ATE228165T1 - Herstellung von d-alpha-aminosäuren, unter verwendung von mit dem carbamoylase-hydantoinase- operon-transformierten bakterien - Google Patents

Herstellung von d-alpha-aminosäuren, unter verwendung von mit dem carbamoylase-hydantoinase- operon-transformierten bakterien

Info

Publication number
ATE228165T1
ATE228165T1 AT96117455T AT96117455T ATE228165T1 AT E228165 T1 ATE228165 T1 AT E228165T1 AT 96117455 T AT96117455 T AT 96117455T AT 96117455 T AT96117455 T AT 96117455T AT E228165 T1 ATE228165 T1 AT E228165T1
Authority
AT
Austria
Prior art keywords
amino acids
carbamoylase
hydantoinase
operon
production
Prior art date
Application number
AT96117455T
Other languages
English (en)
Inventor
Renata Grifantini
Giuliano Galli
Guido Grandi
Giovanna Carpani
Original Assignee
Enitecnologie Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Enitecnologie Spa filed Critical Enitecnologie Spa
Application granted granted Critical
Publication of ATE228165T1 publication Critical patent/ATE228165T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C12P41/009—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving hydantoins or carbamoylamino compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
AT96117455T 1995-11-23 1996-10-31 Herstellung von d-alpha-aminosäuren, unter verwendung von mit dem carbamoylase-hydantoinase- operon-transformierten bakterien ATE228165T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT95MI002432A IT1276163B1 (it) 1995-11-23 1995-11-23 Procedimento migliorato per la preparazione di d-alfa-amminoacidi

Publications (1)

Publication Number Publication Date
ATE228165T1 true ATE228165T1 (de) 2002-12-15

Family

ID=11372580

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96117455T ATE228165T1 (de) 1995-11-23 1996-10-31 Herstellung von d-alpha-aminosäuren, unter verwendung von mit dem carbamoylase-hydantoinase- operon-transformierten bakterien

Country Status (6)

Country Link
US (1) US5834258A (de)
EP (1) EP0775748B1 (de)
JP (1) JP3768309B2 (de)
AT (1) ATE228165T1 (de)
DE (1) DE69624898D1 (de)
IT (1) IT1276163B1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6524837B1 (en) 1999-03-29 2003-02-25 California Institute Of Technology Hydantoinase variants with improved properties and their use for the production of amino acids
NL1019416C2 (nl) * 2001-11-23 2003-06-02 Dsm Nv Werkwijze voor het bereiden van een enantiomeer verrijkt a-aminozuur.
JPWO2003085108A1 (ja) * 2002-04-10 2005-08-11 味の素株式会社 ヒダントイナーゼ遺伝子及びカルバミラーゼ遺伝子を有する組換えｄｎａ、並びにアミノ酸製造方法
JP6363326B2 (ja) * 2013-03-11 2018-07-25 株式会社コーセー 酵母・細菌共通培養方法およびこれに用いる酵母・細菌共通培養培地
CN111621452A (zh) * 2019-02-28 2020-09-04 中国科学院微生物研究所 一株生产d-对羟基苯甘氨酸的枯草芽孢杆菌
CN112080532A (zh) * 2020-09-27 2020-12-15 铜陵利夫生物科技有限公司 一种双酶法生产d-对羟基苯甘氨酸的方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1046399B (it) 1975-05-12 1980-06-30 Snam Progetti Procedimento per la preparazione di d carbamil amminoacidi e dei corrispondenti d amminoacidi
IT1039757B (it) 1975-07-10 1979-12-10 Snam Progetti Complessi enzimatici atti a trasformare idantoine raceme in am minoacidi otticamente attivi e loro applicazione
IT1109506B (it) 1978-05-23 1985-12-16 Snam Progetti Processo enzimatico-microbiologico per la produzione di amminoacidi otticamente attivi a partire da idantoine e/o carbamil-derivati racemi
FR2456728A1 (fr) 1979-05-15 1980-12-12 Aec Chim Organ Biolog Procede de preparation de d-a-aminoacides
JPS61212292A (ja) 1985-03-19 1986-09-20 Mitsui Toatsu Chem Inc Ｄ−α−アミノ酸の製造方法
DE3535987A1 (de) 1985-10-09 1987-04-23 Basf Ag Verfahren zur herstellung von meophilen mikroorganismen, die eine bei hoeherer temperatur aktive d-hydantoinase enthalten
FR2620731B1 (fr) 1987-09-21 1990-03-23 Hoechst France Nouveau systeme enzymatique, son procede de preparation et son application notamment dans la preparation de la d-parahydroxyphenylglycine
US5565344A (en) 1990-12-07 1996-10-15 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Process for production of D-α-amino acids
EP1568778A1 (de) * 1992-06-30 2005-08-31 Smithkline Beecham Plc Hydantoinase aus Agrobacterium
WO1994005477A1 (en) * 1992-09-07 1994-03-17 Friends Of Freesia Co., Ltd. Hopper disposing method and hopper for hopper-carrying machines
IT1274167B (it) * 1994-04-15 1997-07-15 Eniricerche Spa Procedimento per la produzione di d- -amminoacidi
WO1996000296A1 (fr) * 1994-06-24 1996-01-04 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Procede de production de d-amino acide au moyen d'une preparation a base d'une enzyme composite immobilisee

Also Published As

Publication number Publication date
EP0775748A3 (de) 1999-04-07
IT1276163B1 (it) 1997-10-27
EP0775748B1 (de) 2002-11-20
ITMI952432A1 (it) 1997-05-23
JPH09187286A (ja) 1997-07-22
ITMI952432A0 (de) 1995-11-23
JP3768309B2 (ja) 2006-04-19
EP0775748A2 (de) 1997-05-28
DE69624898D1 (de) 2003-01-02
US5834258A (en) 1998-11-10

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