ATE225345T1 - Auf serotonin-verwandte systeme wirkende piperidin-derivate - Google Patents

Auf serotonin-verwandte systeme wirkende piperidin-derivate

Info

Publication number
ATE225345T1
ATE225345T1 AT99305095T AT99305095T ATE225345T1 AT E225345 T1 ATE225345 T1 AT E225345T1 AT 99305095 T AT99305095 T AT 99305095T AT 99305095 T AT99305095 T AT 99305095T AT E225345 T1 ATE225345 T1 AT E225345T1
Authority
AT
Austria
Prior art keywords
serotonin
related systems
piperidine derivatives
derivatives acting
acting
Prior art date
Application number
AT99305095T
Other languages
English (en)
Inventor
Daniel Timothy Kohlman
Sidney Xi Liang
Yao-Chang Xu
Larry Wayne Hertel
David Taiwai Wong
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE225345T1 publication Critical patent/ATE225345T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
AT99305095T 1998-06-30 1999-06-29 Auf serotonin-verwandte systeme wirkende piperidin-derivate ATE225345T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9124198P 1998-06-30 1998-06-30

Publications (1)

Publication Number Publication Date
ATE225345T1 true ATE225345T1 (de) 2002-10-15

Family

ID=22226762

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99305095T ATE225345T1 (de) 1998-06-30 1999-06-29 Auf serotonin-verwandte systeme wirkende piperidin-derivate

Country Status (12)

Country Link
US (1) US6436964B1 (de)
EP (1) EP0982304B1 (de)
JP (1) JP2002519323A (de)
AR (1) AR019178A1 (de)
AT (1) ATE225345T1 (de)
AU (1) AU4726699A (de)
CA (1) CA2336117A1 (de)
CO (1) CO5080791A1 (de)
DE (1) DE69903239T2 (de)
ES (1) ES2181366T3 (de)
PE (1) PE20000763A1 (de)
WO (1) WO2000000198A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1091741A4 (de) 1998-06-30 2002-12-18 Lilly Co Eli Azepine derivaten, welche über serotoninverwandtes system wirkung haben
EP1196413A2 (de) * 1999-06-29 2002-04-17 Eli Lilly And Company Herstellung von 7-substituierten benzothiophenen
JP2003522122A (ja) * 1999-06-29 2003-07-22 イーライ・リリー・アンド・カンパニー 置換ピペリジン−4−オンの製造
AU768339B2 (en) * 1999-07-29 2003-12-11 Eli Lilly And Company Serotonergic benzofurans
WO2001009126A1 (en) * 1999-07-29 2001-02-08 Eli Lilly And Company Serotonergic benzothiophenes
US6881733B1 (en) 1999-07-29 2005-04-19 Eli Lilly And Company Serotonergic benzofurans
MXPA02001994A (es) * 1999-09-29 2002-09-18 Lilly Co Eli Derivados de piperidina como inhibidores de la reabsorcion.
BR0014668A (pt) * 1999-09-29 2002-06-18 Lilly Co Eli Derivados de piperidina como inibidores de reabsorção de serotonina
US20040058962A1 (en) * 2002-06-14 2004-03-25 Amedeo Leonardi Phenylalkylamines and pyridylalkylamines
ITMI20021329A1 (it) * 2002-06-14 2003-12-15 Recordati Chem Pharm Nuove ossialchilammine sostituite
AU2003268361A1 (en) * 2002-08-30 2004-03-19 Watson Pharmaceuticals, Inc. Drug delivery system for treating urinary incontinence
EP1587788B9 (de) 2002-09-17 2007-10-24 F. Hoffmann-La Roche Ag 2,7-disubstituierteindole und ihre verwendung als 5-ht6 modulatoren
ATE402923T1 (de) 2002-09-17 2008-08-15 Hoffmann La Roche 2,4-substituierte indole und deren verwendung als 5-ht6 modulatoren
TWI320783B (en) 2005-04-14 2010-02-21 Otsuka Pharma Co Ltd Heterocyclic compound
US7893085B2 (en) 2006-08-21 2011-02-22 Genentech, Inc Aza-benzothiophenyl compounds and methods of use
WO2016134684A1 (de) 2015-02-24 2016-09-01 Mso Messtechnik Und Ortung Gmbh Verfahren zur messung des erntegutmassestroms am feldhäcksler
NL1041393B1 (en) 2015-07-07 2017-01-30 Kessener B V Method and device providing a liquid display.
DE102016002899B4 (de) 2016-03-09 2020-03-12 Johannes Kraus Feuerraum mit verbessertem Ausbrand
DE202016005695U1 (de) 2016-09-12 2016-10-04 Jürgen Raudis Seifenabstandhalter zum Trocknen fester Seifen mit Seifenabtropfbehälter

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0006524A1 (de) 1978-06-22 1980-01-09 Ciba-Geigy Ag Neue Tetrahydropyridin- und Piperidinderivate und deren Säureadditionssalze, Verfahren zu deren Herstellung und solche enthaltende pharmazeutische Zusammensetzungen
GB2056435A (en) * 1979-06-26 1981-03-18 Ciba Geigy Ag Novel Tetrahydropyridine and Piperidine Substituted Benzofuranes and Related Compounds
FR2670491B1 (fr) * 1990-12-14 1993-02-05 Adir Nouvelles piperazines 1,4-disubstituees, leur procede de preparation et les compositions pharmaceutiques les renfermant.
NZ240863A (en) * 1991-09-11 1995-04-27 Mcneilab Inc Substituted 4-aryl piperidine and 4-aryl piperazine derivatives, preparation and pharmaceutical compositions thereof
AU675964B2 (en) * 1992-08-05 1997-02-27 John Wyeth & Brother Limited Amide derivatives
DK148392D0 (da) * 1992-12-09 1992-12-09 Lundbeck & Co As H Heterocykliske forbindelser
GB9300195D0 (en) 1993-01-06 1993-03-03 Wyeth John & Brother Ltd Piperazine derivatives
US5576321A (en) * 1995-01-17 1996-11-19 Eli Lilly And Company Compounds having effects on serotonin-related systems
ATE340173T1 (de) * 1996-03-29 2006-10-15 Duphar Int Res Piperazin- und piperidin- derivate
DE69819173T2 (de) * 1997-07-25 2004-04-15 H. Lundbeck A/S Indole und 2,3-dihydroindolderivate, ihre herstellung und verwendung
FR2769312B1 (fr) * 1997-10-03 1999-12-03 Adir Nouveaux composes de l'indanol, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
CA2336117A1 (en) 2000-01-06
US6436964B1 (en) 2002-08-20
JP2002519323A (ja) 2002-07-02
ES2181366T3 (es) 2003-02-16
AU4726699A (en) 2000-01-17
DE69903239D1 (de) 2002-11-07
AR019178A1 (es) 2001-12-26
EP0982304B1 (de) 2002-10-02
DE69903239T2 (de) 2003-09-11
PE20000763A1 (es) 2000-08-30
CO5080791A1 (es) 2001-09-25
EP0982304A1 (de) 2000-03-01
WO2000000198A1 (en) 2000-01-06
WO2000000198A8 (en) 2000-03-23

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Legal Events

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