ATE222914T1 - Diester-derivate von acyclovir - Google Patents
Diester-derivate von acyclovirInfo
- Publication number
- ATE222914T1 ATE222914T1 AT98921224T AT98921224T ATE222914T1 AT E222914 T1 ATE222914 T1 AT E222914T1 AT 98921224 T AT98921224 T AT 98921224T AT 98921224 T AT98921224 T AT 98921224T AT E222914 T1 ATE222914 T1 AT E222914T1
- Authority
- AT
- Austria
- Prior art keywords
- acyclovir
- hydroxy
- animal
- individual
- disclosed
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
- C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US85715097A | 1997-05-15 | 1997-05-15 | |
US5022098A | 1998-03-27 | 1998-03-27 | |
PCT/US1998/009944 WO1998051692A1 (en) | 1997-05-15 | 1998-05-15 | Acyclovir diester derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE222914T1 true ATE222914T1 (de) | 2002-09-15 |
Family
ID=26728027
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT98921224T ATE222914T1 (de) | 1997-05-15 | 1998-05-15 | Diester-derivate von acyclovir |
Country Status (8)
Country | Link |
---|---|
US (2) | US6031096A (de) |
EP (1) | EP0981532B1 (de) |
JP (1) | JP2001527561A (de) |
AT (1) | ATE222914T1 (de) |
AU (1) | AU731225C (de) |
CA (1) | CA2289969A1 (de) |
DE (1) | DE69807464T2 (de) |
WO (1) | WO1998051692A1 (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6458772B1 (en) | 1909-10-07 | 2002-10-01 | Medivir Ab | Prodrugs |
EP0981532B1 (de) * | 1997-05-15 | 2002-08-28 | Drug Innovation & Design, Inc. | Diester-derivate von acyclovir |
BRPI0003386B8 (pt) * | 2000-08-08 | 2021-05-25 | Cristalia Produtos Quim Farmaceuticos Ltda | pró-droga homo ou heterodiméricas úteis no tratamento de doenças ou disfunções mediadas por fosfodiesterases; composições farmacêuticas contendo a pró-droga ou seus sais farmacêuticos aceitáveis; processo de obtenção destas pró-drogas |
US8010843B2 (en) * | 2005-12-14 | 2011-08-30 | American Megatrends, Inc. | System and method for debugging a target computer using SMBus |
EP2291348A4 (de) | 2008-05-20 | 2013-05-15 | Neurogesx Inc | Wasserlösliche acetaminophenanaloga |
KR101677126B1 (ko) | 2008-05-20 | 2016-11-22 | 노이로제스엑스, 인코포레이티드 | 탄산염 프로드러그 및 그것의 사용 방법 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4199574A (en) * | 1974-09-02 | 1980-04-22 | Burroughs Wellcome Co. | Methods and compositions for treating viral infections and guanine acyclic nucleosides |
GB1523865A (en) * | 1974-09-02 | 1978-09-06 | Wellcome Found | Purine compunds and salts thereof |
US4146715A (en) * | 1975-08-27 | 1979-03-27 | Burroughs Wellcome Co. | 2-amido-9-(2-acyloxyethoxymethyl)hypoxanthines |
US4816447A (en) * | 1981-08-26 | 1989-03-28 | Merck & Co., Inc. | Anti-viral guanine compounds |
IT1170232B (it) * | 1983-10-31 | 1987-06-03 | Anna Gioia Stendardi | Composizioni terapeutiche ad attivita' antivirale |
US4806642A (en) * | 1984-10-05 | 1989-02-21 | Warner-Lambert Company | Purine derivatives |
US4845084A (en) * | 1984-01-26 | 1989-07-04 | Merck & Co., Inc. | Phosphate derivatives of substituted butyl guanines, antiviral compositions containing them, and methods of treating viral infections with them |
EP0353955A3 (de) * | 1988-08-02 | 1991-08-14 | Beecham Group Plc | Chemische Verbindungen |
DK24089D0 (da) * | 1989-01-20 | 1989-01-20 | Hans Bundgaard | Novel prodrug derivatives of biologically active agents containing hydroxyl groups or nh-acidic groups |
CA2083386C (en) * | 1990-06-13 | 1999-02-16 | Arnold Glazier | Phosphorous prodrugs |
US5627165A (en) * | 1990-06-13 | 1997-05-06 | Drug Innovation & Design, Inc. | Phosphorous prodrugs and therapeutic delivery systems using same |
US5879700A (en) * | 1991-10-15 | 1999-03-09 | Hostetler; Karl Y. | Nucleoside analogue phosphates for topical use |
US5580571A (en) * | 1991-10-15 | 1996-12-03 | Hostetler; Karl Y. | Nucleoside analogues |
US5627185A (en) * | 1994-11-23 | 1997-05-06 | Gosselin; Gilles | Acyclovir derivatives as antiviral agents |
US5789589A (en) | 1996-04-22 | 1998-08-04 | Drug Innovation & Design, Inc. | Guanine analog phosphates |
EP0981532B1 (de) * | 1997-05-15 | 2002-08-28 | Drug Innovation & Design, Inc. | Diester-derivate von acyclovir |
-
1998
- 1998-05-15 EP EP98921224A patent/EP0981532B1/de not_active Expired - Lifetime
- 1998-05-15 AU AU73885/98A patent/AU731225C/en not_active Ceased
- 1998-05-15 JP JP54956898A patent/JP2001527561A/ja active Pending
- 1998-05-15 US US09/080,064 patent/US6031096A/en not_active Expired - Fee Related
- 1998-05-15 WO PCT/US1998/009944 patent/WO1998051692A1/en active IP Right Grant
- 1998-05-15 CA CA002289969A patent/CA2289969A1/en not_active Abandoned
- 1998-05-15 AT AT98921224T patent/ATE222914T1/de not_active IP Right Cessation
- 1998-05-15 DE DE69807464T patent/DE69807464T2/de not_active Expired - Fee Related
-
2000
- 2000-02-28 US US09/514,552 patent/US6214811B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO1998051692A1 (en) | 1998-11-19 |
CA2289969A1 (en) | 1998-11-19 |
US6214811B1 (en) | 2001-04-10 |
DE69807464T2 (de) | 2003-05-15 |
AU731225B2 (en) | 2001-03-29 |
EP0981532B1 (de) | 2002-08-28 |
AU7388598A (en) | 1998-12-08 |
DE69807464D1 (de) | 2002-10-02 |
AU731225C (en) | 2001-10-18 |
US6031096A (en) | 2000-02-29 |
EP0981532A1 (de) | 2000-03-01 |
JP2001527561A (ja) | 2001-12-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |