Ltd. Verfahren zur herstellung des clarithromycins und eines clarithromycin-zwischenprodukt; clarithromycin wesentlich frei von oxime; und pharmazeutische zusammensetzung die sie enthalten
BR0109544A (pt) * 2000-03-28 2003-06-10 Biochemie Gmbh Partìculas granuladas com sabor ocultado
ATE306491T1 (de) 2000-08-23 2005-10-15 Wockhardt Ltd Verfahren zur herstellung von wasserfreiem azithromycin
US20020068078A1 (en) 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
ES2243798T3 (es) * 2001-11-07 2005-12-01 Aventis Pharma Deutschland Gmbh Procedimiento para la produccion de desclaritromicina, asi como prodcutos intermedios.
JP2006528190A (ja) 2003-07-21 2006-12-14 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
US8313776B2 (en) 2003-07-21 2012-11-20 Shionogi Inc. Antibiotic product, use and formulation thereof
JP2006528185A (ja) 2003-07-21 2006-12-14 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
CA2535177A1 (en) 2003-08-11 2005-02-24 Advancis Pharmaceutical Corporation Robust pellet
CA2535398C (en) 2003-08-12 2013-11-12 Advancis Pharmaceuticals Corporation Antibiotic product, use and formulation thereof
AU2004270170B2 (en) * 2003-08-29 2011-01-27 Shionogi, Inc. Antibiotic product, use and formulation thereof
WO2005027877A1 (en) 2003-09-15 2005-03-31 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
JP2008505124A (ja) 2004-07-02 2008-02-21 アドバンシス ファーマスーティカル コーポレイション パルス送達用錠剤
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
US8778924B2 (en) 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
US7595300B2 (en) 2005-12-13 2009-09-29 Kosan Biosciences Incorporated 7-quinolyl ketolide antibacterial agents
US8299052B2 (en) 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication
WO2009023191A2 (en) * 2007-08-09 2009-02-19 Teva Pharmaceutical Industries Ltd. An improved process for the preparation of clarithromycin
CN101362783B (zh) * 2008-10-06 2011-12-07 浙江国邦药业有限公司 一种红霉素a(e)肟的制备方法
CN102911225A (zh) * 2011-08-04 2013-02-06 山东方明药业集团股份有限公司 红霉素a肟的清洁化合成方法及其特别组合的反应设备
CN103897002A (zh) * 2012-12-31 2014-07-02 菏泽市方明制药有限公司 一种粗品硫氰酸红霉素制备红霉素a9-肟的方法
CN103923142B (zh) * 2014-04-30 2017-01-11 浙江震元制药有限公司 一种罗红霉素中间体的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1100504A (en) * 1967-08-16 1968-01-24 Pliva Pharm & Chem Works Erythromycin oxime and 9-amino-3-o-cladinosyl-5-o-desosaminyl-6,11,12-trihydroxy-2,4,6,8,10,12-hexamethylpentadecane-13-olide
US4150220A (en) * 1977-02-04 1979-04-17 Pfizer Inc. Semi-synthetic 4"-erythromycin A derivatives
US4526889A (en) * 1982-11-15 1985-07-02 Pfizer Inc. Epimeric azahomoerythromycin A derivative, intermediates and method of use
JPS60214796A (ja) * 1984-04-06 1985-10-28 Taisho Pharmaceut Co Ltd ６−０−メチルエリスロマイシン類の製法
JP2751385B2 (ja) * 1988-05-19 1998-05-18 大正製薬株式会社 エリスロマイシンａオキシム及びその塩の製造方法

Also Published As

Publication number Publication date
EP0970099B1 (de) 2003-02-05
DE69718942T2 (de) 2003-12-11
WO1997038000A1 (en) 1997-10-16
JP2000508311A (ja) 2000-07-04
DE69718942D1 (de) 2003-03-13
EP0970099A1 (de) 2000-01-12
US5808017A (en) 1998-09-15
JP4004068B2 (ja) 2007-11-07
ES2191821T3 (es) 2003-09-16
DK0970099T3 (da) 2003-05-26

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